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RYR2 channel inhibition is the principal mechanism of flecainide action in CPVT
- Kryshtal, Dmytro O., Blackwell, Daniel J., Egly, Christian L., Smith, Abigail N., Batiste, Suzanne M., Johnston, Jeffrey N., Laver, Derek R., Knollmann, Bjorn C.
Mechanisms of cardiac ryanodine receptor inhibition by anti arrhythmic drugs
- Mehra, Divya Rajendra
Multiple modes of ryanodine receptor 2 inhibition by flecainide
- Mehra, D., Imtiaz, M. S., van Helden, D. F., Knollmann, B. C., Laver, D. R.
Inhibition of cardiac Ca²⁺ release channels (RyR2) determines efficacy of class I antiarrhythmic drugs in catecholaminergic polymorphic ventricular tachycardia
- Hwang, Hyun Seok, Hasdemir, Can, Laver, Derek, Mehra, Divya, Turhan, Kutsal, Faggioni, Michela, Yin, Huiyong, Knollmann, Björn C.
Flecainide inhibits arrhythmogenic Ca²⁺ waves by open state block of ryanodine receptor Ca²⁺ release channels and reduction of Ca²⁺ spark mass
- Hilliard, Fredrick A., Steele, Derek S., Laver, Derek, Yang, Zhaokang, Le Marchand, Sylvain J., Chopra, Nagesh, Piston, David W., Huke, Sabine, Knollmann, Björn C.
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