Borylated 2,3,4,5-Tetrachlorophthalimide and Their 2,3,4,5-Tetrachlorobenzamide Analogues: Synthesis, Their Glycosidase Inhibition and Anticancer Properties in View to Boron Neutron Capture Therapy
- Creator: Campkin, David M. , Shimadate, Yuna , Bartholomew, Barbara , Bernhardt, Paul V. , Nash, Robert J. , Sakoff, Jennette A. , Kato, Atsushi , Simone, Michela I.
- Resource Type: journal article
- Date: 2022
Recent results from non-basic glycosidase inhibitors: How structural diversity can inform general strategies for improving inhibition potency
- Creator: Simone, Michela I. , Wood, Adam , Campkin, David , Kiefel, Milton J. , Houston, Todd A.
- Resource Type: journal article
- Date: 2022
Warburg effect targeting Co(III) cytotoxin chaperone complexes
- Creator: Glenister, Alexandra , Chen, Catherine K. J. , Paterson, David J. , Renfrew, Anna K. , Simone, Michela I. , Hambley, Trevor W.
- Resource Type: journal article
- Date: 2021
Crystal structure of 6-azido-6-deoxy-1,2-O-isopropylidene-a-D-glucofuranose
- Creator: Wood, Adam , Bernhardt, Paul V. , van Altena, Ian , Simone, Michela I.
- Resource Type: journal article
- Date: 2020
Developing new inexpensive room-temperature ionic liquids with high thermal stability and a greener synthetic profile
- Creator: Ghorbani, Mahdi , Simone, Michela I.
- Resource Type: journal article
- Date: 2020
Structural characterisation of new ionic liquids via X-ray crystallography
- Creator: Ghorbani, Mahdi , Bernhardt, Paul V. , Simone, Michela I.
- Resource Type: journal article
- Date: 2020
Tin(IV) compounds of tridentate thiosemicarbazone Schiff bases: synthesis, characterization, in-silico analysis and in vitro cytotoxicity
- Creator: Md Yusof, Enis Nadia , Page, Alister J. , Sakoff, Jennette A. , Simone, Michela I. , Veerakumarasivam, Abhi , Tiekink, Edward R. T. , Ravoof, Thahira B. S. A.
- Resource Type: journal article
- Date: 2020
A Warburg effect targeting vector designed to increase the uptake of compounds by cancer cells demonstrates glucose and hypoxia dependent uptake
- Creator: Glenister, Alexandra , Simone, Michela I. , Hambley, Trevor W.
- Resource Type: journal article
- Date: 2019
Facile amidinations of 2-aminophenylboronic acid promoted by boronate ester formation
- Creator: Pappin, Brighid B. , Garget, Taylor A. , Healy, Peter C. , Simone, Michela I. , Kiefel, Milton J. , Houston, Todd A.
- Resource Type: journal article
- Date: 2019
o-Vanillin derived schiff bases and their organotin(IV) compounds: synthesis, structural characterisation, in-silico studies and cytotoxicity
- Creator: Nadia Md Yusof, Enis , Latif, Muhammad A. M. , Tahir, Mohamed I. M. , Sakoff, Jennette A. , Simone, Michela I. , Page, Alister J. , Veerakumarasivam, Abhi , Tiekink, Edward R. T. , Ravoof, Thahira B. S. A.
- Resource Type: journal article
- Date: 2019
Back to (non-)basics: an update on neutral and charge-balanced glycosidase inhibitors
- Creator: Simone, Michela I. , Mares, Laura J. , Eveleens, Clothilde A. , McCluskey, Adam , Pappin, Brighid B. , Kiefel, Milton J. , Houston, Todd A.
- Resource Type: journal article
- Date: 2018
Biological activities of 3,4,5-trihydroxypiperidines and their N- and O-derivatives
- Creator: Prichard, Kate , Campkin, David , O'Brien, Nicholas , Kato, Atsushi , Fleet, George W. J. , Simone, Michela I.
- Resource Type: journal article
- Date: 2018
Synthesis, characterisation and structure determination of 3-[(1Z)-{2-[bis({[(2-methylphenyl)methyl]sulfanyl})methylidene]hydrazin-1-ylidene}methyl]benzene-1,2-diol
- Creator: Md Yusof, Enis Nadia , Tiekink, Edward R. T. , Jotani, Mukesh M. , Simone, Michela I. , Page, Alister J. , Begum, Thahira B. S. A.
- Resource Type: journal article
- Date: 2018
Synthetic pathways to 3,4,5-trihydroxypiperidines from the chiral pool
- Creator: Wood, Adam , Prichard, Kate L. , Clarke, Zane , Houston, Todd A. , Fleet, George W. J. , Simone, Michela I.
- Resource Type: journal article
- Date: 2018
Synthetic Routes to 3,4,5-Trihydroxypiperidines via Stereoselective and Biocatalysed Protocols, and Strategies to N- and O-Derivatisation
- Creator: Prichard, Kate L. , O'Brien, Nicholas , Ghorbani, Mahdi , Wood, Adam , Barnes, Evan , Kato, Atsushi , Houston, Todd A. , Simone, Michela I.
- Resource Type: journal article
- Date: 2018
The crystal structures of 3-O-benzyl-1,2-O-isopropylidene-5-O-methanesulfonyl-6-O-triphenylmethyl-α-D-glucofuranose and its azidedisplacement product
- Creator: Clarke, Zane , Barnes, Evan , Prichard, Kate L. , Mares, Laura J. , Clegg, Jack K. , McCluskey, Adam , Houston, Todd A. , Simone, Michela I.
- Resource Type: journal article
- Date: 2018
Crystallization-induced amide bond formation creates a boron-centered spirocyclic system
- Creator: Pappin, Brighid B. , Levonis, Stephan M. , Healy, Peter C. , Kiefel, Milton J. , Simone, Michela I. , Houston, Todd A.
- Resource Type: journal article
- Date: 2017
Improved fluorescence assays to measure the defects associated with F508del-CFTR allow identification of new active compounds
- Creator: Langron, Emily , Simone, Michela I. , Delalande, Clémence M. S. , Raymond, Jean-Louis , Selwood, David L. , Vergani, Paola
- Resource Type: journal article
- Date: 2017
Synchrotron based NEXAFS study on nitrogen doped hydrothermalcarbon: insights into surface functionalities and formation mechanisms
- Creator: Latham, Kenneth G. , Simone, Michela I. , Dose, Wesley M. , Allen, Jessica A. , Donne, Scott W.
- Resource Type: journal article
- Date: 2017
Selective inhibition of the mitochondrial permeability transition pore protects against neurodegeneration in experimental multiple sclerosis
- Creator: Warne, Justin , Pryce, Gareth , Chan, A. W. Edith , Towers, Greg J. , Coker, Alun R. , Duchen, Michael R. , Szabadkai, Gyorgy , Baker, David , Selwood, David L. , Hill, Julia M. , Shi, Xiao , Lennerås, Felicia , Puentes, Fabiola , Kip, Maarten , Hilditch, Laura , Walker, Paul , Simone, Michela I.
- Resource Type: journal article
- Date: 2016