Genome-wide analysis in over 1 million individuals of European ancestry yields improved polygenic risk scores for blood pressure traits
- Creator: Keaton, Jacob M. , Kamali, Zoha , Young, William J. , Lehtimäki, T , Raitakari, OT , Johnson, AD , Newton-Cheh, C , Brown, MJ , Dominiczak, AF , Sever, PJ , Poulter, N , Chambers, JC , Elosua, R , Traylor, Matthew , Siscovick, D , Esko, T , Metspalu, A , Strawbridge, RJ , Laakso, M , Hamsten, A , Hottenga, J-J , de Geus, E , Morris, AD , Palmer, CNA , Giri, Ayush , Nolte, IM , Milaneschi, Y , Marten, J , Wright, A , Zeggini, E , Howson, JMM , O'Donnell, CJ , Spector, T , Nalls, MA , Simonsick, EM , Zheng, Zhili , Liu, Y , van Duijn, CM , Butterworth, AS , Danesh, JN , Menni, C , Wareham, NJ , Khaw, K-T , Sun, YV , Wilson, PWF , Cho, K , Zeng, Jian , Visscher, PM , Denny, JC , Million Veteran Program, , Lifelines Cohort Study, , CHARGE consortium, , ICBP Consortium, , Levy, D , Edwards, TL , Munroe, PB , Snieder, H , Chasman, Daniel I. , Warren, HR , Morris, Andrew P. , Caulfield, Mark J. , Hwang, Shih-Jen , Kooner, Jaspal S. , Xie, Tian , Attia, John R. , Attia, JR , Morrison, AC , Loos, RJF , Kristiansson, K , Schmidt, R , Hicks, AA , Pramstaller, PP , Nelson, CP , Samani, NJ , Vaez, Ahmad , Risch, L , Gyllensten, U , Melander, O , Riese, H , Wilson, JF , Campbell, H , Rich, SS , Psaty, BM , Lu, Y , Rotter, JI , Williams, Ariel , Guo, X , Rice, KM , Vollenweider, P , Sundström, J , Langenberg, C , Tobin, MD , Giedraitis, V , Luan, J , Tuomilehto, J , Kutalik, Z , Goleva, Slavina B. , Ripatti, S , Salomaa, V , Girotto, G , Trompet, S , Jukema, JW , van der Harst, P , Ridker, PM , Giulianini, F , Vitart, V , Goel, A , Ani, Alireza , Watkins, H , Harris, SE , Deary, IJ , van der Most, PJ , Oldehinkel, AJ , Keavney, BD , Hayward, C , Campbell, A , Boehnke, M , Scott, LJ , Evangelou, Evangelos , Boutin, T , Mamasoula, C , Järvelin, M-R , Peters, A , Gieger, C , Lakatta, EG , Cucca, F , Hui, J , Knekt, P , Enroth, S , Hellwege, Jacklyn N. , De Borst, MH , Polašek, O , Concas, MP , Catamo, E , Cocca, M , Li-Gao, R , Hofer, E , Schmidt, H , Spedicati, B , Waldenberger, M , Yengo, Loic , Strachan, DP , Laan, M , Teumer, A , Dörr, M , Gudnason, V , Cook, JP , Ruggiero, D , Kolcic, I , Boerwinkle, E , Traglia, M
- Resource Type: journal article
- Date: 2024
Genome analyses of >200,000 individuals identify 58 loci for chronic inflammation and highlight pathways that link inflammation and complex disorders
- Creator: Ligthart, Symen , Vaez, Ahmad , Võsa, Urmo , Stathopoulou, Maria G. , de Vries, Paul S. , Prins, Bram P. , Van der Most, Peter J. , Tanaka, Toshiko , Naderi, Elnaz , Rose, Lynda M. , Wu, Ying , Karlsson, Robert , Barbalic, Maja , Lin, Honghuang , Pool, René , Zhu, Gu , Macé, Aurélien , Sidore, Carlo , Trompet, Stella , Mangino, Massimo , Sabater-Lleal, Maria , Oldmeadow, Christopher , Holliday, Elizabeth G. , Attia, John R. , Scott, Rodney J. , McEvoy, Mark
- Resource Type: journal article
- Date: 2018
Novel blood pressure locus and gene discovery using genome-wide association study and expression data sets from blood and the kidney
- Creator: Wain, Louise V. , Vaez, Ahmad , Verwoert, Germaine C. , Hottenga, Jouke-Jan , Strawbridge, Rona J. , Esko, Tonu , Arking, Dan E. , Hwang, Shih-Jen , Guo, Xiuqing , Kutalik, Zoltan , Trompet, Stella , Shrine, Nick , Jansen, Rick , Oldmeadow, Christopher , Scott, Rodney , Joehanes, Roby , van Der Most, Peter J. , Erzurumluoglu, A. Mesut , O'Reilly, Paul F. , Cabrera, Claudia P. , Warren, Helen R. , Rose, Lynda M.
- Resource Type: journal article
- Date: 2017
Genome-wide analysis identifies 12 loci influencing human reproductive behavior
- Creator: Barban, Nicola , Jansen, Rick , de Vlaming, Ronald , Vaez, Ahmad , Mandemakers, Jornt J. , Tropf, Felix C. , Shen, Xia , Wilson, James F. , Chasman, Daniel I. , Nolte, Ilja M. , Tragante, Vinicius , van der Laan, Sander W. , Perry, John R. B. , Kong, Augustine , BIOS Consortium , Ahluwalia, Tarunveer S. , Albrecht, Eva , Yerges-Armstrong, Laura , Atzmon, Gil , Auro, Kirsi , Ayers, Kristin , Bakshi, Andrew , Ben-Avraham, Danny , Berger, Klaus , Bergman, Aviv , Bertram, Lars , Bielak, Lawrence F. , Bjornsdottir, Gyda , Bonder, Marc Jan , Broer, Linda , Bui, Minh , Barbieri, Caterina , Cavadino, Alana , Chavarro, Jorge E. , Turman, Constance , Concas, Maria Pina , Cordell, Heather J. , Davies, Gail , Eibich, Peter , Eriksson, Nicholas , Esko, Tõnu , Eriksson, Joel , Falahi, Fahimeh , Felix, Janine F. , Fontana, Mark Alan , Franke, Lude , Gandin, Ilaria , Gaskins, Audrey J. , Gieger, Christian , Gunderson, Erica P. , Guo, Xiuqing , Hayward, Caroline , He, Chunyan , Hofer, Edith , Huang, Hongyang , Joshi, Peter K. , Kanoni, Stavroula , Karlsson, Robert , Kiechl, Stefan , Kifley, Annette , Kluttig, Alexander , Kraft, Peter , Lagou, Vasiliki , Lecoeur, Cecile , Lahti, Jari , Li-Gao, Ruifang , Lind, Penelope A. , Liu, Tian , Makalic, Enes , Mamasoula, Crysovalanto , Matteson, Lindsay , Mbarek, Hamdi , McArdle, Patrick F. , Holliday, Elizabeth G.
- Resource Type: journal article
- Date: 2016
Investigating the causal relationship of C-reactive protein with 32 complex somatic and psychiatric outcomes: a large-scale cross-consortium mendelian randomization study
- Creator: Prins, Bram P. , Abbasi, Ali , Valdes, Ana M. , Bras, Jose , Shatunov, Aleksey , Lu, Chen , Han, Buhm , Raychaudhuri, Soumya , Bevan, Steve , Mayes, Maureen D. , Tsoi, Lam C. , Evangelou, Evangelos , Wong, Anson , Nair, Rajan P. , Grant, Stuan F. A. , Polychronakos, Constantin , Radstake, Timothy R. D. , van Heel, David A. , Dunstan, Melanie L. , Wood, Nicholas W. , Al-Chalabi, Ammar , Dehghan, Abbas , Hakonarson, Hakon , Vaez, Ahmad , Markus, Hugh S. , Elder, James T. , Knight, Jo , Arking, Dan E. , Spector, Timothy D. , Koeleman, Bobby P. C. , van Duijn, Cornelia M. , Martin, Javier , Morris, Andrew P. , Weersma, Rinse K. , Nolte, Ilja , Wijmenga, Cisca , Munroe, Patricia B. , Perry, John R. B. , Pouget, Jennie G. , Jamshidi, Yalda , Snieder, Harold , Alizadeh, Behrooz Z. , Tooney, Paul , Franceschini, Nora , Stuart, Philip E. , Guterriez Achury, Javier , Mistry, Vanisha , Bradfield, Jonathan P.
- Resource Type: journal article
- Date: 2016