PI3K/mTOR is a therapeutically targetable genetic dependency in diffuse intrinsic pontine glioma
- Creator: Duchatel, Ryan J. , Jackson, Evangeline R. , Kearney, Padraic S. , Jamaluddin, M. Fairuz B. , Douglas, Alicia M. , Beitaki, Tyrone , McEwen, Holly P. , Persson, Mika L. , Hocke, Emily A. , Jain, Vaibhav , Aksu, Michael , Manning, Elizabeth E. , Parackal, Sarah G. , Murray, Heather C. , Verrills, Nicole M. , Hua, Susan , Cairns, Murray J. , Alvaro, Frank , Dayas, Christopher V. , Dun, Matthew D. , Hua, S , de Bock, CE , Colino-Sanguino, Y , Kiltschewskij, Dylan , Valdes-Mora, F , Tsoli, M , Ziegler, DS , Cairns, MJ , Raabe, EH , Vitanza, NA , Hulleman, E , Phoenix, TN , Koschmann, C , Alvaro, F , Findlay, Izac J. , Dayas, CV , Tinkle, CL , Wheeler, H , Whittle, JR , Eisenstat, DD , Firestein, R , Mueller, S , Valvi, S , Hansford, JR , Ashley, DM , Mannan, Abdul , Gregory, SG , Kilburn, LB , Nazarian, J , Cain, JE , Dun, MD , Staudt, Dilana E. , Thomas, Bryce C. , Germon, Zacary P. , Laternser, Sandra
- Resource Type: journal article
- Date: 2024
Blockade of ROS production inhibits oncogenic signaling in acute myeloid leukemia and amplifies response to precision therapies
- Creator: Germon, Zacary P. , Sillar, Jonathan R. , McLachlan, Tabitha , Schjenken, John E. , Skerrett-Byrne, David A. , Huang, Honggang , Melo-Braga, Marcella N. , Plank, Maximillan W. , Alvaro, Frank , Chamberlain, Janis , De Iuliis, Geoff , Aitken, R. John , Mannan, Abdul , Nixon, Brett , Wei, AH , Enjeti, Anoop K. , Huang, Y , Lock, RB , Larsen, MR , Lee, Heather , Vaghjiani, V , Cain, JE , de Bock, CE , Duchatel, Ryan J. , Verrills, Nicole M. , Dun, Matthew D. , Staudt, Dilana , Murray, Heather C. , Findlay, Izac J. , Jackson, Evangeline R. , McEwen, Holly P. , Douglas, Alicia M.
- Resource Type: journal article
- Date: 2023
Shwachman-Bodian-Diamond syndrome (SBDS) protein is a direct inhibitor of protein phosphatase 2A (PP2A) activity and overexpressed in acute myeloid leukaemia
- Creator: Dun, Matthew D. , Mannan, Abdul , Germon, Zacary , Faulkner, Sam , Chi, Mengna , Skerrett-Byrne, David , Murray, Heather C. , Flanagan, Hayley , Almazi, Juhura G. , Hondermarck, Hubert , Nixon, Brett , De Iuliis, Geoff , Rigby, Callum J. , Chamberlain, J , Alvaro, F , de Bock, CE , Morris, JC , Enjeti, Anoop K. , Verrills, Nicole M. , Butler, Stephen , Toop, Hamish D. , Beck, Dominik , Connerty, Patrick , Sillar, Jonathan , Kahl, Richard G. S. , Duchatel, Ryan J.
- Resource Type: journal article
- Date: 2020