Endoplasmic reticulum stress enhances the expression of TLR3-induced TSLP by airway epithelium
- Creator: Pathinayake, Prabuddha S. , Hsu, Alan C.-Y. , Nichol, Kristy S. , Horvat, Jay C. , Hansbro, Philip M. , Wark, Peter A. B.
- Resource Type: journal article
- Date: 2024
Airway inflammatory changes in the lungs of patients with asthma-COPD overlap (ACO): a bronchoscopy endobronchial biopsy study
- Creator: Dey, Surajit , Lu, Wenying , Wark, Peter A. B. , Eapen, Mathew Suji , Sohal, Sukhwinder Singh , Haug, Greg , Chia, Collin , Larby, Josie , Weber, Heinrich C. , Gaikwad, Archana Vijay , Bhattarai, Prem , Shahzad, Affan Mahmood , Pathinayake, Prabuddha S.
- Resource Type: journal article
- Date: 2023
Type 2 Immunity and Its Impact on COVID-19 Infection in the Airways
- Creator: Pathinayake, Prabuddha S. , Awatade, Nikhil T. , Wark, Peter A. B.
- Resource Type: journal article
- Date: 2023
Differential airway remodeling changes were observed in patients with asthma COPD overlap compared to patients with asthma and COPD alone
- Creator: Dey, Surajit , Lu, Wenying , Bhattarai, Prem , Pathinayake, Prabuddha S. , Wark, Peter A. B. , Eapen, Mathew Suji , Sohal, Sukhwinder Singh , Weber, Heinrich C. , Young, Sally , Larby, Josie , Chia, Collin , Haug, Greg , Brake, Samuel James , Myers, Stephen , Gaikwad, Archana Vijay
- Resource Type: journal article
- Date: 2022
The establishment of COPD organoids to study host-pathogen interaction reveals enhanced viral fitness of SARS-CoV-2 in bronchi
- Creator: Chan, Louisa L. Y. , Anderson, Danielle E. , Lee, Ken Cheah Hooi , Nichol, Kristy , Pathinayake, Prabuddha S. , Chan, Yik Lung , Yeo, Tsin Wen , Oliver, Brian G. , Wark, Peter A. B. , Liu, Linbo , Tan, Nguan S. , Wang, Lin -Fa , Cheng, Hong Sheng , Chotirmall, Sanjay H. , Ivan, Fransiskus X. , Chen, Si , Kang, Adrian E. Z. , Foo, Randy , Gamage, Akshamal M. , Tiew, Pei Yee , Koh, Mariko Siyue
- Resource Type: journal article
- Date: 2022
A senescence bystander effect in human lung fibroblasts
- Creator: Waters, David W. , Schuliga, Michael , Mutsaers, Steven E. , Grainge, Christopher L. , Knight, Darryl A. , Pathinayake, Prabuddha S. , Wei, Lan , Tan, Hui-Ying , Blokland, Kaj E. C. , Jaffar, Jade , Westall, Glen P. , Burgess, Janette K. , Prele, Cecilia M.
- Resource Type: journal article
- Date: 2021
ACE2 expression is elevated in airway epithelial cells from older and male healthy individuals but reduced in asthma
- Creator: Wark, Peter A. B. , Pathinayake, Prabuddha S. , Eapen, Mathew S. , Oldmeadow, Christopher , Bartlett, Nathan , Reid, Andrew , Veerati, Punnam , Hsu, Alan C.-Y. , Looi, Kevin , Iosifidis, Thomas , Stick, Stephen M. , Hansbro, Philip M. , Kaiko, Gerard , Kicic, Anthony , Nichol, Kristy , Ali, Ayesha , Chen, Ling , Sutanto, Erika N. , Garratt, Luke W. , Sohal, Sukhwinder S. , Lu, Wenying
- Resource Type: journal article
- Date: 2021
Endoplasmic reticulum-unfolded protein response signalling is altered in severe eosinophilic and neutrophilic asthma
- Creator: Pathinayake, Prabuddha S. , Waters, David W. , Gibson, Peter G. , Hansbro, Philip M. , Wark, Peter A. B. , Nichol, Kristy S. , Brown, Alexandra C. , Reid, Andrew T. , Hsu, Alan Chen-Yu , Horvat, Jay C. , Wood, Lisa G. , Baines, Katherine J. , Simpson, Jodie L.
- Resource Type: journal article
- Date: 2021
The complex interplay between endoplasmic reticulum stress and the NLRP3 inflammasome: a potential therapeutic target for inflammatory disorders
- Creator: Chong, Wai Chin , Shastri, Madhur D. , Peterson, Gregory M. , Patel, Rahul P. , Pathinayake, Prabuddha S. , Dua, Kamal , Hansbro, Nicole G. , Hsu, Alan C. , Wark, Peter A. , Shukla, Shakti Dhar , Johansen, Matt D. , Schroder, Kate , Hansbro, Philip M.
- Resource Type: journal article
- Date: 2021
Crucial role for lung iron level and regulation in the pathogenesis and severity of asthma
- Creator: Ali, Md Khadem , Kim, Richard Y. , Donovan, Chantal , Pathinayake, Prabuddha S. , Carroll, Olivia R. , Trinder, Debbie , Tay, Hock L. , Badi, Yusef E. , Kermani, Nazanin Z. , Guo, Yi-Ke , Aryal, Ritambhara , Mumby, Sharon , Brown, Alexandra C. , Pavlidis, Stelios , Adcock, IM , Weaver, Jessica , Xenaki, D , Oliver, BG , Holliday, Elizabeth G. , Foster, Peter S. , Wark, Peter A. , Johnstone, DM , Milward, EA , Mayall, Jemma R. , Hansbro, Philip M. , Horvat, Jay C. , Karim, Rafia , Pinkerton, James W. , Liu, Gang , Martin, Kristy L. , Starkey, Malcolm R. , Pillar, Amber L.
- Resource Type: journal article
- Date: 2020
Antiviral immunity is impaired in COPD patients with frequent exacerbations
- Creator: Singanayagam, Aran , Bartlett, NW , Mallia, P , Loo, Su-Ling , Reid, Andrew , Footitt, Joseph , Wark, Peter A. B. , Grainge, Christopher L. , Johnston, Sebastian L. , Calderazzo, Maria , Finney, Lydia J. , Torralbo, Maria-Belen Trujillo , Bakhsoliani, Eteri , Girkin, Jason , Veerati, Punnam , Pathinayake, Prabuddha S. , Nichol, Kristy S.
- Resource Type: journal article
- Date: 2019
STAT3 regulates the onset of oxidant-induced senescence in lung fibroblasts
- Creator: Waters, David W. , Blokland, Kaj E. C. , Pathinayake, Prabuddha S. , Wei, Lan , Schuliga, Michael , Jaffar, Jade , Westall, Glen P. , Hansbro, Philip M. , Prele, Cecilia M. , Mutsaers, Steven E. , Bartlett, Nathan W. , Burgess, Janette K. , Grainge, Christopher L. , Knight, Darryl A.
- Resource Type: journal article
- Date: 2019
Corticosteroid suppression of antiviral immunity increases bacterial loads and mucus production in COPD exacerbations
- Creator: Singanayagam, Aran , Glanville, Nicholas , Zhu, Jie , Trujillo-Torralbo, Maria-Belen , Calderazzo, Maria Adelaide , Grainge, Chris , Loo, Su-Ling , Veerati, Punnam Chander , Pathinayake, Prabuddha S. , Nichol, Kristy S. , Reid, Andrew T. , James, Phillip L. , Girkin, Jason L. , Solari, Roberto , Wark, Peter A. B. , Knight, Darryl A. , Moffatt, Miriam F. , Cookson, William O. , Edwards, Michael R. , Mallia, Patrick , Bartlett, Nathan W. , Johnston, Sebastian L. , Ching, Yee Man , Marcellini, Andrea , Porter, James D. , Toussaint, Marie , Walton, Ross P. , Finney, Lydia J. , Aniscenko, Julia
- Resource Type: journal article
- Date: 2018
Fibroblast senescence in the pathology of idiopathic pulmonary fibrosis
- Creator: Waters, David W. , Blokland, Kaj E. C. , Pathinayake, Prabuddha S. , Burgess, Janette K. , Mutsaers, Steven E. , Prele, Cecilia M. , Schuliga, Michael , Grainge, Christopher L. , Knight, Darryl A.
- Resource Type: journal article
- Date: 2018
Inactivated enterovirus 71 with poly-y-glutamic acid/Chitosan nano particles (PC NPs) induces high cellular and humoral immune responses in BALB/c mice
- Creator: Pathinayake, Prabuddha S. , Gayan Chathuranga, W. A. , Lee, Hyan Cheol , Chowdhury, Mohammed Y. E. , Sung, Moon-Hee , Lee, Jong-Soo , Kim, Chul-Joong
- Resource Type: journal article
- Date: 2018
Understanding the Unfolded Protein Response in the Pathogenesis of Asthma
- Creator: Pathinayake, Prabuddha S. , Hsu, Alan C.-Y. , Waters, David W. , Hansbro, Philip M. , Wood, Lisa G. , Wark, Peter A. B.
- Resource Type: journal article
- Date: 2018
Innate immunity and immune evasion by Enterovirus 71
- Creator: Pathinayake, Prabuddha S. , Hsu, Alan C.-Y. , Wark, Peter A. B.
- Resource Type: journal article
- Date: 2015