Airway and parenchymal transcriptomics in a novel model of asthma and COPD overlap
- Creator: Tu, Xiaofan , Kim, Richard Y. , Loering, Svenja , Nguyen, Duc H. , Nair, Prema Mono , Haw, Tatt Jhong , Alemao, Charlotte A. , Faiz, Alen , Tay, Hock L. , Wark, Peter A. B. , Knight, Darryl A. , Foster, Paul S. , Brown, Alexandra C. , Bosco, Anthony , Horvat, Jay C. , Hansbro, Philip M. , Donovan, Chantal , de Jong, Emma , Jones-Freeman, Bernadette , Ali, Md Khadem , Gomez, Henry M. , Budden, Kurtis F. , Starkey, Malcolm R. , Cameron, Guy J. M.
- Resource Type: journal article
- Date: 2022
Itaconate and itaconate derivatives target JAK1 to suppress alternative activation of macrophages
- Creator: Runtsch, Marah C. , Angiari, Stefano , Mendez, Rui Santalla , Zotta, Alessia , Peace, Christian G. , Walsh, Aoife , Chirillo, Roberta , Hams, Emily , Fallon, Padraic G. , Jayamaran, Ranjith , Dua, Kamal , Brown, Alexandra C. , Hooftman, Alexander , Kim, Richard Y. , Horvat, Jay C. , Hansbro, Philip M. , Wang, C , O'Neill, LAJ , Wadhwa, Ridhima , Zhang, Yanling , Zheng, Yunan , Spina, Joseph S. , Ruzek, Melanie C. , Argiriadi, Maria A. , McGettrick, Anne F.
- Resource Type: journal article
- Date: 2022
Relationship between type 2 cytokine and inflammasome responses in obesity-associated asthma
- Creator: Pinkerton, James W. , Kim, Richard Y. , Baines, Katherine J. , Starkey, Malcolm R. , Kermani, Nazanin Z. , Guo, Yi-Ke , Robertson, Avril A. B. , O'Neill, Luke A. J. , Adcock, Ian M. , Cooper, Matthew A. , Gibson, Peter G. , Wood, Lisa G. , Brown, Alexandra C. , Hansbro, Philip M. , Horvat, Jay C. , Rae, Brittany E. , Donovan, Chantal , Mayall, Jemma R. , Carroll, Olivia R. , Ali, Md. Khadem , Scott, Hayley A. , Berthon, Bronwyn S.
- Resource Type: journal article
- Date: 2022
Asthma-COPD overlap: current understanding and the utility of experimental models
- Creator: Tu, Xiaofan , Donovan, Chantal , Kim, Richard Y. , Wark, Peter A. B. , Horyat, Jay C. , Hansbro, Philip M.
- Resource Type: journal article
- Date: 2021
Investigating the links between lower iron status in pregnancy and respiratory disease in offspring using murine models
- Creator: Gomez, Henry M. , Pillar, Amber L. , Brown, Alexandra C. , Kim, Richard Y. , Ali, Md Khadem , Essilfie, Ama-Tawiah , Vanders, Rebecca , Frazer, David M. , Anderson, Gregory J. , Hansbro, Philip M. , Collison, Adam M. , Jensen, Megan E. , Murphy, Vanessa E. , Johnstone, Daniel M. , Reid, David , Milward, Elizabeth A. , Donovan, Chantal , Horvat, Jay C.
- Resource Type: journal article
- Date: 2021
microRNA-21-mediated SATB1/S100A9/NF-kappa B axis promotes chronic obstructive pulmonary disease pathogenesis
- Creator: Kim, Richard Y. , Sunkara, Krishna P. , Ricciardolo, Fabio L. M. , Di Stefano, Antonino , Haw, Tatt Jhong , Liu, Gang , Ferguson, Angela L. , Palendira, Umamainthan , Wark, Peter A. , Conickx, Griet , Mestdagh, Pieter , Brusselle, Guy G. , Bracke, Ken R. , Caramori, Gaetano , Foster, Paul S. , Horvat, Jay C. , Hansbro, Philip M. , Jarnicki, Andrew G. , Donovan, Chantal , Hsu, Alan C. , Ieni, Antonio , Beckett, Emma L. , Galvão, Izabela , Wijnant, Sara
- Resource Type: journal article
- Date: 2021
T-helper 22 cells develop as a distinct lineage from Th17 cells during bacterial infection and phenotypic stability is regulated by T-bet
- Creator: Barnes, Jessica L. , Plank, Maximilian W. , Hansbro, Philip M. , Keely, Simon , Belz, Gabrielle T. , Tay, Hock L. , Foster, Paul S. , Asquith, Kelly , Maltby, Steven , Sabino, Lorena R. , Kaiko, Gerard E. , Lochrin, Alyssa , Horvat, Jay C. , Mayall, Jemma R. , Kim, Richard Y.
- Resource Type: journal article
- Date: 2021
Critical role for iron accumulation in the pathogenesis of fibrotic lung disease
- Creator: Ali, Md Khadem , Kim, Richard Y. , Borghuis, Theo , Karim, Rafia , Pinkerton, James W. , Aryal, Ritambhara , Heidari, Moones , Martin, Kristy L. , Burgess, Janette K. , Oliver, Brian G. , Trinder, Debbie , Johnstone, Daniel M. , Brown, Alexandra C. , Milward, Elizabeth A. , Hansbro, Philip M. , Horvat, Jay C. , Donovan, Chantal , Vanka, Kanth S. , Mayall, Jemma R. , Liu, Gang , Pillar, Amber L. , Jones-Freeman, Bernadette , Xenaki, Dikaia
- Resource Type: journal article
- Date: 2020
Crucial role for lung iron level and regulation in the pathogenesis and severity of asthma
- Creator: Ali, Md Khadem , Kim, Richard Y. , Donovan, Chantal , Pathinayake, Prabuddha S. , Carroll, Olivia R. , Trinder, Debbie , Tay, Hock L. , Badi, Yusef E. , Kermani, Nazanin Z. , Guo, Yi-Ke , Aryal, Ritambhara , Mumby, Sharon , Brown, Alexandra C. , Pavlidis, Stelios , Adcock, IM , Weaver, Jessica , Xenaki, D , Oliver, BG , Holliday, Elizabeth G. , Foster, Peter S. , Wark, Peter A. , Johnstone, DM , Milward, EA , Mayall, Jemma R. , Hansbro, Philip M. , Horvat, Jay C. , Karim, Rafia , Pinkerton, James W. , Liu, Gang , Martin, Kristy L. , Starkey, Malcolm R. , Pillar, Amber L.
- Resource Type: journal article
- Date: 2020
Disease-associated gut microbiome and metabolome changes in patients with chronic obstructive pulmonary disease
- Creator: Bowerman, Kate L. , Rehman, Saima Firdous , Yang, Ian A. , Wark, Peter A. , Hugenholtz, Philip , Hansbro, Philip M. , Vaughan, Annalicia , Lachner, Nancy , Budden, Kurtis F. , Kim, Richard Y. , Wood, David L. A. , Gellatly, Shaan L. , Shukla, Shakti D. , Wood, Lisa G.
- Resource Type: journal article
- Date: 2020
Emerging therapeutic targets and preclinical models for severe asthma
- Creator: Galvao, Izabela , Kim, Richard Y. , Shen, Sijie , Budden, Kurtis F. , Vieira, Angélica T. , Hansbro, Philip M.
- Resource Type: journal article
- Date: 2020
Human beta-defensin-2 suppresses key features of asthma in murine models of allergic airways disease
- Creator: Pinkerton, James W. , Kim, Richard Y. , Nordkild, Peter , Horvat, Jay C. , Jensen, Benjanim A. H. , Wehkamp, Jan , Hansbro, Philip M. , Koeninger, Louis , Armbruster, Nicole S. , Hansbro, Nicole G. , Brown, Alexandra C. , Jayaraman, Ranjith , Shen, Sijie , Malek, Nisar , Cooper, Matthew A.
- Resource Type: journal article
- Date: 2020
Pathophysiological regulation of lung function by the free fatty acid receptor FFA4
- Creator: Prihandoko, Rudi , Kaur, Davinder , Alharbi, Abdulrahman Ghali M. , Kim, Richard Y. , Lowe, Jack G. , Hansbro, Philip M. , Chung, Kian Fan , Brightling, Christopher E. , Milligan, Graeme , Tobin, Andrew B. , Wiegman, Coen H. , Alvarez-Curto, Elisa , Donovan, Chantal , Chachi, Latifa , Ulven, Trond , Tyas, Martha R. , Euston, Eloise , Dong, Zhaoyang
- Resource Type: journal article
- Date: 2020
The role of the microbiome and the NLRP3 inflammasome in the gut and lung
- Creator: Donovan, Chantal , Liu, Gang , Yang, Ian A. , Hansbro, Philip M. , Shen, Sj , Marshall, Jacqueline E. , Kim, Richard Y. , Alemao, Charlotte A. , Budden, Kurtis F. , Choi, Jaesung P. , Kohonen-Corish, Maija , El-Omar, Emad M.
- Resource Type: journal article
- Date: 2020
Cellular mechanisms underlying steroid-resistant asthma
- Creator: Wadhwa, Ridhima , Dua, Kamal , Adcock, Ian M. , Horvat, Jay C. , Kim, Richard Y. , Hansbro, Philip M.
- Resource Type: journal article
- Date: 2019
IL-22 and its receptors are increased in human and experimental COPD and contribute to pathogenesis
- Creator: Starkey, Malcolm R. , Plank, Maximilian W. , Donovan, Chantal , Hansbro, Nicole G. , Nguyen, Duc H. , Nair, Prema Mono , Kim, Richard Y. , Horvat, Jay C. , Kaiko, Gerard E. , Durum, Scott K. , Wark, Peter A. , Sin, Don D. , Casolari, Paolo , Caramori, Gaetano , Adcock, Ian M. , Foster, Paul S. , Hansbro, Philip M. , Papi, Alberto , Pavlidis, Stelios , Guo, Yike , Cameron, Guy J. M. , Haw, Tatt Jhong , Tam, Anthony , Obiedat, Maen
- Resource Type: journal article
- Date: 2019
Polycomb repressive complex 2 is a critical mediator of allergic inflammation
- Creator: Keenan, Christine R. , Iannarella, Nadia , Garnham, Alexandra L. , Brown, Alexandra C. , Kim, Richard Y. , Horvat, Jay C. , Hansbro, Philip M. , Nutt, Stephen L. , Allan, Rhys S.
- Resource Type: journal article
- Date: 2019
Roles for T/B lymphocytes and ILC2s in experimental chronic obstructive pulmonary disease
- Creator: Donovan, Chantal , Starkey, Malcolm R. , Horvat, Jay C. , Wark, Peter A. , Foster, Paul S. , McKenzie, Andrew N. J. , Hansbro, Philip M. , Kim, Richard Y. , Rana, Batika M. J. , Barlow, Jillian L. , Jones, Bernadette , Haw, Tatt Jhong , Mono Nair, Prema , Budden, Kurtis , Cameron, Guy J. M.
- Resource Type: journal article
- Date: 2019
Chronic cigarette smoke exposure induces systemic hypoxia that drives intestinal dysfunction
- Creator: Fricker, Michael , Goggins, Bridie J. , Talley, Nicholas J. , Walker, Marjorie M. , Keely, Simon , Hansbro, Philip M. , Mateer, Sean , Jones, Bernadette , Kim, Richard Y. , Gellatly, Shaan L. , Jarnicki, Andrew G. , Powell, Nicholas , Oliver, Brian G. , Radford-Smith, Graham
- Resource Type: journal article
- Date: 2018
IL-6 drives neutrophil-mediated pulmonary inflammation associated with bacteremia in murine models of colitis
- Creator: Mateer, Sean W. , Mathe, Andrea , Kim, Richard Y. , Minahan, Kyra , Walker, Marjorie M. , Callister, Robert C. , Foster, Paul S. , Horvat, Jay C. , Hansbro, Philip M. , Keely, Simon , Bruce, Jessica , Liu, Gang , Maltby, Steven , Fricker, Michael , Goggins, Bridie J. , Tay, Hock L. , Marks, Ellen , Burns, Grace
- Resource Type: journal article
- Date: 2018