https://nova.newcastle.edu.au/vital/access/ /manager/Index ${session.getAttribute("locale")} 5 Norcantharidin analogues with nematocidal activity in Haemonchus contortus https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:12397 50s of 25–40 μM. The high ‘hit rate’ (5.6%) indicates that the approach taken here has advantages over conventional drug screening methods. A major advantage of norcantharidin analogues over some other currently available anthelmintics is that they can be produced in one to two steps in large amounts at low cost and high purity, and do not require any additional steps for the isolation of the active isomer. This positions them well for commercial development.]]> Sat 24 Mar 2018 08:15:45 AEDT ]]> Discovery of acrylonitrile-based small molecules active against Haemonchus contortus https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:20974 Sat 24 Mar 2018 07:54:19 AEDT ]]>