Juxtamembrane mutant V560GKit is more sensitive to Imatinib (ST1571) compared with wild-type c-Kit whereas the kinase domain mutant D816VKit is resistant

- Frost, Michelle J., Ferrao, Petranel T., Hughes, Timothy P., Ashman, Leonie K.

Src family kinases are involved in the differential signaling from two splice forms of c-Kit

- Voytyuk, Olexandra, Lennartsson, Johan, Mogi, Akira, Caruana, Georgina, Courtneidge, Sara, Ashman, Leonie K., Ronnstrand, Lars

Characterization of mice lacking the tetraspanin superfamily member CD151

- Wright, Mark D., Geary, Sean M., Fitter, Stephen, Moseley, Gregory W., Lau, Lai-Man, Sheng, Kuo-Ching, Apostolopoulos, Vasso, Stanley, Edouard G., Jackson, Denise E., Ashman, Leonie K.

An in vivo tumor model exploiting metabolic response as a biomarker for targeted drug development

- Cullinane, C., Dorow, D. S., Kansara, M., Conus, N., Binns, D., Hicks, R. J., Ashman, Leonie K., McArthur, G. A., Thomas, D. M.

Colocalization of the tetraspanins, CO-029 and CD151, with integrins in human pancreatic adenocarcinoma: Impact on cell motility

- Gesierich, S., Paret, C., Hildebrand, D., Weitz, J., Zgraggen, K., Schmitz-Winnenthal, F. H., Horejsi, V., Yoshie, O., Herlyn, D., Ashman, Leonie K., Zoller, M.

Evidence for the involvement of PECAM-1 in a receptor mediated signal-transduction pathway regulating capacitation-associated tyrosine phosphorylation in human spermatozoa

- Nixon, Brett, Paul, Jonathan W., Spiller, Cassy M., Attwell-Heap, Abigail G., Ashman, Leonie K., Aitken, R. John

Wound healing is defective in mice lacking tetraspanin CD151

- Cowin, Allison J., Adams, Damian, Geary, Sean M., Wright, Mark D., Jones, Jonathan C. R., Ashman, Leonie K.

Deletion of Cd151 results in a strain-dependent glomerular disease due to severe alterations of the glomerular basement membrane

- Baleato, Rosa, Guthrie, Petrina L., Gubler, Marie-Claire, Ashman, Leonie K., Roselli, Severine

Probing the interaction of tetraspanin CD151 with integrin α3β1 using a panel of monoclonal antibodies with distinct reactivities toward the CD151-integrin α3β1 complex

- Yamada, Masashi, Tamura, Yumiko, Sanzen, Noriko, Sato-Nishiuchi, Ryoko, Hasegawa, Hitoshi, Ashman, Leonie K., Rubinstein, Eric, Yanez-Mo, Maria, Sanchez-Madrid, Francisco, Sekiguchi, Kiyotoshi

The role of the tetraspanin CD151 in primary keratinocyte and fibroblast functions: implications for wound healing

- Geary, Sean M., Cowin, Allison J., Copeland, Ben, Baleato, Rosa M., Miyazaki, Kaoru, Ashman, Leonie K.

CD151 (CD151 molecule (Raph blood group))

- Weidenhofer, Judith, Ashman, Leonie K.

Identification of Tspan9 as a novel platelet tetraspanin and the collagen receptor GPVI as a component of tetraspanin microdomains

- Protty, Majd B., Watkins, Nicholas A., Ouwehand, Willem H., Watson, Steve P., Tomlinson, Michael G., Colombo, Dario, Thomas, Steven G., Heath, Victoria L., Herbert, John M. J., Bicknell, Roy, Senis, Yotis A., Ashman, Leonie K., Berditchevski, Fedor

Colony stimulating factor-1 receptor as a target for small molecule inhibitors

- Mashkani, Baratali, Griffith, Renate, Ashman, Leonie K.

Essential requirement for PP2A inhibition by the oncogenic receptor c-KIT suggests PP2A reactivation as a strategy to treat c-KIT⁺ cancers

- Roberts, Kathryn G., Smith, Amanda M., Sim, Alistair T. R., Ashman, Leonie K., Verrills, Nicole M., McDougall, Fiona, Carpenter, Helen, Horan, Martin, Neviani, Paolo, Powell, Jason A., Thomas, Daniel, Guthridge, Mark A., Perrotti, Danilo

The migration and invasion of human prostate cancer cell lines involves CD151 expression

- Ang, Jian, Fang, Bing-Liang, Ashman, Leonie K., Frauman, Albert G.

Expression of biologically active human colony stimulating factor-1 in Pichia pastoris

- Mashkani, Baratali, Odell, Adam F., Byrnes, Ellen M., Griffith, Renate, Ashman, Leonie K.

Genetic ablation of the tetraspanin CD151 reduces spontaneous metastatic spread of prostate cancer in the TRAMP model

- Copeland, Ben T., Bowman, Matthew J., Ashman, Leonie K.

Knockout of the tetraspanin Cd9 in the TRAMP model of de novo prostate cancer increases spontaneous metastases in an organ-specific manner

- Copeland, Ben T., Bowman, Matthew J., Boucheix, Claude, Ashman, Leonie K.

Tetraspanins in cancer

- Ashman, Leonie K., Zöller, Margot

Therapeutic targeting of c-KIT in cancer

- Ashman, Leonie K., Griffith, Renate