The nucleotide-binding domain, leucine-rich repeat protein 3 inflammasome/IL-1 receptor I axis mediates innate, but not adaptive, immune responses after exposure to particulate matter under 10 µm
- Creator: Hirota, Jeremy A. , Gold, Matthew J. , McNagny, Kelly M. , Knight, Darryl A. , Hiebert, Paul R. , Parkinson, Leigh G. , Wee, Tracee , Smith, Dirk , Hansbro, Phil M. , Carlsten, Chris , VanEeden, Stephen , Sin, Don D.
- Resource Type: journal article
- Date: 2015
PM10-stimulated airway epithelial cells activate primary human dendritic cells independent of uric acid: application of an in vitro model system exposing dendritic cells to airway epithelial cell-conditioned media
- Creator: Hirota, Jeremy A. , Alexis, Neil E. , Pui, Mandy , Wong, SzeWing , Fung, Elkie , Hansbro, Phillip , Knight, Darryl , Sin, Don D. , Carlsten, Chris
- Resource Type: journal article
- Date: 2014
The overlap of lung tissue transcriptome of smoke exposed mice with human smoking and COPD
- Creator: Obeidat, Ma’en , Dvorkin-Gheva, Anna , Stampfli, Martin R. , Sin, Don D. , Li, Xuan , Bosse, Yohan , Brandsma, Corry-Anke , Nickle, David C. , Hansbro, Philip M. , Faner, Rosa , Agusti, Alvar , Pare, Peter D.
- Resource Type: journal article
- Date: 2018
IL-4Ra blockade reduces influenza-associated morbidity in a murine model of allergic asthma
- Creator: Shahangian, Kimia , Ngan, David A. , Chen, H. H. Rachel , Oh, Yeni , Tam, Anthony , Wen, Jing , Cheung, Chung , Knight, Darryl A. , Dorscheid, Delbert R. , Hackett, Tillie L. , Hughes, Michael R. , McNagny, Kelly M. , Hirota, Jeremy A. , Niikura, Masahiro , Man, S. F. Paul , Sin, Don D.
- Resource Type: journal article
- Date: 2021
What is asthma - COPD overlap syndrome? Towards a consensus definition from a round table discussion
- Creator: Sin, Don D. , Miravitlles, Marc , Wechsler, Michael E. , Mannino, David M. , Soriano, Joan B. , Price, David , Celli, Bartolome R. , Leung, Janice M. , Nakano, Yasutaka , Park, Hye Yun , Wark, Peter A.
- Resource Type: journal article
- Date: 2016
IL-22 and its receptors are increased in human and experimental COPD and contribute to pathogenesis
- Creator: Starkey, Malcolm R. , Plank, Maximilian W. , Donovan, Chantal , Hansbro, Nicole G. , Nguyen, Duc H. , Nair, Prema Mono , Kim, Richard Y. , Horvat, Jay C. , Kaiko, Gerard E. , Durum, Scott K. , Wark, Peter A. , Sin, Don D. , Casolari, Paolo , Caramori, Gaetano , Adcock, Ian M. , Foster, Paul S. , Hansbro, Philip M. , Papi, Alberto , Pavlidis, Stelios , Guo, Yike , Cameron, Guy J. M. , Haw, Tatt Jhong , Tam, Anthony , Obiedat, Maen
- Resource Type: journal article
- Date: 2019