Association of MTHFR C677T genotype with ischemic stroke is confined to cerebral small vessel disease subtype
- Creator: Rutten-Jacobs, Loes C. A. , Traylor, Matthew , Levi, Christopher , Rost, Natalia S. , Rosand, Jonathan , Hassan, Ahamad , Bevan, Steve , Markus, Hugh S. , Adib-Samii, Ppneh , Thijs, Vincent , Sudlow, Cathie , Rothwell, Peter M. , Boncoraglio, Giorgio , Dichgans, Martin , Meschia, James , Maguire, Jane
- Resource Type: journal article
- Date: 2016
Genetic associations with white matter hyperintensities confer risk of lacunar stroke
- Creator: Traylor, Matthew , Rutten-Jacobs, Loes C. A. , Dichgans, Martin , Markus, Hugh S. , Thijs, Vincent , Holliday, Elizabeth G. , Levi, Chris , Bevan, Steve , Malik, Rainer , Boncoraglio, Giorgio , Sudlow, Cathie , Rothwell, Peter M.
- Resource Type: journal article
- Date: 2016
Loci associated with ischaemic stroke and its subtypes (SiGN): a genome-wide association study
- Creator: Rosand, Jonathan , Mitchell, Braxton D. , Thijs, Vincent , Woo, Daniel , Worrall, Bradford B. , Arnett, Donna K. , Benavente, Oscar , Cole, John W. , Dichgans, Martin , Grewal, Raji P. , Jern, Christina , Conde, Jordi Jiménez , Ay, Hakan , Johnson, Julie A. , Lee, Jin-Moo , Levi, Christopher , Markus, Hugh S. , Melander, Olle , Rexrode, Kathryn , Rothwell, Peter M. , Rundek, Tatjana , Sacco, Ralph L. , Schmidt, Reinhold , de Bakker, Paul I. W. , Sharma, Pankaj , Slowik, Agnieszka , Wasssertheil-Smoller, Sylvia , Gwinn, Katrina , Kittner, Steven J. , Lindgren, Anne , Meschia, James F. , Pulit, Sarah L. , Sudlow, Cathie L. M.
- Resource Type: journal article
- Date: 2016
Common NOTCH3 variants and cerebral small-vessel disease
- Creator: Rutten-Jacobs, Loes C. A. , Traylor, Matthew , Levi, Christopher , Rost, Natalia S. , Rosand, Jonathan , Hassan, Ahamad , Markus, Hugh S. , Adib-Samii, Poneh , Thijs, Vincent , Sudlow, Cathie , Rothwell, Peter M. , Boncoraglio, Giorgio , Dichgans, Martin , Bevan, Steve , Meschia, James
- Resource Type: journal article
- Date: 2015
Differences in common genetic predisposition to ischemic stroke by age and sex
- Creator: Traylor, Matthew , Rutten-Jacobs, Loes C. A. , Dichgans, Martin , Levi, Chris , Lewis, Cathryn M. , Markus, Hugh S. , Holliday, Elizabeth G. , Malik, Rainer , Sudlow, Cathie , Rothwell, Peter M. , Maguire, Jane M. , Koblar, Simon A. , Bevan, Steve , Boncoraglio, Giorgio
- Resource Type: journal article
- Date: 2015
Genetic architecture of white matter hyperintensities differs in hypertensive and nonhypertensive ischemic stroke
- Creator: Adib-Samii, Poneh , Devan, William , Rothwell, Peter M. , Sudlow, Cathie , Boncoraglio, Giorgio B. , Meschia, James F. , Levi, Chris , Dichgans, Martin , Bevan, Steve , Rosand, Jonathan , Rost, Natalia S. , Markus, Hugh S. , Traylor, Matthew , Lanfranconi, Silvia , Zhang, Cathy R. , Cloonan, Lisa , Falcone, Guido J. , Radmanesh, Farid , Fitzpatrick, Kaitlin , Kanakis, Allison
- Resource Type: journal article
- Date: 2015
No additional prognostic value of genetic information in the prediction of vascular events after cerebral ischemia of arterial origin: The PROMISe study
- Creator: Achterberg, Sefanja , Kappelle, L. Jaap , Mali, W.P.T.M. , Doevendans, P.A. , Farrall, Martin , Holliday, Elizabeth G. , Sudlow, Cathie , Hopewell, Jemma C. , Cheng, Yu-Ching , Fornage, Myriam , Ikram, M. Arfan , Malik, Rainer , De Bakker, Paul I. W. , Bevan, Steve , Thorsteinsdottir, Unnur , DeStefano, Anita L. , Worrall, Bradford B. , Reiner, Alex P. , Mitchell, Braxtin D. , Clarke, Robert , Levi, Christopher , Seshadri, Sudha , Boncoraglio, Giorgio B. , Traylor, Matthew , Sharma, Pankaj , Bis, Joshua C. , Gretarsdottir, Solveig , Psaty, Bruce M. , Rothwell, Peter M. , Rosand, Jonathan , Meschia, James F. , Stefansson, Kari , Dichgans, Martin , Markus, Hugh S. , Algra, Ale , Van Der Graaf, Y. , Grobbee, D.E. , Rutten, G.E.H.M. , Visseren, F.L.J. , Moll, F.L.
- Resource Type: journal article
- Date: 2015
Shared genetic basis for migraine and ischemic stroke: a genome-wide analysis of common variants
- Creator: Malik, Rainer , Freilinger, Tobias , Bis, Joshua C. , Hopewell, Jemma C. , Ferrari, Michel D. , Rannikmae, Kristiina , Wessman, Maija , Kallela, Mikko , Kubisch, Christian , Fornage, Myriam , Meschia, James F. , Lehtimäki, Terho , Winsvold, Bendik S. , Sudlow, Cathie , Clarke, Robert , Chasman, Daniel I. , Mitchell, Braxton D. , Maguire, Jane , Kaprio, Jakko , Farrall, Martin , Raitakari, Olli T. , Kurth, Tobias , Ikram, M. Arfan , Anttila, Verneri , Reiner, Alex P. , Longstreth, W. T. , Rothwell, Peter M. , Strachan, David P. , Sharma, Pankaj , Seshadri, Sudha , Quaye, Lydia , Cherkas, Lynn , Schürks, Markus , Rosand, Jonathan , Vander Heiden, Jason , Ligthart, Lannie , Boncoraglio, Giorgio B. , Davey Smith, George , van Duijn, Cornelia M. , Stefansson, Kari , Worrall, Bradford B. , Nyholt, Dale R. , Markus, Hugh S. , van den Maagdenberg, Arn M. J. M. , Cotsapas, Chris , Traylor, Matthew , Zwart, John A. , Palotie, Aarno , Dichgans, Martin , de Vries, Boukje , Holliday, Elizabeth G. , Terwindt, Gisela M. , Sturm, Jonathan
- Resource Type: journal article
- Date: 2015
A novel MMP12 locus Is associated with large artery atherosclerotic stroke using a genome-wide age-at-onset informed approach
- Creator: Traylor, Matthew , Mäkelä, Kari-Matti , Malik, Rainer , Sudlow, Cathie , Bevan, Steve , Raitoharju, Emma , Oksala, Niku , Thijs, Vincent , Lemmens, Robin , Lindgren, Arne , Slowik, Agnieszka , Kilarski, Laura L. , Maguire, Jane M. , Walters, Matthew , Algra, Ale , Sharma, Pankaj , Attia, John R. , Boncoraglio, Giorgio B. , Rothwell, Peter M. , de Bakker, Paul I. W. , Bis, Joshua C. , Saleheen, Danish , Holliday, ELizabeth G. , Kittner, Steven J. , Mitchell, Braxton D. , Rosand, Jonathan , Meschia, James F. , Levi, Christopher , Dichgans, Martin , Lehtimäki, Terho , Lewis, Cathryn M. , Markus, Hugh S. , Devan, William J. , Nalls, Mike A. , Wiggins, Kerri L. , Zhao, Wei , Cheng, Yu-Ching , Achterberg, Sefanja
- Resource Type: journal article
- Date: 2014
Effect of genetic variants associated with plasma homocysteine levels on stroke risk
- Creator: Cotlarciuc, Iona , Malik, Rainer , Markus, Hugh S. , Rosand, Jonathan , Mitchell, Braxton D. , Kittner, Steven J. , Meschia, James F. , van Meurs, Joyce B. J. , Uitterlinden, Andre G. , Worrall, Bradford B. , Dichgans, Martin , Sharma, Pankaj , Holliday, Elizabeth G. , Ahmadi, Kourosh R. , Paré, Guillaume , Psaty, Bruce M. , Fornage, Myriam , Hasan, Nazeeha , Rinne, Paul E. , Ikram, M. Arfan
- Resource Type: journal article
- Date: 2014
Meta-analysis in more than 17,900 cases of ischemic stroke reveals a novel association at 12q24.12
- Creator: Kilarski, Laura L. , Achterberg, Sefanja , Walters, Matthew , Worrall, Bradford B. , Sale, Michele M. , Algra, Ale , Kappelle, L. Jaap , Wijmenga, Cisca , Norrving, Bo , Sandling, Johanna K. , Röennblom, Lars , Goris, An , Devan, William J. , Franke, Andre , Sudlow, Cathie , Rothwell, Peter M. , Levi, Christopher , Holliday, Elizabeth G. , Fornage, Myriam , Psaty, Bruce , Gretarsdottir, Solveig , Thorsteinsdottir, Unnar , Seshadri, Sudha , Traylor, Matthew , Mitchell, Braxton D. , Kittner, Steven , Clarke, Robert , Hopewell, Jemma C. , Bis, Joshua C. , Boncoraglio, Giorgio B. , Meschia, James , Ikram, M. Arfan , Hansen, Bjorn M. , Montaner, Joan , Malik, Rainer , Thorleifsson, Gudmar , Stefanson, Kari , Rosand, Jonathan , de Bakker, Paul I. W. , Farrall, Martin , Dichgans, Martin , Markus, Hugh S. , Bevan, Steve , Lindgren, Arne , Pare, Guillame , Sharma, Pankaj , Slowik, Agniescka , Thijs, Vincent
- Resource Type: journal article
- Date: 2014
Multilocus genetic risk score associates with ischemic stroke in case-control and prospective cohort studies
- Creator: Malik, Rainer , Bevan, Steve , de Stefano, Anita L. , Fornage, Myriam , Psaty, Bruce M. , Ikram, M. Afran , Launer, Lenore J. , Van Duijn, Cornelia M. , Sharma, Pankaj , Mitchell, Braxton D. , Rosand, Jonathan , Meschia, James F. , Nalls, Michael A. , Levi, Christopher , Rothwell, Peter M. , Sudlow, Cathie , Markus, Hugh S. , Seshadri, Sudha , Dichgans, Martin , MD Wellcome Trust Case Control Consortium 2, , Holliday, Elizabeth G. , Devan, William J. , Cheng, Yu-Ching , Ibrahim-Verbaas, Carla A. , Verhaaren, Benjamin F. J. , Bis, Joshua C. , Joon, Aron Y.
- Resource Type: journal article
- Date: 2014
Pathogenic ischemic stroke phenotypes in the NINDS-Stroke Genetics Network
- Creator: Ay, Hakan , Arsava, Ethem Murat , Giralt-Steinhauer, Eva , Grewal, Raji P. , Gwinn, Katrina , Jern, Christina , Jimenez-Conde, Jordi , Jood, Katarina , Katsnelson, Michael , Kissela, Brett , Kittner, Steven J. , Kleindorfer, Dawn O. , Andsberg, Gunnar , Labovitz, Daniel L. , Lanfranconi, Silvia , Lee, Jin-Moo , Lehm, Manuel , Lemmens, Robin , Levi, Chris , Li, Linxin , Lindgren, Arne , Markus, Hugh S. , McArdle, Patrick F. , Benner, Thomas , Melander, Olle , Norrving, Bo , Peddareddygari, Leema Reddy , Pedersen, Annie , Pera, Joanna , Rannikmaee, Kristiina , Rexrode, Kathyrn M. , Rhodes, David , Rich, Stephen S. , Roquer, Jaume , BrownJr, Robert D. , Rosand, Jonathan , Rothwell, Peter M. , Rundek, Tatjana , Sacco, Ralph L. , Schmidt, Reinhold , Schurks, Markus , Seiler, Stephan , Sharma, Pankaj , Slowik, Agnieszka , Sudlow, Cathie , Chapman, Sherita N. , Thijs, Vincent , Woodfield, Rebecca , Worrall, Bradford B. , Meschia, James F. , Cole, John W. , Delavaran, Hossein , Dichgans, Martin , Engstroem, Gunnar
- Resource Type: journal article
- Date: 2014
Polygenic overlap between kidney function and large artery atherosclerotic stroke
- Creator: Holliday, Elizabeth G. , Traylor, Matthew , Sudlow, Cathie , Rothwell, Peter M. , Coresh, Josef , Hamet, Pavel , Tremblay, Johanne , Turner, Stephen T. , de Andrade, Mariza , Rao, Madhumathi , Schmidt, Reinhold , Crick, Peter A. , Malik, Rainer , Robino, Antonietta , Peralta, Carmen A. , Jukema, J. Wouter , Mitchell, Paul , Rosas, Silvia E. , Wang, Jie Jin , Scott, Rodney J. , Dichgans, Martin , Mitchell, Braxton D. , Kao, W. H. Linda , Bevan, Stephen , Fox, Caroline S. , Levi, Christopher , Attia, John , Markus, Hugh S. , Maguire, Jane , Koblar, Simon A. , Sturm, Jonathan , Hankey, Graeme J. , Oldmeadow, Christopher , McEvoy, Mark
- Resource Type: journal article
- Date: 2014
Shared genetic susceptibility to ischemic stroke and coronary artery disease : a genome-wide analysis of common variants
- Creator: Dichgans, Martin , Malik, Rainer , Ódonnell, Christopher J. , Fornage, Myriam , Thorsteinsdottir, Unnur , Psaty, Bruce M. , Hengstenberg, Christian , Seshadri, Sudha , Erdmann, Jeanette , Bis, Joshua C. , Peters, Annette , Boncoraglio, Giorgio B. , König, Inke R. , März, Winfred , Meschia, James F. , Kathiresan, Sekar , Ikram, M. Arfan , McPherson, Ruth , Stefansson, Kari , Sudlow, Cathie , Reilly, Muredach , Thompson, John R. , Sharma, Pankaj , Rosand, Jonathon , Hopewell, Jemma C. , Chambers, John C. , Watkins, Hugh , Rothwell, Peter M. , Roberts, Robert , Markus, Hugh S. , Samani, Nilesh J. , Farrall, Martin , Schunkert, Heribert , Clarke, Robert , Gretarsdottir, Solveig , Thorleifsson, Gudmar , Mitchell, Branxton D. , Assimes, Themistocles L. , Levi, Christopher
- Resource Type: journal article
- Date: 2014
17q25 Locus is associated with white matter hyperintensity volume in ischemic stroke, but not with lacunar stroke status
- Creator: Adib-Samii, Poneh , Rost, Natalia , Gschwendtner, Andreas , Malik, Rainer , Richie, Alexa , Gamble, Dale , Segal, Helen , Parati, Eugenio A. , Ciusani, Emilio , Holliday, Elizabeth G. , Maguire, Jane , Wardlaw, Joanna , Traylor, Matthew , Worrall, Bradford , Bis, Joshua , Wiggins, Kerri L. , Longstreth, Will , Kittner, Steve J. , Cheng, Yu-Ching , Mosley, Thomas , Falcone, Guido J. , Furie, Karen L. , Leiva-Salinas, Carlos , Devan, William , Lau, Benison C. , Saleem Khan, Muhammed , Australian Stroke Genetics Collaborative , Wellcome Trust Case-Control Consortium-2 , METASTROKE , Sharma, Pankaj , Fornage, Miriam , Mitchell, Braxton D. , Psaty, Bruce M. , Sudlow, Cathie , Biffi, Alessandro , Levi, Christopher , Boncoraglio, Giorgio B. , Rothwell, Peter M. , Meschia, James , Dichgans, Martin , Rosand, Jonathan , Markus, Hugh S. , Lanfranconi, Silvia , Fitzpatrick, Kaitlin , Bevan, Steve , Kanakis, Allison , Valant, Valerie
- Resource Type: journal article
- Date: 2013
Genome-wide analysis of blood pressure variability and ischemic stroke
- Creator: Yadav, Sunaina , Cotlarciuc, Ioana , Holliday, Elizabeth G. , Speed, Douglas , Hasan, Nazeeha , Pucek, Mateusz , Rinne, Paul E. , Sever, Peter , Stanton, Alice , Shields, Denis C. , Maguire, Jane M. , McEvoy, Mark , Munroe, Patricia B. , Scott, Rodney J. , Ferrucci, Luigi , Macleod, Mary J. , Attia, John , Markus, Hugh S. , Sale, Michele M. , Worrall, Bradford B. , Mitchell, Braxton D. , Dichgans, Martin , Sudlow, Cathy , Khan, Muhammad S. , Meschia, James F. , Rothwell, Peter M. , Caulfield, Mark , Sharma, Pankaj , International Stroke Genetics Consortium, , Nalls, Michael A. , Bevan, Steve , Cheng, Yu-Ching , Chen, Wei-Min , Malik, Rainer , McCarthy, Nina S.
- Resource Type: journal article
- Date: 2013
Ischemic stroke is associated with the ABO locus: the EuroCLOT Study
- Creator: Williams, Frances M. K. , Carter, Angela M. , Sudlow, Cathie , Farrall, Martin , Silander, Kaisa , Kaunisto, Mari , Wagner, Peter , Saarela, Olli , Kuulasmaa, Kari , Virtamo, Jarmo , Salomaa, Veikko , Amouyel, Philippe , Hysi, Pirro G. , Bis, Joshua C. , Levi, Christopher , Attia, John , Holliday, Elizabeth G. , Scott, Rodney J. , Surdulescu, Gabriela , Hodgkiss, Dylan , Soranzo, Nicole , Traylor, Matthew , Bevan, Steve , Dichgans, Martin , Rothwell, Peter M. W.
- Resource Type: journal article
- Date: 2013
Genetic risk factors for ischaemic stroke and its subtypes (the METASTROKE Collaboration): a meta-analysis of genome-wide association studies
- Creator: Traylor, Matthew , Farrall, Martin , Thorsteinsdottir, Unnur , Nalls, Mike A. , Longstreth, W. T. , Wiggins, Kerri L. , Yadav, Sunaina , Parati, Eugenio A. , Destefano, Anita L. , Worrall, Bradford B. , Kittner, Steven J. , Khan, Muhammad Saleem , Holliday, Elizabeth G. , Reiner, Alex P. , Helgadottir, Anna , Achterberg, Sefanja , Fernandez-Cadenas, Israel , Abboud, Sherine , Schmidt, Reinhold , Walters, Matthew , Chen, Wei-Min , Ringelstein, E. Bernd , O'Donnell, Martin , Sudlow, Cathie , Ho, Weang Kee , Pera, Joanna , Lemmens, Robin , Norrving, Bo , Higgins, Peter , Benn, Marianne , Sale, Michele , Kuhlenbaumer, Gregor , Doney, Alexander S. F. , Vicente, Astrid M. , Hopewell, Jemma C. , Delavaran, Hossein , Algra, Ale , Davies, Gail , Oliveira, Sophia A. , Palmer, Colin N. A. , Deary, Ian , Schmidt, Helena , Pandolfo, Massimo , Montaner, Joan , Carty, Cara , Cheng, Yu-Ching , De Bakker, Paul I. W. , Kostulas, Konstantinos , Ferro, Jose M. , Van Zuydam, Natalie R. , Valdimarsson, Einar , Nordestgaard, Berge G. , Lindgren, Anne , Thijs, Vincent , Slowik, Agnieszka , Saleheen, Danish , Fornage, Myriam , Paré, Guillaume , Berger, Klaus , Thorleifsson, Gudmar , Astc, W. , Hofman, Albert , Mosley, Thomas H. , Mitchell, Branxton D. , Furie, Karen , Clarke, Robert , Levi, Christopher , Arfan Ikram, M, , Seshadri, Sudha , Gschwendtner, Andreas , Boncoraglio, Giorgio B. , Sharma, Pankaj , Bis, Joshua C. , Gretarsdottir, Solveig , Psaty, Bruce M. , Rothwell, Peter M. , Rosand, Jonathan , Meschia, James F. , Malik, Rainer , Stefansson, Kari , Dichgans, Martin , Markus, Hugh S. , Bevan, Steve
- Resource Type: journal article
- Date: 2012
Genome-wide association study identifies a variant in HDAC9 associated with large vessel ischemic stroke
- Creator: Bellenguez, Céline , Bevan, Steve , Band, Gavin , Syme, Paul D. , Malik, Rainer , Pera, Joanna , Norrving, Bo , Lemmens, Robin , Freeman, Colin , Schanz, Renata , James, Tom , Poole, Deborah , Gschwendtner, Andreas , Murphy, Lee , Segal, Helen , Cortellini, Lynelle , Cheng, Yu-Ching , Woo, Daniel , Nalls, Michael A. , Müller-Myhsok, Bertram , Meisinger, Christa , Seedorf, Udo , Ross-Adams, Helen , Spencer, Chris C. A. , Boonen, Steven , Wloch-Kopec, Dorota , Valant, Valerie , Slark, Julia , Furie, Karen , Delavaran, Hossein , Langford, Cordelia , Deloukas, Panos , Edkins, Sarah , Hunt, Sarah , Burgess, Annette I. , Gray, Emma , Dronov, Serge , Peltonen, Leena , Gretarsdottir, Solveig , Thorleifsson, Gudmar , Thorsteinsdottir, Unnur , Stefansson, Kari , Boncoraglio, Giorgio B. , Parati, Eugenio A. , Attia, John , Pirinen, Matti , Holliday, Elizabeth , Levi, Chris , Franzosi, Maria-Grazia , Goel, Anuj , Helgadottir, Anna , Blackwell, Jenefer M. , Bramon, Elvira , Brown, Matthew A. , Casas, Juan P. , Corvin, Aiden , Jackson, Caroline A. , Duncanson, Audrey , Jankowski, Janusz , Mathew, Christopher G. , Palmer, Colin N. A. , Plomin, Robert , Rautanen, Anna , Sawcer, Stephen J. , Trembath, Richard C. , Viswanathan, Ananth C. , Wood, Nicholas W. , Traylor, Matthew , Worrall, Bradford B. , Kittner, Steven J. , Mitchell, Braxton D. , Kissela, Brett , Meschia, James F. , Thijs, Vincent , Lindgren, Arne , Macleod, Mary Joan , Slowik, Agnieszka , Walters, Matthew , Strange, Amy , Rosand, Jonathan , Sharma, Pankaj , Farrall, Martin , Sudlow, Cathie L. M. , Rothwell, Peter M. , Dichgans, Martin , Donnelly, Peter , Markus, Hugh S. , Su, Zhan
- Resource Type: journal article
- Date: 2012