17q25 Locus is associated with white matter hyperintensity volume in ischemic stroke, but not with lacunar stroke status

- Adib-Samii, Poneh, Rost, Natalia, Gschwendtner, Andreas, Malik, Rainer, Richie, Alexa, Gamble, Dale, Segal, Helen, Parati, Eugenio A., Ciusani, Emilio, Holliday, Elizabeth G., Maguire, Jane, Wardlaw, Joanna, Traylor, Matthew, Worrall, Bradford, Bis, Joshua, Wiggins, Kerri L., Longstreth, Will, Kittner, Steve J., Cheng, Yu-Ching, Mosley, Thomas, Falcone, Guido J., Furie, Karen L., Leiva-Salinas, Carlos, Devan, William, Lau, Benison C., Saleem Khan, Muhammed, Australian Stroke Genetics Collaborative, Wellcome Trust Case-Control Consortium-2, METASTROKE, Sharma, Pankaj, Fornage, Miriam, Mitchell, Braxton D., Psaty, Bruce M., Sudlow, Cathie, Biffi, Alessandro, Levi, Christopher, Boncoraglio, Giorgio B., Rothwell, Peter M., Meschia, James, Dichgans, Martin, Rosand, Jonathan, Markus, Hugh S., Lanfranconi, Silvia, Fitzpatrick, Kaitlin, Bevan, Steve, Kanakis, Allison, Valant, Valerie

A novel MMP12 locus Is associated with large artery atherosclerotic stroke using a genome-wide age-at-onset informed approach

- Traylor, Matthew, Mäkelä, Kari-Matti, Malik, Rainer, Sudlow, Cathie, Bevan, Steve, Raitoharju, Emma, Oksala, Niku, Thijs, Vincent, Lemmens, Robin, Lindgren, Arne, Slowik, Agnieszka, Kilarski, Laura L., Maguire, Jane M., Walters, Matthew, Algra, Ale, Sharma, Pankaj, Attia, John R., Boncoraglio, Giorgio B., Rothwell, Peter M., de Bakker, Paul I. W., Bis, Joshua C., Saleheen, Danish, Holliday, ELizabeth G., Kittner, Steven J., Mitchell, Braxton D., Rosand, Jonathan, Meschia, James F., Levi, Christopher, Dichgans, Martin, Lehtimäki, Terho, Lewis, Cathryn M., Markus, Hugh S., Devan, William J., Nalls, Mike A., Wiggins, Kerri L., Zhao, Wei, Cheng, Yu-Ching, Achterberg, Sefanja

Association of MTHFR C677T genotype with ischemic stroke is confined to cerebral small vessel disease subtype

- Rutten-Jacobs, Loes C. A., Traylor, Matthew, Levi, Christopher, Rost, Natalia S., Rosand, Jonathan, Hassan, Ahamad, Bevan, Steve, Markus, Hugh S., Adib-Samii, Ppneh, Thijs, Vincent, Sudlow, Cathie, Rothwell, Peter M., Boncoraglio, Giorgio, Dichgans, Martin, Meschia, James, Maguire, Jane

Common coding variant in SERPINA1 increases the risk for large artery stroke

- Malik, Rainer, Cardenas, IF, Rothwell, PM, Levi, C, Attia, J, Sudlow, CLM, Braun, D, Markus, HS, Wintrode, PL, Berger, K, Jenne, DE, Dichgans, M, Dau, Therese, Seixas, Susana, Bevan, Steve, Lincz, Lisa F., Holliday, Elizabeth G., Burgess, Annette I., Rannikmäe, Kristiina, Minnerup, Jens, Kriebel, Jennifer, Waldenberger, Melanie, Müller-Nurasyid, Martina, Gonik, Maria, Levi, Christopher, Attia, John, Maguire, Jane, Sivakumar, Anirudh, Deredge, Daniel J., Edeleva, Evgeniia V., Götzfried, Jessica, van der Laan, Sander W., Pasterkamp, Gerard, Beaufort, Nathalie

Common NOTCH3 variants and cerebral small-vessel disease

- Rutten-Jacobs, Loes C. A., Traylor, Matthew, Levi, Christopher, Rost, Natalia S., Rosand, Jonathan, Hassan, Ahamad, Markus, Hugh S., Adib-Samii, Poneh, Thijs, Vincent, Sudlow, Cathie, Rothwell, Peter M., Boncoraglio, Giorgio, Dichgans, Martin, Bevan, Steve, Meschia, James

Common variants at 6p21.1 are associated with large artery atherosclerotic stroke

- Holliday, Elizabeth G., Maguire, Jane M., Malik, Rainer, McEvoy, Mark, Biros, Erik, Lewis, Martin D., Lincz, Lisa F., Peel, Roseanne, Oldmeadow, Christopher, Smith, Wayne, Moscato, Pablo, Barlera, Simona, Evans, Tiffany-Jane, Bevan, Steve, Bis, Joshua C., Boerwinkle, Eric, Boncoraglio, Giorgio B., Brott, Thomas G., Scott, Rodney J., Levi, Christopher, Attia, John, Koblar, Simon A., Jannes, Jim, Sturm, Jonathan W., Hankey, Graeme J., Baker, Ross, Golledge, Jonathan, Parsons, Mark W.

Common variation in COL4A1/COL4A2 is associated with sporadic cerebral small vessel disease

- Rannikmäe, Kristiina, Davies, Gail, Deka, Ranjan, Woo, Jessica G., Martin, Lisa J., Jimenez-Conde, Jordi, Selim, Magdy, Brown, Devin L., Silliman, Scott L., Kidwell, Chelsea S., Montaner, Joan, Langefeld, Carl D., Thomson, Pippa A., Holliday, Elizabeth G., Levi, Christopher R., Attia, John, Rothwell, Peter M., Poole, Deborah L., Bevan, Steve, Devan, William J., Falcone, Guido J., Traylor, Matthew, Anderson, Christopher D., Battey, Thomas W. K., Radmanesh, Farid

Differences in common genetic predisposition to ischemic stroke by age and sex

- Traylor, Matthew, Rutten-Jacobs, Loes C. A., Dichgans, Martin, Levi, Chris, Lewis, Cathryn M., Markus, Hugh S., Holliday, Elizabeth G., Malik, Rainer, Sudlow, Cathie, Rothwell, Peter M., Maguire, Jane M., Koblar, Simon A., Bevan, Steve, Boncoraglio, Giorgio

Genetic architecture of white matter hyperintensities differs in hypertensive and nonhypertensive ischemic stroke

- Adib-Samii, Poneh, Devan, William, Rothwell, Peter M., Sudlow, Cathie, Boncoraglio, Giorgio B., Meschia, James F., Levi, Chris, Dichgans, Martin, Bevan, Steve, Rosand, Jonathan, Rost, Natalia S., Markus, Hugh S., Traylor, Matthew, Lanfranconi, Silvia, Zhang, Cathy R., Cloonan, Lisa, Falcone, Guido J., Radmanesh, Farid, Fitzpatrick, Kaitlin, Kanakis, Allison

Genetic associations with white matter hyperintensities confer risk of lacunar stroke

- Traylor, Matthew, Rutten-Jacobs, Loes C. A., Dichgans, Martin, Markus, Hugh S., Thijs, Vincent, Holliday, Elizabeth G., Levi, Chris, Bevan, Steve, Malik, Rainer, Boncoraglio, Giorgio, Sudlow, Cathie, Rothwell, Peter M.

Genetic imbalance is associated with functional outcome after Ischemic Stroke

- Pfeiffer, Dorothea, Chen, Bowang, Schlicht, Kristina, Ginsbach, Philip, Abboud, Sherine, Bersano, Anna, Bevan, Steve, Brandt, Tobias, Caso, Valeria, Debette, Stephanie, Erhart, Philipp, Freitag-Wolf, Sandra, Giacalone, Giacomo, Grau, Armin J., Hayani, Eyad, Jern, Christina, Jiménez-Conde, Jordi, Kloss, Manja, Krawczak, Michael, Lee, Jin-Moo, Maguire, Jane M.

Genetic overlap between diagnostic subtypes of ischemic stroke

- Holliday, Elizabeth G., Traylor, Matthew, Boncoraglio, Giorgio B., Clarke, Robert, Cole, John W., Fornage, Myriam, Furie, Karen L., Ikram, M. Arfan, Jannes, Jim, Kittner, Steven J., Lincz, Lisa F., Maguire, Jane M., Malik, Rainer, Oldmeadow, Christopher, Scott, Rodney J., Levi, Christopher, Attia, John, Bevan, Steve, Falcone, Guido, Hopewell, Jemma C., Cheng, Yu-Ching, Cotlarciuc, Ioana, Bis, Joshua C., Boerwinkle, Eric

Genetic risk factors for ischaemic stroke and its subtypes (the METASTROKE Collaboration): a meta-analysis of genome-wide association studies

- Traylor, Matthew, Farrall, Martin, Thorsteinsdottir, Unnur, Nalls, Mike A., Longstreth, W. T., Wiggins, Kerri L., Yadav, Sunaina, Parati, Eugenio A., Destefano, Anita L., Worrall, Bradford B., Kittner, Steven J., Khan, Muhammad Saleem, Holliday, Elizabeth G., Reiner, Alex P., Helgadottir, Anna, Achterberg, Sefanja, Fernandez-Cadenas, Israel, Abboud, Sherine, Schmidt, Reinhold, Walters, Matthew, Chen, Wei-Min, Ringelstein, E. Bernd, O'Donnell, Martin, Sudlow, Cathie, Ho, Weang Kee, Pera, Joanna, Lemmens, Robin, Norrving, Bo, Higgins, Peter, Benn, Marianne, Sale, Michele, Kuhlenbaumer, Gregor, Doney, Alexander S. F., Vicente, Astrid M., Hopewell, Jemma C., Delavaran, Hossein, Algra, Ale, Davies, Gail, Oliveira, Sophia A., Palmer, Colin N. A., Deary, Ian, Schmidt, Helena, Pandolfo, Massimo, Montaner, Joan, Carty, Cara, Cheng, Yu-Ching, De Bakker, Paul I. W., Kostulas, Konstantinos, Ferro, Jose M., Van Zuydam, Natalie R., Valdimarsson, Einar, Nordestgaard, Berge G., Lindgren, Anne, Thijs, Vincent, Slowik, Agnieszka, Saleheen, Danish, Fornage, Myriam, Paré, Guillaume, Berger, Klaus, Thorleifsson, Gudmar, Astc, W., Hofman, Albert, Mosley, Thomas H., Mitchell, Branxton D., Furie, Karen, Clarke, Robert, Levi, Christopher, Arfan Ikram, M,, Seshadri, Sudha, Gschwendtner, Andreas, Boncoraglio, Giorgio B., Sharma, Pankaj, Bis, Joshua C., Gretarsdottir, Solveig, Psaty, Bruce M., Rothwell, Peter M., Rosand, Jonathan, Meschia, James F., Malik, Rainer, Stefansson, Kari, Dichgans, Martin, Markus, Hugh S., Bevan, Steve

Genetics of the thrombomodulin-endothelial cell protein C receptor system and the risk of early-onset ischemic stroke

- Cole, John W., Xu, Huichun, Ryan, Kathleen, Jaworek, Thomas, Dueker, Nicole, McArdle, Patrick, Gaynor, Brady, Cheng, Yu-Ching, O'Connell, Jeffrey, Bevan, Steve, Malik, Rainer, Ahmed, Naveed Uddin, Amouyel, Philippe, Anjum, Sheraz, Bis, Joshua C., Crosslin, David, Danesh, John, Engelter, Stefan T., Fornage, Myriam, Frossard, Philippe, Holliday, Elizabeth, Levi, Christopher

Genome-wide analysis of blood pressure variability and ischemic stroke

- Yadav, Sunaina, Cotlarciuc, Ioana, Holliday, Elizabeth G., Speed, Douglas, Hasan, Nazeeha, Pucek, Mateusz, Rinne, Paul E., Sever, Peter, Stanton, Alice, Shields, Denis C., Maguire, Jane M., McEvoy, Mark, Munroe, Patricia B., Scott, Rodney J., Ferrucci, Luigi, Macleod, Mary J., Attia, John, Markus, Hugh S., Sale, Michele M., Worrall, Bradford B., Mitchell, Braxton D., Dichgans, Martin, Sudlow, Cathy, Khan, Muhammad S., Meschia, James F., Rothwell, Peter M., Caulfield, Mark, Sharma, Pankaj, International Stroke Genetics Consortium,, Nalls, Michael A., Bevan, Steve, Cheng, Yu-Ching, Chen, Wei-Min, Malik, Rainer, McCarthy, Nina S.

Genome-wide association meta-analysis of functional outcome after ischemic stroke

- Söderholm, Martin, Pedersen, Annie, Jood, Katarina, Lee, Jin-Moo, Lemmens, Robin, Levi, Christopher, Mitchell, Braxton D., Norrving, Bo, Rannikmäe, Kristiina, Rost, Natalia S., Rosand, Jonathan, Rothwell, Peter M., Lorentzen, Erik, Scott, Rodney, Strbian, Daniel, Sturm, Jonathan W., Sudlow, Cathie, Traylor, Matthew, Thijs, Vincent, Tatlisumak, Turgut, Woo, Daniel, Worrall, Bradford B., Maguire, Jane M., Stanne, Tara M., Lindgren, Arne, Jern, Christina, Bevan, Steve, Olsson, Maja, Cole, John W., Fernandez-Cadenas, Israel, Hankey, Graeme J., Jimenez-Conde, Jordi

Genome-wide association study identifies a variant in HDAC9 associated with large vessel ischemic stroke

- Bellenguez, Céline, Bevan, Steve, Band, Gavin, Syme, Paul D., Malik, Rainer, Pera, Joanna, Norrving, Bo, Lemmens, Robin, Freeman, Colin, Schanz, Renata, James, Tom, Poole, Deborah, Gschwendtner, Andreas, Murphy, Lee, Segal, Helen, Cortellini, Lynelle, Cheng, Yu-Ching, Woo, Daniel, Nalls, Michael A., Müller-Myhsok, Bertram, Meisinger, Christa, Seedorf, Udo, Ross-Adams, Helen, Spencer, Chris C. A., Boonen, Steven, Wloch-Kopec, Dorota, Valant, Valerie, Slark, Julia, Furie, Karen, Delavaran, Hossein, Langford, Cordelia, Deloukas, Panos, Edkins, Sarah, Hunt, Sarah, Burgess, Annette I., Gray, Emma, Dronov, Serge, Peltonen, Leena, Gretarsdottir, Solveig, Thorleifsson, Gudmar, Thorsteinsdottir, Unnur, Stefansson, Kari, Boncoraglio, Giorgio B., Parati, Eugenio A., Attia, John, Pirinen, Matti, Holliday, Elizabeth, Levi, Chris, Franzosi, Maria-Grazia, Goel, Anuj, Helgadottir, Anna, Blackwell, Jenefer M., Bramon, Elvira, Brown, Matthew A., Casas, Juan P., Corvin, Aiden, Jackson, Caroline A., Duncanson, Audrey, Jankowski, Janusz, Mathew, Christopher G., Palmer, Colin N. A., Plomin, Robert, Rautanen, Anna, Sawcer, Stephen J., Trembath, Richard C., Viswanathan, Ananth C., Wood, Nicholas W., Traylor, Matthew, Worrall, Bradford B., Kittner, Steven J., Mitchell, Braxton D., Kissela, Brett, Meschia, James F., Thijs, Vincent, Lindgren, Arne, Macleod, Mary Joan, Slowik, Agnieszka, Walters, Matthew, Strange, Amy, Rosand, Jonathan, Sharma, Pankaj, Farrall, Martin, Sudlow, Cathie L. M., Rothwell, Peter M., Dichgans, Martin, Donnelly, Peter, Markus, Hugh S., Su, Zhan

Genome-wide meta-analysis of cerebral white matter hyperintensities in patients with stroke

- Traylor, Matthew, Zhang, Cathy R., Fitzpatrick, Kaitlin, Kanakis, Allison, Barrick, Thomas R., Moynihan, Barry, Lewis, Cathryn M., Boncoraglio, Giorgio B., Lemmens, Robin, Thijs, Vincent, Sudlow, Cathie, Wardlaw, Joanna, Adib-Samii, Poneh, Levi, Christopher, Bevan, Steve, Devan, William J., Parsons, Owen E., Lanfranconi, Silvia, Gregory, Sarah, Cloonan, Lisa, Falcone, Guido J., Radmanesh, Fadrid

Investigating the causal relationship of C-reactive protein with 32 complex somatic and psychiatric outcomes: a large-scale cross-consortium mendelian randomization study

- Prins, Bram P., Abbasi, Ali, Valdes, Ana M., Bras, Jose, Shatunov, Aleksey, Lu, Chen, Han, Buhm, Raychaudhuri, Soumya, Bevan, Steve, Mayes, Maureen D., Tsoi, Lam C., Evangelou, Evangelos, Wong, Anson, Nair, Rajan P., Grant, Stuan F. A., Polychronakos, Constantin, Radstake, Timothy R. D., van Heel, David A., Dunstan, Melanie L., Wood, Nicholas W., Al-Chalabi, Ammar, Dehghan, Abbas, Hakonarson, Hakon, Vaez, Ahmad, Markus, Hugh S., Elder, James T., Knight, Jo, Arking, Dan E., Spector, Timothy D., Koeleman, Bobby P. C., van Duijn, Cornelia M., Martin, Javier, Morris, Andrew P., Weersma, Rinse K., Nolte, Ilja, Wijmenga, Cisca, Munroe, Patricia B., Perry, John R. B., Pouget, Jennie G., Jamshidi, Yalda, Snieder, Harold, Alizadeh, Behrooz Z., Tooney, Paul, Franceschini, Nora, Stuart, Philip E., Guterriez Achury, Javier, Mistry, Vanisha, Bradfield, Jonathan P.

Ischemic stroke is associated with the ABO locus: the EuroCLOT Study

- Williams, Frances M. K., Carter, Angela M., Sudlow, Cathie, Farrall, Martin, Silander, Kaisa, Kaunisto, Mari, Wagner, Peter, Saarela, Olli, Kuulasmaa, Kari, Virtamo, Jarmo, Salomaa, Veikko, Amouyel, Philippe, Hysi, Pirro G., Bis, Joshua C., Levi, Christopher, Attia, John, Holliday, Elizabeth G., Scott, Rodney J., Surdulescu, Gabriela, Hodgkiss, Dylan, Soranzo, Nicole, Traylor, Matthew, Bevan, Steve, Dichgans, Martin, Rothwell, Peter M. W.