/manager/Index ${session.getAttribute("locale")} 5 Neuroimmune regulation of female reproduction in health and disease /manager/Repository/uon:47704 Wed 25 Jan 2023 10:34:30 AEDT ]]> Functional programming of the autonomic nervous system by early life immune exposure: implications for anxiety /manager/Repository/uon:15023 Wed 11 Apr 2018 16:31:59 AEST ]]> Neonatal immune activation depletes the ovarian follicle reserve and alters ovarian acute inflammatory mediators in neonatal rats /manager/Repository/uon:33905 Tnfa, mitogen-activated protein kinase 8 (Mapk8/Jnk1), and growth differentiation factor 9 (Gdf9) (P < 0.05). Mass spectrometry and cell signaling pathway analysis indicated upregulation of cellular pathways associated with acute phase signaling, and cellular survival and assembly. Apoptosis assessed by terminal deoxynucleotidyl transferase dUTP nick end labeling indicated significantly increased positive staining in the ovaries of LPS-treated neonates. These findings suggest that increased proinflammatory signaling within the neonatal ovary may be responsible for the LPS-induced depletion of the primordial follicle pool. These findings also have implications for female reproductive health, as the ovarian reserve is a major determinate of female reproductive longevity.]]> Wed 09 Feb 2022 15:58:52 AEDT ]]> Early life peripheral lipopolysaccharide challenge reprograms catecholaminergic neurons /manager/Repository/uon:30987 Mon 20 Nov 2023 14:18:12 AEDT ]]>