https://nova.newcastle.edu.au/vital/access/ /manager/Index ${session.getAttribute("locale")} 5 Absence of airway inflammation in a large proportion of adolescents with asthma https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:26123 Thu 28 Oct 2021 13:04:19 AEDT ]]> Relationship between airway neutrophilia and ageing in asthmatics and non-asthmatics https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:18993 95th percentile of non-asthmatic counts for any given age group) were significantly more likely to be asthmatic (odds ratio = 2.5; 95% CI: 1.3, 5.0), with the greatest effect observed in the older age group. Other factors that independently associated with increased sputum neutrophil levels included atopy in non-asthmatic adults, male gender and current use of ICS in asthmatic adults. Age-specific reference values for neutrophil percentage were under 20 years-76%, 20–40 years-62%, 40–60 years-63% and over 60 years-67%. Conclusions: Airway neutrophilia is related to age in adults, with a neutrophilic asthma phenotype present in older adults. The use of appropriate age-specific reference values is recommended for future studies aimed at elucidating the role of neutrophils in asthma.]]> Sat 24 Mar 2018 08:05:37 AEDT ]]> Innate immunity in asthma https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:5103 Sat 24 Mar 2018 07:48:49 AEDT ]]>