Amitriptyline activates cardiac ryanodine channels and causes spontaneous sarcoplasmic reticulum calcium release

- Chopra, Nagesh, Laver, Derek, Davies, Sean S., Knollmann, Björn C.

Calmodulin inhibition of human RyR2 channels requires phosphorylation of RyR2-S2808 or RyR2-S2814

- Walweel, Kafa, Gomez-Hurtado, Nieves, Laver, Derek R., Rebbeck, Robyn T., Oo, Ye Wint, Beard, Nicole A., Molenaar, Peter, dos Remedios, Chris, van Helden, Dirk F., Cornea, Razvan L., Knollmann, Björn C.

Divergent regulation of ryanodine receptor 2 calcium release channels by arrhythmogenic human calmodulin missense mutants

- Hwang, Hyun Seok, Nitu, Florentin R., Cornea, Razvan L., Bers, Donald M., Knollmann, Björn C., Yang, Yi, Walweel, Kafa, Pereira, Laetitia, Johnson, Christopher N., Faggioni, Michela, Chazin, Walter J., Laver, Derek, George Jr, Alfred L.

Flecainide inhibits arrhythmogenic Ca²⁺ waves by open state block of ryanodine receptor Ca²⁺ release channels and reduction of Ca²⁺ spark mass

- Hilliard, Fredrick A., Steele, Derek S., Laver, Derek, Yang, Zhaokang, Le Marchand, Sylvain J., Chopra, Nagesh, Piston, David W., Huke, Sabine, Knollmann, Björn C.

Flecainide prevents catecholaminergic polymorphic ventricular tachycardia in mice and humans

- Watanabe, Hiroshi, Chopra, Nagesh, Laver, Derek, Hwang, Hyun Seok, Davies, Sean S., Roach, Daniel E., Duff, Henry J., Roden, Dan M., Wilde, Arthur A. M., Knollmann, Björn C.

Inhibition of cardiac Ca²⁺ release channels (RyR2) determines efficacy of class I antiarrhythmic drugs in catecholaminergic polymorphic ventricular tachycardia

- Hwang, Hyun Seok, Hasdemir, Can, Laver, Derek, Mehra, Divya, Turhan, Kutsal, Faggioni, Michela, Yin, Huiyong, Knollmann, Björn C.