Mendelian randomization analysis does not support causal associations of birth weight with hypertension risk and blood pressure in adulthood
- Creator: Zheng, Yan , Huang, Tao , Tai, E-Shyong , Koh, Woon-Puay , Dorajoo, Rajkumar , Saw, Seang-Mei , Sabanayagam, Charumathi , Wong, Tien Yin , Gupta, Preeti , Rossing, Peter , Ahluwalia, Tarunveer S. , Vinding, Rebecca K. , Wang, Tiange , Bisgaard, H , Bønnelykke, K , Wang, Y , Graff, M , Voortman, T , van Rooij, FJA , Hofman, A , van Heemst, D , Noordam, R , Estampador, AC , Mei, Zhendong , Varga, TV , Enzenbach, C , Scholz, M , Thiery, J , Burkhardt, R , Orho-Melander, M , Schulz, CA , Ericson, U , Sonestedt, E , Kubo, M , Sun, Zhonghan , Akiyama, M , Zhou, A , Kilpeläinen, TO , Hansen, T , Kleber, ME , Delgado, G , McCarthy, M , Lemaitre, RN , Felix, JF , Jaddoe, VWV , Zhang, Tao , Wu, Y , Mohlke, KL , Lehtimäki, T , Wang, Carol A. , Pennell, CE , Schunkert, H , Kessler, T , Zeng, L , Willenborg, C , Peters, A , Ellervik, Christina , Lieb, W , Grote, V , Rzehak, P , Koletzko, B , Erdmann, J , Munz, M , Wu, T , He, M , Yu, C , Lecoeur, C , Chai, Jin-Fang , Froguel, P , Corella, D , Moreno, LA , Lai, CQ , Pitkänen, N , Boreham, CA , Ridker, PM , Rosendaal, FR , de Mutsert, R , Power, C , Sim, Xueling , Paternoster, L , Sørensen, TIA , Tjønneland, A , Overvad, K , Djousse, L , Rivadeneira, F , Lee, NR , Raitakari, OT , Kähönen, M , Viikari, J , van Dam, Rob M. , Langhendries, JP , Escribano, J , Verduci, E , Dedoussis, G , König, I , Balkau, B , Coltell, O , Dallongeville, J , Meirhaeghe, A , Amouyel, P
- Resource Type: journal article
- Date: 2020
Association of Birth Weight With Type 2 Diabetes and Glycemic Traits: A Mendelian Randomization Study
- Creator: Huang, Tao , Wang, Tiange , Voortman, Trudy , Sabanayagam, C , Tai, E-S , Mohlke, KL , Mackey, DA , Gruszfeld, D , Deloukas, P , Tucker, KL , Fumeron, F , Bonnelykke, K , Rossing, P , Noordam, Raymond , Estruch, R , Ordovas, JM , Arnett, DK , Meirhaeghe, A , Amouyel, P , Cheng, C-Y , Sim, X , Teo, YY , van Dam, RM , Koh, W-P , Frazier-Wood, Alexis , Orho-Melander, M , Loeffler, M , Kubo, M , Thiery, J , Mook-Kanamori, DO , Mozaffarian, D , Psaty, BM , Franco, OH , Wu, T , North, KE , Scholz, Markus , Smith, GD , Chavarro, JE , Chasman, DI , Qi, L , Sonestedt, Emily , Akiyama, Masato , Dorajoo, Rajkumar , Zhou, Ang , Kilpeläinen, Tuomas O. , Kleber, Marcus E. , Zheng, Yan , Wang, Carol A. , Godfrey, KM , Lemaitre, R , Felix, JF , Shi, Y , Gupta, P , Khor, C-C , Lehtimaki, T , Wang, CA , Tiesler, CMT , Ellervik, Christina , Thiering, E , Standl, M , Rzehak, P , Marouli, E , He, M , Lecoeur, C , Corella, D , Lai, C-Q , Moreno, LA , Pitkanen, N , Li, Xiang , Boreham, CA , Zhang, T , Saw, SM , Ridker, PM , Graff, M , Van Rooij, FJA , Uitterlinden, AG , Hofman, A , van Heemst, D , Rosendaal, FR , Gao, Meng , de Mutsert, R , Burkhardt, R , Schulz, C-A , Ericson, U , Kamatani, Y , Yuan, J-M , Power, C , Hansen, T , Sorensen, TIA , Tjonneland, A , Fang, Zhe , Overvad, K , Delgado, G , Cooper, C , Djousse, L , Rivadeneira, F , Jameson, K , Zhao, W , Liu, J , Lee, NR , Raitakari, O , Chai, Jin-Fang , Kahonen, M , Viikari, J , Grote, V , Langhendries, J-P , Koletzko, B , Escribano, J , Verduci, E , Dedoussis, G , Yu, C , Tham, YC , Ahluwalia, Tarun veer S. , Lim, B , Lim, SH , Froguel, P , Balkau, B , Fink, NR , Vinding, RK , Sevelsted, A , Bisgaard, H , Coltell, O , Dallongeville, J , Wang, Yujie , Gottrand, F , Pahkala, K , Niinikoski, H , Hypponen, E , Pedersen, O , Marz, W , Inskip, H , Jaddoe, VV , Dennison, E , YinWong, T
- Resource Type: journal article
- Date: 2019
Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution
- Creator: Justice, Anne E. , Karaderi, Tugce , Highland, Heather M. , Young, Kristin L. , Graff, Mariaelisa , Lu, Yingchang , Turcot, Valérie , Auer, Paul L. , Fine, Rebeccaa S. , Guo, Xiuqing , Schurmann, Claudia , Lempradl, Adelheid , Marouli, Eirini , Mahajan, Anubha , Winkler, Thomas W. , Locke, Adam E. , Medina-Gomez, Carolina , Esko, Tõnu , Vedantam, Sailaja , Giri, Ayush , Pennell, Craig E. , Wang, Carol A. , Lo, Ken Sin , Alfred, T , Mudgal, P , Ng, MCY , Heard-Costa, NL , Feitosa, MF , Manning, AK , Willems, SM , Sivapalaratnam, S , Abecasis, G , Alam, DS , Allison, M , Amouyel, P , Arzumanyan, Z , Balkau, B , Bastarache, L , Bergmann, S , Bielak, LF , Blüher, M , Boehnke, M , Boeing, H , Boerwinkle, E , Böger, CA , Bork-Jensen, J , Bottinger, EP , Bowden, DW , Brandslund, I , Broer, L , Burt, AA , Butterworth, AS , Caulfield, MJ , Cesana, G , Chambers, JC , Chasman, DI , Chen, YDI , Chowdhury, R , Christensen, C , Chu, AY , Collins, FS , Cook, JP , Cox, AJ , Crosslin, DS , Danesh, J , de Bakker, PIW , Denus, SD , Mutsert, RD , Dedoussis, G , Demerath, EW , Dennis, JG , Denny, JC , Angelantonio, ED , Dörr, M , Drenos, F , Dubé, MP , Dunning, AM , Easton, DF , Elliott, P , Evangelou, E , Farmaki, AE , Feng, S , Ferrannini, E , Ferrieres, J , Florez, JC , Fornage, M , Fox, CS , Franks, PW , Friedrich, N , Gan, W , Gandin, I , Gasparini, P , Giedraitis, V , Girotto, G , Gorski, M , Grallert, H , Grarup, N , Grove, ML , Gustafsson, S , Haessler, J , Hansen, T , Hattersley, AT
- Resource Type: journal article
- Date: 2019
Serum magnesium and calcium levels in relation to ischemic stroke: mendelian randomization study
- Creator: Larsson, Susanna C. , Traylor, Matthew , Okada, Y , Levi, Christopher R. , Mishra, A , Rutten-Jacobs, L , Giese, AK , Van Der Laan, SW , Gretarsdottir, S , Anderson, CD , Chong, M , Adams, HHH , Ago, T , Burgess, Stephen , Almgren, P , Amouyel, P , Ay, H , Bartz, RM , Benavente, OR , Bevan, S , Brown, RD , Butterworth, AS , Carrera, C , Carty, CL , Boncoraglio, Giorgio B. , Chasman, DI , Chen, WM , Cole, JW , Correa, A , Cotlarciuc, I , Cruchaga, C , Danesh, J , De Bakker, PIW , Destefano, AL , Hoed, MD , Jern, Christina , Duan, Q , Engelter, ST , Falcone, GJ , Gottesman, RF , Grewal, RP , Gudnason, V , Gustafsson, S , Haessler, J , Harris, TB , Hassan, A , Michaëlsson, Karl , Havulinna, AS , Heckbert, SR , Holliday, Elizabeth G. , Howard, G , Hsu, FC , Hyacinth, HI , Ikram, MA , Ingelsson, E , Irvin, MR , Jian, X , Markus, Hugh S. , Jiménez-Conde, J , Johnson, JA , Jukema, JW , Kanai, M , Keene, KL , Kissela, BM , Kleindorfer, DO , Kooperberg, C , Kubo, M , Lange, LA , Malik, R , Langefeld, CD , Langenberg, C , Launer, LJ , Lee, JM , Lemmens, R , Leys, D , Lewis, CM , Lin, WY , Lindgren, AG , Lorentzen, E , Chauhan, G , Magnusson, PK , Maguire, J , Manichaikul, A , McArdle, PF , Meschia, JF , Mitchell, BD , Mosley, TH , Nalls, MA , Ninomiya, T , O'Donnell, MJ , Sargurupremraj, M , Psaty, BM , Pulit, SL , Rannikmäe, K , Reiner, AP , Rexrode, KM , Rice, K , Rich, SS , Ridker, PM , Rost, NS , Rothwell, PM
- Resource Type: journal article
- Date: 2019
Trans-ethnic association study of blood pressure determinants in over 750,000 individuals
- Creator: Giri, Ayush , Hellwege, Jacklyn N. , Keaton, Jacob M. , Park, Jihwan , Qiu, Chengxiang , Warren, Helen R. , Torstenson, Eric S. , Kovesdy, Csaba P. , Sun, Yan V. , Wilson, Otis D. , Robinson-Cohen, Cassianne , Roumie, Christianne L. , Chung, Cecilia P. , Birdwell, Kelly A. , Damrauer, Scott M. , DuVall, Scott L. , Klarin, Derek , Cho, Kelly , Wang, Yu , Evangelou, Evangelos , Attia, John , Oldmeadow, Christopher , Wei, WQ , Jarvelin, MR , Hennig, BJ , Timpson, NJ , Smith, JC , Xu, Y , Matheny, ME , Siew, EE , Lindgren, C , Herzig, KH , Dedoussis, G , Denny, JC , Psaty, BM , Howson, JMM , Munroe, PB , Newton-Cheh, C , Caulfield, MJ , Elliott, P , Gaziano, JM , Concato, J , Wilson, PWF , Tsao, PS , Velez Edwards, DR , Susztak, K , O¿Donnell, CJ , Hung, AM , Edwards, TL , Cabrera, Claudia P. , Wain, LV , Shrestha, R , Mautz, BS , Akwo, EA , Sargurupremraj, M , Debette, S , Boehnke, M , Scott, LJ , Luan, J , Zhao, JH , Willems, SM , Thériault, S , Shah, N , Almgren, P , Li-Gao, R , Verweij, N , Boutin, TS , Mangino, M , Ntalla, I , Feofanova, E , Surendran, P , Cook, JP , Karthikeyan, S , Lahrouchi, N , Liu, C , Sepúlveda, N , Richardson, TG , Kraja, A , Amouyel, P , Farrall, M , Poulter, NR , Laakso, M , Zeggini, E , Sever, P , Scott, RA , Langenberg, C , Wareham, NJ , Conen, D , Palmer, CNA , Chasman, DI , Ridker, PM , Melander, O , Mook-Kanamori, DO , van der Harst, P , Cucca, F , Schlessinger, D , Hayward, C , Spector, TD
- Resource Type: journal article
- Date: 2019
Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits
- Creator: Evangelou, Evangelos , Warren, Helen R. , Ng, Fu Liang , Evangelou, Marina , Witkowska, Katarzyna , Tzanis, Evan , Hellwege, Jacklyn N. , Giri, Ayush , Velez Edwards, Digna R. , Sun, Yan V. , Cho, Kelly , Gaziano, J. Michael , Mosen-Ansorena, David , Wilson, Peter W. F. , Tsao, PS , Kovesdy, CP , Esko, T , Mägi, R , Milani, L , Almgren, P , Boutin, T , Debette, S , Ding, J , Mifsud, Borbala , Giulianini, F , Holliday, Elizabeth G. , Jackson, AU , Li-Gao, R , Lin, WY , Luan, J , Mangino, M , Oldmeadow, Christopher , Attia, John R. , Qian, Y , Pazoki, Raha , Sargurupremraj, M , Shah, N , Surendran, P , Thériault, S , Verweij, N , Willems, SM , Zhao, JH , Amouyel, P , Connell, J , de Mutsert, R , Gao, He , Doney, ASF , Farrall, M , Menni, C , Morris, AD , Noordam, R , Paré, G , Poulter, NR , Shields, DC , Stanton, A , Thom, S , Ntritsos, Georgios , Abecasis, G , Amin, N , Arking, DE , Ayers, KL , Barbieri, CM , Batini, C , Bis, JC , Blake, T , Bochud, M , Boehnke, M , Dimou, Niki , Boerwinkle, E , Boomsma, DI , Bottinger, EP , Braund, PS , Brumat, M , Campbell, A , Campbell, H , Chakravarti, A , Chambers, JC , Cabrera, Claudia P. , Karaman, Ibrahim
- Resource Type: journal article
- Date: 2018
Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function
- Creator: Davies, Gail , Lam, Max , Liewald, David C. M. , Knopman, DS , Kochan, NA , Konte, B , Kwok, JB , Le Hellard, S , Lee, T , Lehtimaki, T , Li, S-C , Liu, T , Koini, M , Okely, Judith A. , London, E , Longstreth, WT , Lopez, OL , Loukola, A , Luck, T , Lundervold, AJ , Lundquist, A , Lyytikainen, L-P , Martin, NG , Montgomery, GW , Ahola-Olli, Ari V. , Murray, AD , Need, AC , Noordam, R , Nyberg, L , Ollier, W , Papenberg, G , Pattie, A , Polasek, O , Poldrack, RA , Psaty, BM , Barnes, Catriona L. K. , Reppermund, S , Riedel-Heller, SG , Rose, RJ , Rotter, JI , Roussos, P , Rovio, SP , Saba, Y. , Sabb, FW , Sachdev, PS , Satizabal, CL , Bertram, Lars , Schmid, M , Scott, Rodney J. , Scult, MA , Simino, J , Slagboom, PE , Smyrnis, N , Soumare, A , Stefanis, NC , Stott, DJ , Straub, RE , Bis, Joshua C. , Sundet, K , Taylor, AM , Taylor, KD , Tzoulaki, I , Tzourio, C , Uitterlinden, A , Vitart, V , Voineskos, AN , Kaprio, J , Wagner, M , Burdick, Katherine E. , Wagner, H , Weinhold, L , Wen, KH , Widen, E , Yang, Q , Zhao, W , Adams, HHH , Arking, DE , Bilder, RM , Bitsios, P , Christoforou, Andrea , Boerwinkle, E , Chiba-Falek, O , Corvin, A , De Jager, PL , Debette, S , Donohoe, G , Elliott, P , Fitzpatrick, AL , Gill, M , Glahn, DC , DeRosse, Pamela , Hagg, S , Hansell, NK , Hariri, AR , Ikram, MK , Jukema, JW , Vuoksimaa, E , Keller, MC , Kremen, WS , Launer, L , Lindenberger, U , Djurovic, Srdjan , Palotie, A , Pedersen, NL , Pendleton, N , Porteous, DJ , Raikkonen, K , Raitakari, OT , Ramirez, A , Reinvang, I , Rudan, I , Rujescu, D , Harris, Sarah E. , Espeseth, Thomas , Schmidt, R , Schmidt, H , Schofield, PW , Schofield, PR , Starr, JM , Steen, VM , Trollor, JN , Turner, ST , Van Duijn, CM , Villringer, A , Giakoumaki, Stella , Weinberger, DR , Weir, DR , Wilson, JF , Malhotra, A , McIntosh, AM , Gale, CR , Seshadri, S , Mosley, TH , Bressler, J , Lencz, T , Giddaluru, S , Deary, IJ , Gustavson, DE , Hayward, C , Hofer, E , Ikram, MA , Karlsson, R , Knowles, E , Lahti, J , Trampush, Joey W. , Leber, M , Li, S , Mather, KA , Melle, I , Morris, D , Oldmeadow, Christopher , Palviainen, T , Payton, A , Pazoki, R , Petrovic, K , Luciano, Michelle , Reynolds, CA , Sargurupremraj, M , Scholz, M , Smith, JA , Smith, AV , Terzikhan, N , Thalamuthu, A , Trompet, S , van der Lee, SJ , Ware, EB , Hill, W. David , Windham, BG , Wright, MJ , Yang, J , Yu, J , Ames, D , Amin, N , Amouyel, P , Andreassen, OA , Armstrong, NJ , Assareh, AA , Hagenaars, Saskia P. , Attia, John R. , Attix, D , Avramopoulos, D , Bennett, DA , Boehmer, AC , Boyle, PA , Brodaty, H , Campbell, H , Cannon, TD , Cirulli, ET , Ritchie, Stuart J. , Congdon, E , Conley, ED , Corley, J , Cox, SR , Dale, AM , Dehghan, A , Dick, D , Dickinson, D , Eriksson, JG , Evangelou, E , Marioni, Riccardo E. , Faul, JD , Ford, I , Freimer, NA , Gao, H , Giegling, I , Gillespie, NA , Gordon, SD , Gottesman, RF , Griswold, ME , Gudnason, V , Fawns-Ritchie, Chloe , Harris, TB , Hartmann, AM , Hatzimanolis, A , Heiss, G , Holliday, Elizabeth G. , Joshi, PK , Kahonen, M , Kardia, SLR , Karlsson, I , Kleineidam, L
- Resource Type: journal article
- Date: 2018