4-Octyl Itaconate Alleviates Airway Eosinophilic Inflammation by Suppressing Chemokines and Eosinophil Development
- Creator: Yin, Maureen , Wadhwa, Ridhima , Marshall, Jacqueline E. , Gillis, Caitlin M. , Kim, Richard Y. , Dua, Kamal , Palsson-McDermott, Eva M. , Fallon, Padraic G. , Hansbro, Philip M. , O'Neill, Luke A. J.
- Resource Type: journal article
- Date: 2024
Interferon-epsilon is a novel regulator of NK cell responses in the uterus
- Creator: Mayall, Jemma R. , Horvat, Jay C. , de Geus, Eveline D. , Starkey, Malcolm R. , Kim, Richard Y. , Daly, Katie , Goggins, Bridie J. , Keely, Simon , Maltby, Steven , Baldwin, Rennay , Foster, Paul S. , Boyle, Michael J. , Mangan, Niamh E. , Tanwar, Pradeep S. , Huntington, ND , Hertzog, PJ , Hansbro, Philip M. , Chevalier, Anne , McCarthy, Huw , Hampsey, Daniel , Donovan, Chantal , Brown, Alexandra C. , Matthews, Antony Y. , de Weerd, Nicole A.
- Resource Type: journal article
- Date: 2024
Airway and parenchyma transcriptomics in a house dust mite model of experimental asthma
- Creator: Tu, Xiaofan , Gomez, Henry M. , Donovan, Chantal , Kim, Richard Y. , Brown, Alexandra C. , de Jong, Emma , Galvao, Izabela , Faiz, Alen , Bosco, Anthony , Horvat, Jay C. , Hansbro, Philip
- Resource Type: journal article
- Date: 2023
Back to the Eosinophil: Resolvin Spatiotemporal Regulation
- Creator: Donovan, Chantal , Barnes, Jessica L. , Kim, Richard Y.
- Resource Type: journal article
- Date: 2023
Characterization and inhibition of inflammasome responses in severe and non-severe asthma
- Creator: Horvat, Jay C. , Kim, Richard Y. , Weaver, Natasha , Augood, Christopher , Brown, Alexandra C. , Donovan, Chantal , Dupre, Pierrick , Gunawardhana, Lakshitha , Mayall, Jemma R. , Hansbro, Nicole G. , Robertson, Avril A. B. , O'Neill, Luke A. J. , Cooper, Matthew A. , Holliday, Elizabeth G. , Hansbro, Philip M. , Gibson, Peter G.
- Resource Type: journal article
- Date: 2023
Pre-clinical lung squamous cell carcinoma mouse models to identify novel biomarkers and therapeutic interventions
- Creator: Sahu, Priyanka , Donovan, Chantal , Bielefeldt-Ohmann, Helle , Mazilli, Sarah , Caramori, Gaetano , Lyons, J. Guy , Hansbro, Philip M. , Paudel, Keshav Raj , Pickles, Sophie , Chimankar, Vrushali , Kim, Richard Y. , Horvart, Jay C. , Dua, Kamal , Ieni, Antonio , Nucera, Francesco
- Resource Type: journal article
- Date: 2023
RIPK1 kinase-dependent inflammation and cell death contribute to the pathogenesis of COPD
- Creator: Van Eeckhoutte, Hannelore P. , Donovan, Chantal , Beal, Allison M. , Geddes, Brad , Bertin, John , Vanden Berghe, Tom , De Volder, Joyceline , Maes, Tania , Vandenabeele, Peter , Vanaudenaerde, Bart M. , Deforce, Dieter , Škevin, Sonja , Kim, Richard Y. , Van Nieuwerburgh, Filip , Verhamme, FM , Joos, GF , Idrees, S , Schiller, HB , Yildirim, AÖ , Faiz, A , Bertrand, MJM , Brusselle, GG , Hansbro, Philip M. , Conlon, Thomas M. , Bracke, KR , Ansari, Meshal , Khan, Haroon , Jayaraman, Ranjith , Hansbro, Nicole G. , Dondelinger, Yves , Delanghe, Tom
- Resource Type: journal article
- Date: 2023
Smoking and tetramer tryptase accelerate intervertebral disc degeneration by inducing METTL14-mediated DIXDC1 m⁶ modification
- Creator: Tu, Ji , Li, Wentian , Zou, Jun , Diwan, Ashish , Hansbro, Philip M. , Yan, Qi , Bai, Xupeng , Donovan, Chantal , Kim, Richard Y. , Galvao, Izabela , Das, Abhirup , Yang, Cao
- Resource Type: journal article
- Date: 2023
Systemic alterations in neutrophils and their precursors in early-stage chronic obstructive pulmonary disease
- Creator: Kapellos, Theodore S. , Baßler, Kevin , Dudkin, Erica , Frishberg, Amit , de Domenico, Elena , Horne, Arik , Donovan, Chantal , Kim, Richard Y. , Gallego-Ortega, David , Gillett, Tessa E. , Ansari, Meshal , Schulte-Schrepping, Jonas , Fujii, Wataru , Offermann, Nina , Antignano, I , Sivri, B , Lu, W , Eapen, MS , van Uelft, M , Osei-Sarpong, C , van den Berge, M , Donker, HC , Groen, HJM , Nalkurthi, Christina , Sohal, SS , Klein, J , Schreiber, T , Feißt, A , Yildirim, AÖ , Schiller, HB , Nawijn, MC , Becker, M , Händler, K , Beyer, M , Schaar, Anna C. , Capasso, M , Ulas, T , Hasenauer, J , Pizarro, C , Theis, FJ , Hansbro, PM , Skowasch, D , Schultze, JL , Bonaguro, Lorenzo , Pecht, Tal , Galvao, Izabela , Agrawal, Shobhit , Saglam, Adem
- Resource Type: journal article
- Date: 2023
Third-Hand Exposure to E-Cigarette Vapour Induces Pulmonary Effects in Mice
- Creator: Thorpe, Andrew E. , Donovan, Chantal , Kim, Richard Y. , Vindin, Howard J. , Zakarya, Razia , Miyai, Hanna , Chan, Yik L. , van Reyk, David , Chen, Hui , Oliver, Brian G.
- Resource Type: journal article
- Date: 2023
TLR7 promotes smoke-induced experimental lung damage through the activity of mast cell tryptase
- Creator: Liu, Gang , Haw, Tatt Jhong , Hortle, Elinor , Pickles, Sophie , Rojas-Quintero, Joselyn , Estepar, Raul San Jose , Marshall, Jacqueline E. , Kim, Richard Y. , Collison, Adam M. , Mattes, Joerg , Idrees, Sobia , Faiz, Alen , Starkey, Malcolm R. , Hansbro, Nicole G. , Fukui, R , Murakami, Y , Cheng, HS , Tan, NS , Chotirmall, SH , Horvat, Jay C. , Foster, Paul S. , Oliver, BG , Polverino, F , Philp, Ashleigh M. , Ieni, A , Monaco, F , Caramori, G , Sohal, SS , Bracke, KR , Wark, Peter A. , Adcock, IM , Miyake, K , Sin, DD , Hansbro, Philip M. , Pavlidis, Stelios , Nalkurthi, Christina , Nair, Prema M. , Gomez, Henry M. , Hanish, Irwan , Hsu, Alan CY
- Resource Type: journal article
- Date: 2023
Airway and parenchymal transcriptomics in a novel model of asthma and COPD overlap
- Creator: Tu, Xiaofan , Kim, Richard Y. , Loering, Svenja , Nguyen, Duc H. , Nair, Prema Mono , Haw, Tatt Jhong , Alemao, Charlotte A. , Faiz, Alen , Tay, Hock L. , Wark, Peter A. B. , Knight, Darryl A. , Foster, Paul S. , Brown, Alexandra C. , Bosco, Anthony , Horvat, Jay C. , Hansbro, Philip M. , Donovan, Chantal , de Jong, Emma , Jones-Freeman, Bernadette , Ali, Md Khadem , Gomez, Henry M. , Budden, Kurtis F. , Starkey, Malcolm R. , Cameron, Guy J. M.
- Resource Type: journal article
- Date: 2022
Itaconate and itaconate derivatives target JAK1 to suppress alternative activation of macrophages
- Creator: Runtsch, Marah C. , Angiari, Stefano , Mendez, Rui Santalla , Zotta, Alessia , Peace, Christian G. , Walsh, Aoife , Chirillo, Roberta , Hams, Emily , Fallon, Padraic G. , Jayamaran, Ranjith , Dua, Kamal , Brown, Alexandra C. , Hooftman, Alexander , Kim, Richard Y. , Horvat, Jay C. , Hansbro, Philip M. , Wang, C , O'Neill, LAJ , Wadhwa, Ridhima , Zhang, Yanling , Zheng, Yunan , Spina, Joseph S. , Ruzek, Melanie C. , Argiriadi, Maria A. , McGettrick, Anne F.
- Resource Type: journal article
- Date: 2022
Relationship between type 2 cytokine and inflammasome responses in obesity-associated asthma
- Creator: Pinkerton, James W. , Kim, Richard Y. , Baines, Katherine J. , Starkey, Malcolm R. , Kermani, Nazanin Z. , Guo, Yi-Ke , Robertson, Avril A. B. , O'Neill, Luke A. J. , Adcock, Ian M. , Cooper, Matthew A. , Gibson, Peter G. , Wood, Lisa G. , Brown, Alexandra C. , Hansbro, Philip M. , Horvat, Jay C. , Rae, Brittany E. , Donovan, Chantal , Mayall, Jemma R. , Carroll, Olivia R. , Ali, Md. Khadem , Scott, Hayley A. , Berthon, Bronwyn S.
- Resource Type: journal article
- Date: 2022
Asthma-COPD overlap: current understanding and the utility of experimental models
- Creator: Tu, Xiaofan , Donovan, Chantal , Kim, Richard Y. , Wark, Peter A. B. , Horyat, Jay C. , Hansbro, Philip M.
- Resource Type: journal article
- Date: 2021
Investigating the links between lower iron status in pregnancy and respiratory disease in offspring using murine models
- Creator: Gomez, Henry M. , Pillar, Amber L. , Brown, Alexandra C. , Kim, Richard Y. , Ali, Md Khadem , Essilfie, Ama-Tawiah , Vanders, Rebecca , Frazer, David M. , Anderson, Gregory J. , Hansbro, Philip M. , Collison, Adam M. , Jensen, Megan E. , Murphy, Vanessa E. , Johnstone, Daniel M. , Reid, David , Milward, Elizabeth A. , Donovan, Chantal , Horvat, Jay C.
- Resource Type: journal article
- Date: 2021
microRNA-21-mediated SATB1/S100A9/NF-kappa B axis promotes chronic obstructive pulmonary disease pathogenesis
- Creator: Kim, Richard Y. , Sunkara, Krishna P. , Ricciardolo, Fabio L. M. , Di Stefano, Antonino , Haw, Tatt Jhong , Liu, Gang , Ferguson, Angela L. , Palendira, Umamainthan , Wark, Peter A. , Conickx, Griet , Mestdagh, Pieter , Brusselle, Guy G. , Bracke, Ken R. , Caramori, Gaetano , Foster, Paul S. , Horvat, Jay C. , Hansbro, Philip M. , Jarnicki, Andrew G. , Donovan, Chantal , Hsu, Alan C. , Ieni, Antonio , Beckett, Emma L. , Galvão, Izabela , Wijnant, Sara
- Resource Type: journal article
- Date: 2021
T-helper 22 cells develop as a distinct lineage from Th17 cells during bacterial infection and phenotypic stability is regulated by T-bet
- Creator: Barnes, Jessica L. , Plank, Maximilian W. , Hansbro, Philip M. , Keely, Simon , Belz, Gabrielle T. , Tay, Hock L. , Foster, Paul S. , Asquith, Kelly , Maltby, Steven , Sabino, Lorena R. , Kaiko, Gerard E. , Lochrin, Alyssa , Horvat, Jay C. , Mayall, Jemma R. , Kim, Richard Y.
- Resource Type: journal article
- Date: 2021
Critical role for iron accumulation in the pathogenesis of fibrotic lung disease
- Creator: Ali, Md Khadem , Kim, Richard Y. , Borghuis, Theo , Karim, Rafia , Pinkerton, James W. , Aryal, Ritambhara , Heidari, Moones , Martin, Kristy L. , Burgess, Janette K. , Oliver, Brian G. , Trinder, Debbie , Johnstone, Daniel M. , Brown, Alexandra C. , Milward, Elizabeth A. , Hansbro, Philip M. , Horvat, Jay C. , Donovan, Chantal , Vanka, Kanth S. , Mayall, Jemma R. , Liu, Gang , Pillar, Amber L. , Jones-Freeman, Bernadette , Xenaki, Dikaia
- Resource Type: journal article
- Date: 2020
Crucial role for lung iron level and regulation in the pathogenesis and severity of asthma
- Creator: Ali, Md Khadem , Kim, Richard Y. , Donovan, Chantal , Pathinayake, Prabuddha S. , Carroll, Olivia R. , Trinder, Debbie , Tay, Hock L. , Badi, Yusef E. , Kermani, Nazanin Z. , Guo, Yi-Ke , Aryal, Ritambhara , Mumby, Sharon , Brown, Alexandra C. , Pavlidis, Stelios , Adcock, IM , Weaver, Jessica , Xenaki, D , Oliver, BG , Holliday, Elizabeth G. , Foster, Peter S. , Wark, Peter A. , Johnstone, DM , Milward, EA , Mayall, Jemma R. , Hansbro, Philip M. , Horvat, Jay C. , Karim, Rafia , Pinkerton, James W. , Liu, Gang , Martin, Kristy L. , Starkey, Malcolm R. , Pillar, Amber L.
- Resource Type: journal article
- Date: 2020