Genomic and phenotypic insights from an atlas of genetic effects on DNA methylation
- Creator: Min, Josine L. , Hemani, Gibran , Bretherick, Andrew D. , Pennell, Craig E. , Richardson, Tom G. , Klughammer, Johanna , Iotchkova, Valentina , Sharp, Gemma , Al Khleifat, Ahmad , Shatunov, Aleksey , Iacoangeli, Alfredo , McArdle, Wendy L. , Ho, Karen M. , Hannon, Ellis , Kumar, Ashish , Söderhäll, C , Soriano-Tárraga, C , Giralt-Steinhauer, E , Kazmi, N , Mason, D , McRae, AF , Corcoran, DL , Sugden, K , Kasela, S , Dekkers, Koen F. , Cardona, A , Day, FR , Cugliari, G , Viberti, C , Guarrera, S , Lerro, M , Gupta, R , Bollepalli, S , Mandaviya, P , Zeng, Y , Castillo-Fernandez, Juan , Clarke, TK , Walker, RM , Schmoll, V , Czamara, D , Ruiz-Arenas, C , Rezwan, FI , Marioni, RE , Lin, T , Awaloff, Y , Germain, M , Luijk, Rene , Aïssi, D , Zwamborn, R , van Eijk, K , Dekker, A , van Dongen, J , Hottenga, JJ , Willemsen, G , Xu, CJ , Barturen, G , Català-Moll, F , Carnero-Montoro, Elena , Kerick, M , Wang, Carol , Melton, P , Elliott, HR , Shin, J , Bernard, M , Yet, I , Smart, M , Gorrie-Stone, T , Shaw, C , Lawson, Daniel J. , Al Chalabi, A , Ring, SM , Pershagen, G , Melén, E , Jiménez-Conde, J , Roquer, J , Lawlor, DA , Wright, J , Martin, NG , Montgomery, GW , Burrows, Kimberley , Moffitt, TE , Poulton, R , Esko, T , Milani, L , Metspalu, A , Perry, JRB , Ong, KK , Wareham, NJ , Matullo, G , Sacerdote, C , Suderman, Matthew , Panico, S , Caspi, A , Arseneault, L , Gagnon, F , Ollikainen, M , Kaprio, J , Felix, JF , Rivadeneira, F , Tiemeier, H , van IJzendoorn, MH
- Resource Type: journal article
- Date: 2021
Mendelian randomization analysis does not support causal associations of birth weight with hypertension risk and blood pressure in adulthood
- Creator: Zheng, Yan , Huang, Tao , Tai, E-Shyong , Koh, Woon-Puay , Dorajoo, Rajkumar , Saw, Seang-Mei , Sabanayagam, Charumathi , Wong, Tien Yin , Gupta, Preeti , Rossing, Peter , Ahluwalia, Tarunveer S. , Vinding, Rebecca K. , Wang, Tiange , Bisgaard, H , Bønnelykke, K , Wang, Y , Graff, M , Voortman, T , van Rooij, FJA , Hofman, A , van Heemst, D , Noordam, R , Estampador, AC , Mei, Zhendong , Varga, TV , Enzenbach, C , Scholz, M , Thiery, J , Burkhardt, R , Orho-Melander, M , Schulz, CA , Ericson, U , Sonestedt, E , Kubo, M , Sun, Zhonghan , Akiyama, M , Zhou, A , Kilpeläinen, TO , Hansen, T , Kleber, ME , Delgado, G , McCarthy, M , Lemaitre, RN , Felix, JF , Jaddoe, VWV , Zhang, Tao , Wu, Y , Mohlke, KL , Lehtimäki, T , Wang, Carol A. , Pennell, CE , Schunkert, H , Kessler, T , Zeng, L , Willenborg, C , Peters, A , Ellervik, Christina , Lieb, W , Grote, V , Rzehak, P , Koletzko, B , Erdmann, J , Munz, M , Wu, T , He, M , Yu, C , Lecoeur, C , Chai, Jin-Fang , Froguel, P , Corella, D , Moreno, LA , Lai, CQ , Pitkänen, N , Boreham, CA , Ridker, PM , Rosendaal, FR , de Mutsert, R , Power, C , Sim, Xueling , Paternoster, L , Sørensen, TIA , Tjønneland, A , Overvad, K , Djousse, L , Rivadeneira, F , Lee, NR , Raitakari, OT , Kähönen, M , Viikari, J , van Dam, Rob M. , Langhendries, JP , Escribano, J , Verduci, E , Dedoussis, G , König, I , Balkau, B , Coltell, O , Dallongeville, J , Meirhaeghe, A , Amouyel, P
- Resource Type: journal article
- Date: 2020
Novel loci for childhood body mass index and shared heritability with adult cardiometabolic traits
- Creator: Vogelezang, Suzanne , Vinding, RK , Vogel, M , Zeggini, E , Sebert, S , Lind, MV , Brown, CD , Santa-Marina, L , Reischl, E , Frithioff-Bojsoe, C , Meyre, D , Wheeler, E , Ong, K , Nohr, EA , Vrijkotte, TGM , Koppelman, GH , Plomin, R , Njolstad, PR , Dedoussis, GD , Froguel, P , Sorensen, TIA , Jacobsson, B , Freathy, RM , Zemel, BS , Raitakari, O , Vrijheid, M , Feenstra, B , Lyytikainen, L-P , Snieder, H , Kirsten, H , Holt, PG , Heinrich, J , Widen, E , Sunyer, J , Boomsma, DI , Jarvelin, M-R , Koerner, A , Davey Smith, G , Holm, J-C , Atalay, M , Murray, C , Bisgaard, H , McCarthy, MI , Jaddoe, VWV , Grant, SFA , Felix, JF , Bradfield, Jonathon P. , Heiskala, Anni , Horikoshi, Momoko , Fedko, Iryna O. , Vilor-Tejedor, Natalia , Cousminer, Diana L. , Standl, Marie , Wang, Carol A. , Viikari, Jorma , Geller, Frank , Iniguez, Carmen , Ahluwalia, Tarunveer S. , Pitkanen, N , Chesi, A , Bacelis, J , Yengo, L , Torrent, M , Ntalla, I , Helgeland, O , Selzam, S , Vonk, JM , Zafarmand, MH , Curtin, John A. , Heude, B , Farooqi, IS , Alyass, A , Beaumont, RN , Have, CT , Rzehak, P , Bilbao, JR , Schnurr, TM , Barroso, I , Bonnelykke, K , Lakka, Timo A. , Beilin, LJ , Carstensen, L , Charles, M-A , Chawes, B , Clement, K , Closa-Monasterolo, R , Custovic, A , Eriksson, JG , Escribano, J , Groen-Blokhuis, M , Grarup, Niels , Grote, V , Gruszfeld, D , Hakonarson, H , Hansen, T , Hattersley, AT , Hollensted, M , Hottenga, J-J , Hypponen, E , Johansson, S , Joro, R , Scholz, Markus , Kahonen, M , Karhunen, V , Kiess, W , Knight, BA , Koletzko, B , Kuehnapfel, A , Landgraf, K , Langhendries, J-P , Lehtimaki, T , Leinonen, JT , van der Most, Peter J. , Li, A , Lindi, V , Lowry, E , Bustamante, M , Medina-Gomez, C , Melbye, M , Michaelsen, KF , Morgen, CS , Mori, TA , Nielsen, TRH , Monnereau, Claire , Niinikoski, H , Oldehinkel, AJ , Pahkala, K , Panoutsopoulou, K , Pedersen, O , Pennell, CE , Power, C , Reijneveld, SA , Rivadeneira, F , Simpson, A , Stergiakouli, Evie , Sly, PD , Stokholm, J , Teo, KK , Thiering, E , Timpson, NJ , Uitterlinden, AG , van Beijsterveldt, CEM , van Schaik, BDC , Vaudel, M , Verduci, E
- Resource Type: journal article
- Date: 2020
Association of Birth Weight With Type 2 Diabetes and Glycemic Traits: A Mendelian Randomization Study
- Creator: Huang, Tao , Wang, Tiange , Voortman, Trudy , Sabanayagam, C , Tai, E-S , Mohlke, KL , Mackey, DA , Gruszfeld, D , Deloukas, P , Tucker, KL , Fumeron, F , Bonnelykke, K , Rossing, P , Noordam, Raymond , Estruch, R , Ordovas, JM , Arnett, DK , Meirhaeghe, A , Amouyel, P , Cheng, C-Y , Sim, X , Teo, YY , van Dam, RM , Koh, W-P , Frazier-Wood, Alexis , Orho-Melander, M , Loeffler, M , Kubo, M , Thiery, J , Mook-Kanamori, DO , Mozaffarian, D , Psaty, BM , Franco, OH , Wu, T , North, KE , Scholz, Markus , Smith, GD , Chavarro, JE , Chasman, DI , Qi, L , Sonestedt, Emily , Akiyama, Masato , Dorajoo, Rajkumar , Zhou, Ang , Kilpeläinen, Tuomas O. , Kleber, Marcus E. , Zheng, Yan , Wang, Carol A. , Godfrey, KM , Lemaitre, R , Felix, JF , Shi, Y , Gupta, P , Khor, C-C , Lehtimaki, T , Wang, CA , Tiesler, CMT , Ellervik, Christina , Thiering, E , Standl, M , Rzehak, P , Marouli, E , He, M , Lecoeur, C , Corella, D , Lai, C-Q , Moreno, LA , Pitkanen, N , Li, Xiang , Boreham, CA , Zhang, T , Saw, SM , Ridker, PM , Graff, M , Van Rooij, FJA , Uitterlinden, AG , Hofman, A , van Heemst, D , Rosendaal, FR , Gao, Meng , de Mutsert, R , Burkhardt, R , Schulz, C-A , Ericson, U , Kamatani, Y , Yuan, J-M , Power, C , Hansen, T , Sorensen, TIA , Tjonneland, A , Fang, Zhe , Overvad, K , Delgado, G , Cooper, C , Djousse, L , Rivadeneira, F , Jameson, K , Zhao, W , Liu, J , Lee, NR , Raitakari, O , Chai, Jin-Fang , Kahonen, M , Viikari, J , Grote, V , Langhendries, J-P , Koletzko, B , Escribano, J , Verduci, E , Dedoussis, G , Yu, C , Tham, YC , Ahluwalia, Tarun veer S. , Lim, B , Lim, SH , Froguel, P , Balkau, B , Fink, NR , Vinding, RK , Sevelsted, A , Bisgaard, H , Coltell, O , Dallongeville, J , Wang, Yujie , Gottrand, F , Pahkala, K , Niinikoski, H , Hypponen, E , Pedersen, O , Marz, W , Inskip, H , Jaddoe, VV , Dennison, E , YinWong, T
- Resource Type: journal article
- Date: 2019
Associations of autozygosity with a broad range of human phenotypes
- Creator: Clark, David W. , Cocca, M , Collins, FS , Concas, MP , Corley, J , Cugliari, G , Van Dam, RM , Damulina, A , Daneshpour, MS , Day, FR , Delgado, GE , Dhana, K , Doney, ASF , Doerr, M , Doumatey, AP , Dzimiri, N , Ebenesersdottir, SS , Elliott, J , Elliott, P , Ewert, R , Felix, JF , Fischer, K , Freedman, BI , Girotto, G , Goel, A , Gogele, M , Goodarzi, MO , Graff, M , Granot-Hershkovitz, E , Grodstein, F , Guarrera, S , Gudbjartsson, DF , Guity, K , Gunnarsson, B , Guo, Y , Hagenaars, SP , Haiman, CA , Halevy, A , Harris, TB , Hedayati, M , van Heel, DA , Hirata, M , Hofer, I , Hsiung, CA , Huang, J , Hung, Y-J , Ikram, MA , Jagadeesan, A , Jousilahti, P , Kamatani, Y , Kanai, M , Kerrison, ND , Kessler, T , Khaw, K-T , Khor, CC , de Kleijn, DPV , Koh, W-P , Kolcic, I , Kraft, P , Kramer, BK , Kutalik, Z , Kuusisto, J , Langenberg, C , Launer, LJ , Lawlor, DA , Lee, I-T , Lee, W-J , Lerch, MM , Li, L , Liu, J , Loh, M , London, SJ , Loomis, S , Lu, Y , Luan, J , Magi, R , Manichaikul, AW , Manunta, P , Masson, G , Matoba, N , Mei, XW , Meisinger, C , Meitinger, T , Mezzavilla, M , Milani, L , Millwood, IY , Momozawa, Y , Moore, A , Morange, P-E , Moreno-Macias, H , Mori, TA , Morrison, AC , Muka, T , Murakami, Y , Murray, AD , de Mutsert, R , Mychaleckyj, JC , Nalls, MA , Nauck, M , Neville, MJ , Nolte, IM , Ong, KK , Orozco, L , Padmanabhan, S , Palsson, G , Pankow, JS , Pattaro, C , Pattie, A , Polasek, O , Poulter, N , Pramstaller, PP , Quintana-Murci, L , Raikkonen, K , Ralhan, S , Rao, DC , van Rheenen, W , Rich, SS , Ridker, PM , Rietveld, CA , Robino, A , van Rooij, FJA , Ruggiero, D , Saba, Y , Sabanayagam, C , Sabater-Lleal, M , Felicita Sala, C , Salomaa, V , Sandow, K , Schmidt, H , Scott, LJ , Scott, WR , Sedaghati-Khayat, B , Sennblad, B , van Setten, J , Sever, PJ , Sheu, WH-H , Shi, Y , Shrestha, S , Shukla, SR , Sigurdsson, JK , Sikka, TT , Singh, JR , Smith, BH , Stancakova, A , Stanton, A , Starr, JM , Stefansdottir, L , Straker, L , Sulem, P , Sveinbjornsson, G , Swertz, MA , Taylor, AM , Taylor, KD , Terzikhan, N , Tham, Y-C , Thorleifsson, G , Thorsteinsdottir, U , Tillander, A , Tracy, RP , Tusie-Luna, T , Tzoulaki, I , Vaccargiu, S , Vangipurapu, J , Veldink, JH , Vitart, V , Volker, U , Vuoksimaa, E , Wakil, SM , Waldenberger, M , Wander, GS , Wang, YX , Wareham, NJ , Wild, S , Yajnik, CS , Yuan, J-M , Zeng, L , Zhang, L , Zhou, J , Amin, N , Asselbergs, FW , Bakker, SJL , Becker, DM , Lehne, B , Bennett, DA , van den Berg, LH , Berndt, SI , Bharadwaj, D , Bielak, LF , Bochud, M , Boehnke, M , Bouchard, C , Bradfield, JP , Brody, JA , Campbell, A , Carmi, S , Caulfield, MJ , Cesarini, D , Chambers, JC , Chandak, GR , Cheng, C-Y , Ciullo, M , Cornelis, M , Cusi, D , Smith, GD , Deary, IJ , Dorajoo, R , van Duijn, CM , Ellinghaus, D , Erdmann, J , Eriksson, JG , Evangelou, E , Evans, MK , Faul, JD , Feenstra, B , Feitosa, M , Foisy, S , Franke, A , Friedlander, Y , Gasparini, P , Gieger, C , Gonzalez, C , Goyette, P , Grant, SFA , Griffiths, LR , Groop, L , Gudnason, V , Gyllensten, U , Hakonarson, H , Hamsten, A , van der Harst, P , Heng, C-K , Hicks, AA , Hochner, H , Huikuri, H , Hunt, SC , Jaddoe, VWV , De Jager, PL , Johannesson, M , Johansson, A , Jonas, JB , Jukema, JW , Junttila, J , Kaprio, J , Kardia, SLR , Karpe, F , Kumari, M , Laakso, M , van der Laan, SW , Lahti, J , Laudes, M , Lea, RA , Lieb, W , Lumley, T , Martin, NG , Marz, W , Matullo, G , McCarthy, MI , Medland, SE , Merriman, TR , Metspalu, A , Meyer, BF , Mohlke, KL , Montgomery, GW , Mook-Kanamori, D , Munroe, PB , North, KE , Nyholt, DR , O'connell, JR , Ober, C , Oldehinkel, AJ , Palmas, W , Palmer, C , Pasterkamp, GG , Patin, E , Pennell, CE , Perusse, L , Peyser, PA , Pirastu, M , Polderman, TJC , Porteous, DJ , Posthuma, D , Psaty, BM , Rioux, JD , Rivadeneira, F , Rotimi, C , Rotter, JI , Rudan, I , Den Ruijter, HM , Sanghera, DK , Sattar, N , Schmidt, R , Schulze, MB , Schunkert, H , Scott, RA , Shuldiner, AR , Sim, X , Small, N , Smith, JA , Sotoodehnia, N , Tai, E-S , Teumer, A , Timpson, NJ , Toniolo, D , Tregouet, D-A , Tuomi, T , Vollenweider, P , Wang, CA , Weir, DR , Whitfield, JB , Wijmenga, C , Wong, T-Y , Wright, J , Yang, J , Yu, L , Zemel, BS , Zonderman, AB , Perola, M , Magnusson, PKE , Uitterlinden, AG , Kooner, JS , Chasman, DI , Loos, RJF , Franceschini, N , Franke, L , Haley, CS , Hayward, C , Walters, RG , Perry, JRB , Esko, T , Helgason, A , Stefansson, K , Joshi, PK , Kubo, M , Wilson, JF , Okada, Yukinori , Deelen, Patrick , Wang, Carol A. , Pennell, Craig E. , Orozco, Lorena , Rohde, Rebecca , Schurmann, Claudia , Guo, Xiuqing , Giulianini, Franco , Zhang, Weihua , Medina-Gomez, Carolina , Karlsson, Robert , Bao, Yanchun , Bartz, Traci M. , Moore, Kristjan H. S. , Baumbach, Clemens , Biino, G , Bixley, MJ , Brumat, M , Chai, J-F , Corre, T , Cousminer, DL , Dekker, AM , Eccles, DA , Van Eijk, KR , Mason, Dan , Fuchsberger, C , Gao, H , Germain, M , Gordon, SD , de Haan, HG , Harris, SE , Hofer, E , Huerta-Chagoya, A , Igartua, C , Jansen, IE , Pirastu, Nicola , Jia, Y , Kacprowski, T , Karlsson, T , Kleber, ME , Li, SA , Li-Gao, R , Mahajan, A , Matsuda, K , Meidtner, K , Meng, W , Gandin, Ilaria , Montasser, ME , van der Most, PJ , Munz, M , Nutile, T , Palviainen, T , Prasad, G , Prasad, RB , Priyanka, TDS , Rizzi, F , Salvi, E , Mattsson, Hannele , Sapkota, BR , Shriner, D , Skotte, L , Smart, MC , Smith, AV , van der Spek, A , Spracklen, CN , Strawbridge, RJ , Tajuddin, SM , Trompet, S , Barnes, Catriona L. K. , Turman, C , Verweij, N , Viberti, C , Wang, L , Warren, HR , Wootton, RE , Yanek, LR , Yao, J , Yousri, NA , Zhao, W , Lin, Kuang , Adeyemo, AA , Afaq, S , Alberto Aguilar-Salinas, C , Akiyama, M , Albert, ML , Allison, MA , Alver, M , Aung, T , Azizi, F , Bentley, AR , Zhao, Jing Hua , Boeing, H , Boerwinkle, E , Borja, JB , de Borst, GJ , Bottinger, EP , Broer, L , Campbell, H , Chanock, S , Chee, M-L , Chen, G
- Resource Type: journal article
- Date: 2019
Variants in the fetal genome near pro-inflammatory cytokine genes on 2q13 associate with gestational duration
- Creator: Liu, Xueping , Helenius, Dorte , Skotte, Line , Beaumont, Robin N. , Wielscher, Matthias , Geller, Frank , Juodakis, Julius , Mahajan, Anubha , Bradfield, Jonathan P. , Lin, Frederick T. J. , Vogelezang, Suzanne , Bustamante, Mariona , Ahluwalia, Tarunveer S. , Pitkänen, Niina , Wang, Carol A. , Bacelis, Jonas , Borges, Maria C. , Zhang, Ge , Bedell, Bruce A. , Rossi, Robert M. , Pennell, Craig E. , Skogstrand, Kristin , Peng, S , Thompson, WK , Appadurai, V , Lawlor, DA , Kalliala, I , Power, C , McCarthy, MI , Boyd, HA , Marazita, ML , Hakonarson, H , Hayes, MG , Scholtens, DM , Rivadeneira, F , Jaddoe, VWV , Vinding, RK , Bisgaard, H , Knight, BA , Pahkala, K , Raitakari, O , Helgeland, Ø , Johansson, S , Njølstad, PR , Fadista, J , Schork, AJ , Nudel, R , Miller, DE , Chen, X , Weirauch, MT , Mortensen, PB , Børglum, AD , Nordentoft, M , Mors, O , Hao, K , Ryckman, KK , Hougaard, DM , Kottyan, LC , Lyytikainen, LP , Bønnelykke, K , Vrijheid, M , Felix, JF , Lowe, WL , Grant, SFA , Hyppönen, E , Jacobsson, B , Jarvelin, MR , Muglia, LJ , Murray, JC , Freathy, RM , Werge, TM , Melbye, M , Buil, A , Feenstra, B
- Resource Type: journal article
- Date: 2019