Critical role for iron accumulation in the pathogenesis of fibrotic lung disease
- Creator: Ali, Md Khadem , Kim, Richard Y. , Borghuis, Theo , Karim, Rafia , Pinkerton, James W. , Aryal, Ritambhara , Heidari, Moones , Martin, Kristy L. , Burgess, Janette K. , Oliver, Brian G. , Trinder, Debbie , Johnstone, Daniel M. , Brown, Alexandra C. , Milward, Elizabeth A. , Hansbro, Philip M. , Horvat, Jay C. , Donovan, Chantal , Vanka, Kanth S. , Mayall, Jemma R. , Liu, Gang , Pillar, Amber L. , Jones-Freeman, Bernadette , Xenaki, Dikaia
- Resource Type: journal article
- Date: 2020
Crucial role for lung iron level and regulation in the pathogenesis and severity of asthma
- Creator: Ali, Md Khadem , Kim, Richard Y. , Donovan, Chantal , Pathinayake, Prabuddha S. , Carroll, Olivia R. , Trinder, Debbie , Tay, Hock L. , Badi, Yusef E. , Kermani, Nazanin Z. , Guo, Yi-Ke , Aryal, Ritambhara , Mumby, Sharon , Brown, Alexandra C. , Pavlidis, Stelios , Adcock, IM , Weaver, Jessica , Xenaki, D , Oliver, BG , Holliday, Elizabeth G. , Foster, Peter S. , Wark, Peter A. , Johnstone, DM , Milward, EA , Mayall, Jemma R. , Hansbro, Philip M. , Horvat, Jay C. , Karim, Rafia , Pinkerton, James W. , Liu, Gang , Martin, Kristy L. , Starkey, Malcolm R. , Pillar, Amber L.
- Resource Type: journal article
- Date: 2020
Advances in Respiratory Physiology in Mouse Models of Experimental Asthma
- Creator: Carroll, Olivia R. , Pillar, Amber L. , Brown, Alexandra C. , Feng, Min , Chen, Hui , Donovan, Chantal
- Resource Type: journal article
- Date: 2023
Aim2 suppresses cigarette smoke-induced neutrophil recruitment, neutrophil caspase-1 activation and anti-Ly6G-mediated neutrophil depletion
- Creator: Donovan, Chantal , Kim, Richard Y , Khan, Haroon , Pickles, Sophie , Sahu, Priyanka , Chimankar, Vrushali , Tu, Xiaofan , Ali, Md Khadem , Mayall, Jemma R. , Nguyen, Duc H. , Budden, Kurtis F. , Kumar, Vinod , Galvao, Izabela , Wark, Peter A. B. , Horvat, Jay C. , Hansbro, Philip M. , Ab Wark, P , Oliver, BG , Horvat, JC , Hansbro, PM , Jarnicki, Andrew G. , Brown, Alexandra C. , Jones-Freeman, Bernadette , Gomez, Henry M. , Wadhwa, Ridhima , Hortle, Elinor , Jayaraman, Ranjith
- Resource Type: journal article
- Date: 2022
Investigating the links between lower iron status in pregnancy and respiratory disease in offspring using murine models
- Creator: Gomez, Henry M. , Pillar, Amber L. , Brown, Alexandra C. , Kim, Richard Y. , Ali, Md Khadem , Essilfie, Ama-Tawiah , Vanders, Rebecca , Frazer, David M. , Anderson, Gregory J. , Hansbro, Philip M. , Collison, Adam M. , Jensen, Megan E. , Murphy, Vanessa E. , Johnstone, Daniel M. , Reid, David , Milward, Elizabeth A. , Donovan, Chantal , Horvat, Jay C.
- Resource Type: journal article
- Date: 2021
Characterization and inhibition of inflammasome responses in severe and non-severe asthma
- Creator: Horvat, Jay C. , Kim, Richard Y. , Weaver, Natasha , Augood, Christopher , Brown, Alexandra C. , Donovan, Chantal , Dupre, Pierrick , Gunawardhana, Lakshitha , Mayall, Jemma R. , Hansbro, Nicole G. , Robertson, Avril A. B. , O'Neill, Luke A. J. , Cooper, Matthew A. , Holliday, Elizabeth G. , Hansbro, Philip M. , Gibson, Peter G.
- Resource Type: journal article
- Date: 2023
Polycomb repressive complex 2 is a critical mediator of allergic inflammation
- Creator: Keenan, Christine R. , Iannarella, Nadia , Garnham, Alexandra L. , Brown, Alexandra C. , Kim, Richard Y. , Horvat, Jay C. , Hansbro, Philip M. , Nutt, Stephen L. , Allan, Rhys S.
- Resource Type: journal article
- Date: 2019
Role for NLRP3 inflammasome-mediated, IL-1ß-dependent responses in severe, steroid-resistant asthma
- Creator: Kim, Richard Y. , Pinkerton, James W. , Hirota, Jeremy A. , Wood, Lisa G. , Simpson, Jodie L. , Knight, Darryl A. , Wark, Peter A. , Gibson, Peter G. , O'Neill, Luke A. J. , Cooper, Matthew A. , Horvat, Jay C. , Hansbro, Philip M. , Essilfie, Ama T. , Robertson, Avril A. B. , Baines, Katherine J. , Brown, Alexandra C. , Mayall, Jemma R. , Ali, M. Khadem , Starkey, Malcolm R. , Hansbro, Nicole G.
- Resource Type: journal article
- Date: 2017
Visualization of endogenous p27 and Ki67 reveals the importance of a c-Myc-driven metabolic switch in promoting survival of quiescent cancer cells
- Creator: La, Ting , Chen, Song , Brown, Alexandra C. , Zhang, Didi , Dong, Qihan , Wang, Jenny Y. , Cao, Huixia , Liu, Tao , Thorne, Rick F. , Shao, Feng-Min , Zhang, Xu Dong , Jin, Lei , Guo, Tao , Zhao, Xiao Hong , Teng, Liu , Li, Dandan , Carnell, Michael , Zhang, Yuan Yuan , Feng, Yu Chen , Cole, Nicole
- Resource Type: journal article
- Date: 2021
Airway remodelling and inflammation in asthma are dependent on the extracellular matrix protein fibulin-1c
- Creator: Liu, Gang , Cooley, Marion A. , Tay, Hock , Foster, Paul S. , Wark, Peter A. , Horvat, Jay C. , Bourke, Jane E. , Grainge, Chris L. , Argraves, W. Scott , Oliver, Brian G. , Knight, Darryl A. , Burgess, Janette K. , Nair, Prema M. , Hansbro, Philip M. , Donovan, Chantal , Hsu, Alan C. , Jarnicki, Andrew G. , Haw, Tatt Jhong , Hansbro, Nicole G. , Ge, Qi , Brown, Alexandra C.
- Resource Type: journal article
- Date: 2017
Glycemic variability in diabetes increases the severity of influenza
- Creator: Marshall, Rebecca J. , Armart, Pornthida , Gallo, Linda A. , Short, Kirsty R. , Hulme, Katina D. , Chew, Keng Ylh , Brown, Alexandra C. , Hansbro, Philip M. , Bloxham, Conor J. , Flint, Melanie , Ronacher, Katharina , Bielefeldt-Ohmann, Helle
- Resource Type: journal article
- Date: 2020
Interferon-epsilon is a novel regulator of NK cell responses in the uterus
- Creator: Mayall, Jemma R. , Horvat, Jay C. , de Geus, Eveline D. , Starkey, Malcolm R. , Kim, Richard Y. , Daly, Katie , Goggins, Bridie J. , Keely, Simon , Maltby, Steven , Baldwin, Rennay , Foster, Paul S. , Boyle, Michael J. , Mangan, Niamh E. , Tanwar, Pradeep S. , Huntington, ND , Hertzog, PJ , Hansbro, Philip M. , Chevalier, Anne , McCarthy, Huw , Hampsey, Daniel , Donovan, Chantal , Brown, Alexandra C. , Matthews, Antony Y. , de Weerd, Nicole A.
- Resource Type: journal article
- Date: 2024
Endoplasmic reticulum-unfolded protein response signalling is altered in severe eosinophilic and neutrophilic asthma
- Creator: Pathinayake, Prabuddha S. , Waters, David W. , Gibson, Peter G. , Hansbro, Philip M. , Wark, Peter A. B. , Nichol, Kristy S. , Brown, Alexandra C. , Reid, Andrew T. , Hsu, Alan Chen-Yu , Horvat, Jay C. , Wood, Lisa G. , Baines, Katherine J. , Simpson, Jodie L.
- Resource Type: journal article
- Date: 2021
Relationship between type 2 cytokine and inflammasome responses in obesity-associated asthma
- Creator: Pinkerton, James W. , Kim, Richard Y. , Baines, Katherine J. , Starkey, Malcolm R. , Kermani, Nazanin Z. , Guo, Yi-Ke , Robertson, Avril A. B. , O'Neill, Luke A. J. , Adcock, Ian M. , Cooper, Matthew A. , Gibson, Peter G. , Wood, Lisa G. , Brown, Alexandra C. , Hansbro, Philip M. , Horvat, Jay C. , Rae, Brittany E. , Donovan, Chantal , Mayall, Jemma R. , Carroll, Olivia R. , Ali, Md. Khadem , Scott, Hayley A. , Berthon, Bronwyn S.
- Resource Type: journal article
- Date: 2022
Human beta-defensin-2 suppresses key features of asthma in murine models of allergic airways disease
- Creator: Pinkerton, James W. , Kim, Richard Y. , Nordkild, Peter , Horvat, Jay C. , Jensen, Benjanim A. H. , Wehkamp, Jan , Hansbro, Philip M. , Koeninger, Louis , Armbruster, Nicole S. , Hansbro, Nicole G. , Brown, Alexandra C. , Jayaraman, Ranjith , Shen, Sijie , Malek, Nisar , Cooper, Matthew A.
- Resource Type: journal article
- Date: 2020
Generation of cardio-protective antibodies after pneumococcal polysaccharide vaccine: Early results from a randomised controlled trial
- Creator: Ren, Shu , Hansbro, Philip M. , Srikusalanukul, Wichat , Horvat, Jay C. , Hunter, Tegan , Brown, Alexandra C. , Peel, Roseanne , Faulkner, Jack , Evans, Tiffany-Jane , Li, Shu Chuen , Newby, David , Hure, Alexis , Abhayaratna, Walter P. , Tsimikas, Sotirios , Gonen, Ayelet , Witztum, Joseph L. , Attia, John
- Resource Type: journal article
- Date: 2022
Itaconate and itaconate derivatives target JAK1 to suppress alternative activation of macrophages
- Creator: Runtsch, Marah C. , Angiari, Stefano , Mendez, Rui Santalla , Zotta, Alessia , Peace, Christian G. , Walsh, Aoife , Chirillo, Roberta , Hams, Emily , Fallon, Padraic G. , Jayamaran, Ranjith , Dua, Kamal , Brown, Alexandra C. , Hooftman, Alexander , Kim, Richard Y. , Horvat, Jay C. , Hansbro, Philip M. , Wang, C , O'Neill, LAJ , Wadhwa, Ridhima , Zhang, Yanling , Zheng, Yunan , Spina, Joseph S. , Ruzek, Melanie C. , Argiriadi, Maria A. , McGettrick, Anne F.
- Resource Type: journal article
- Date: 2022
Effect of obesity on airway and systemic inflammation in adults with asthma: a systematic review and meta-analysis
- Creator: Scott, Hayley A. , Ng, Shawn H. M. , McLoughlin, Rebecca F. , Valkenborghs, Sarah R. , Nair, Parameswaran , Brown, Alexandra C. , Carroll, Olivia R. , Horvat, Jay C. , Wood, Lisa G.
- Resource Type: journal article
- Date: 2023
COPD is characterized by increased detection of Haemophilus influenzae, Streptococcus pneumoniae and a deficiency of Bacillus species
- Creator: Simpson, Jodie L. , Baines, Katherine J. , Horvat, Jay C. , Essilfie, Ama-Tawiah , Brown, Alexandra C. , Tooze, Melinda , McDonald, Vanessa M. , Gibson, Peter G. , Hansbro, Philip M.
- Resource Type: journal article
- Date: 2016
PD-L1 promotes early-life chlamydia respiratory infection-induced severe allergic airway disease
- Creator: Starkey, Malcolm R. , Nguyen, Duc H. , Brown, Alexandra C. , Essilfie, Ama-Tawiah , Kim, Richard Y. , Yagita, Hideo , Horvat, Jay C. , Hansbro, Philip M.
- Resource Type: journal article
- Date: 2016