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Young, Kelly A.

Robenidine analogues as gram-positive antibacterial agents

Creator: Abraham, Rebecca J. , Stevens, Andrew J. , O'Handley, Ryan , McCluskey, Adam , Trott, Darren J. , Young, Kelly A. , Russell, Cecilia , Qvist, Anastasia , Khazandi, Manouchehr , Wong, Hui San , Abraham, Sam , Ogunniyi, Abiodun D. , Page, Stephen W.
Resource Type: journal article
Date: 2016

Inhibition of dynamin by dynole 34-2 induces cell death following cytokinesis failure in cancer cells

Creator: Chircop, Megan , Perera, Swetha , Sakoff, Jennette , O'Brien, Terence J. , McCluskey, Adam , Robinson, Phillip J. , Mariana, Anna , Lau, Hui , Ma, Maggie P. C. , Gilbert, Jayne , Jones, Nigel C. , Gordon, Christopher P. , Young, Kelly A. , Morokoff, Andrew
Resource Type: journal article
Date: 2011

Wiskostatin and other carbazole scaffolds as off target inhibitors of dynamin I GTPase activity and endocytosis

Creator: Cossar, Peter J. , Cardoso, David , McCluskey, Adam , Mathwin, Daniel , Russell, Cecilia C. , Chiew, Beatrice , Hamilton, Michael P. , Baker, Jennifer R. , Young, Kelly A. , Chau, Ngoc , Robinson, Phillip J.
Resource Type: journal article
Date: 2023

Synthesis and anticancer activity of focused compound libraries from the natural product lead, oroidin

Creator: Dyson, Lauren , Wright, Anthony D. , Young, Kelly A. , Sakoff, Jennette A. , McCluskey, Adam
Resource Type: journal article
Date: 2014

An Ugi-intramolecular Diels-Alder route to highly substituted tetrahydroepoxyisoindole carboxamides

Creator: Gordon, Christopher P. , Young, Kelly A. , Robertson, Mark J. , Hill, Timothy A. , McCluskey, Adam
Resource Type: journal article
Date: 2011

Development of second-generation indole-based dynamin GTPase inhibitors

Creator: Gordon, Christopher P. , Venn-Brown, Barbara , Robertson, Mark J. , Young, Kelly A. , Chau, Ngoc , Mariana, Anna , Whiting, Ainslie , Chircop, Megan , Robinson, Phillip J. , McCluskey, Adam
Resource Type: journal article
Date: 2013

Expanding the utility of flow hydrogenation - a robust protocol restricting hydrodehalogenation

Creator: Hizartzidis, Lacey , Cossar, Peter J. , Robertson, Mark J. , Simone, Michela I. , Young, Kelly A. , McCluskey, Adam , Gordon, Christopher P.
Resource Type: journal article
Date: 2014

Targeting Glioma stem cells by functional inhibition of dynamin 2: a novel treatment strategy for Glioblastoma

Creator: Luwor, Rodney , Morokoff, Andrew P. , Robinson, Phillip J. , Chircop, Megan , McCluskey, Adam , Jones, Nigel C. , Amiridis, Stephanie , D'Abaco, Giovanna , Paradiso, Lucia , Stylli, Stanley S. , Nguyen, Hong P. T. , Tarleton, Mark , Young, Kelly A. , O'Brien, Terence J.
Resource Type: journal article
Date: 2019

Development of 1,8-naphthalimides as clathrin inhibitors

Creator: MacGregor, Kylie A. , Robertson, Mark J. , Young, Kelly A. , von Kleist, Lisa , Stahlschmidt, Wiebke , Whiting, Ainslie , Chau, Ngoc , Robinson, Phillip J. , Haucke, Volker , McCluskey, Adam
Resource Type: journal article
Date: 2014

Pyrimidyn compounds: dual-action small molecule pyrimidine-based dynamin inhibitors

Creator: McGeachie, Andrew B. , Odell, Luke R. , Mariana, Anna , Whiting, Ainslie , Perera, Swetha , Novelle, Aimee , Young, Kelly A. , Deane, Fiona M. , Gilbert, Jayne , Sakoff, Jennette A. , Chircop, Megan , McCluskey, Adam , Quan, Annie , Robinson, Phillip J. , Daniel, James A. , Chau, Ngoc , Hill, Timothy A. , Gorgani, Nick N. , Keating, Damien J. , Cousin, Michael A. , van Dam, Ellen M.
Resource Type: journal article
Date: 2013

Oral administration of a 2-aminopyrimidine robenidine analogue (NCL195) significantly reduces Staphylococcus aureus infection and reduces Escherichia coli infection in combination with sub-inhibitory colistin concentrations in a bioluminescent mouse model

Creator: Nguyen, Hang Thi , Venter, Henrietta , Woolford, Lucy , Young, Kelly A. , Mccluskey, Adam , Garg, Sanjay , Sapula, Sylvia S. , Page, Stephen W. , Ogunniyi, Abiodun David , Trott, Darren J.
Resource Type: journal article
Date: 2023

Pyrimidyn-Based Dynamin Inhibitors as Novel Cytotoxic Agents

Creator: Odell, Luke R. , Chau, Ngoc , Russell, Cecilia C. , Young, Kelly A. , Gilbert, Jayne , Robinson, Phillip J. , Sakoff, Jennette A. , McCluskey, Adam
Resource Type: journal article
Date: 2022

Pyrimidine-based inhibitors of dynamin I GTPase activity: competitive inhibition at the pleckstrin homology domain

Creator: Odell, Luke R. , Abdel-Hamid, Mohammed K. , McCluskey, Adam , Hill, Timothy A. , Chau, Ngoc , Young, Kelly A. , Deane, Fiona M. , Sakoff, Jennette A. , Andersson, Sofia , Daniel, James A. , Robinson, Phillip J.
Resource Type: journal article
Date: 2017

Prodrugs of the Archetypal Dynamin Inhibitor Bis-T-22

Creator: Odell, Luke R. , Robertson, Mark J. , Young, Kelly A. , McGeachie, Andrew B. , Quan, Annie , Robinson, Phillip J. , McCluskey, Adam
Resource Type: journal article
Date: 2022

The sulfonadyns: a class of aryl sulfonamides inhibiting dynamin I GTPase and clathrin mediated endocytosis are anti-seizure in animal models

Creator: Odell, Luke R. , Jones, Nigel C. , Daniel, James A. , Gorgani, Nick N. , O'Brien, Terence J. , Robinson, Phillip J. , McCluskey, Adam , Chau, Ngoc , Robertson, Mark J. , Ambrus, Joseph I. , Deane, Fiona M. , Young, Kelly A. , Whiting, Ainslie , Xue, Jing , Prichard, Kate
Resource Type: journal article
Date: 2023

In Vitro Activity of Robenidine Analogues NCL259 and NCL265 against Gram-Negative Pathogens

Creator: Pi, Hongfei , Venter, Henrietta , Russell, Cecilia C. , Young, Kelly A. , McCluskey, Adam , Page, Stephen W. , Ogunniyi, Abiodum D. , Trott, Darren J.
Resource Type: journal article
Date: 2022

Gram-Positive and Gram-Negative Antibiotic Activity of Asymmetric and Monomeric Robenidine Analogues

Creator: Russell, Cecilia C. , Stevens, Andrew , McCluskey, Adam , Pi, Hongfei , Khazandi, Manouchehr , Ogunniyi, Abiodun D. , Young, Kelly A. , Baker, Jennifer R. , McCluskey, Siobhann N. , Page, Stephen W. , Trott, Darren J.
Resource Type: journal article
Date: 2018

Discovery of 4,6-bis(2-((E)-benzylidene)hydrazinyl)pyrimidin-2-amine with antibiotic activity

Creator: Russell, Cecillia C. , Stevens, Andrew , McCluskey, Adam , Young, Kelly A. , Baker, Jennifer R. , McCluskey, Siobhann N. , Khazandi, Manouchehr , Pi, Hongfei , Ogunniyi, Abiodun , Page, Stephen W. , Trott, Darren J.
Resource Type: journal article
Date: 2019

Antigiardial Activity of Novel Guanidine Compounds

Creator: Stevens, Andrew J. , Abraham, Rebecca , Young, Kelly A. , Russell, Cecilia C. , McCluskey, Siobhann N. , Baker, Jennifer R. , Rusdi, Bertha , Page, Stephen W. , O'Handley, Ryan , O'Dea, Mark , Abraham, Sam , McCluskey, Adam
Resource Type: journal article
Date: 2022

A flow chemistry approach to norcantharidin analogues

Creator: Tarleton, Mark , Young, Kelly A. , Unicomb, Eli , McCluskey, Siobahnn N. , Robertson, Mark J. , Gordon, Christopher P. , McCluskey, Adam
Resource Type: journal article
Date: 2011

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