Genetic risk score mendelian randomization shows that obesity measured as body mass index, but not waist:hip ratio, is causal for endometrial cancer
- Creator: Painter, Jodie N. , O'Mara, Tracy A. , Scott, Rodney J. , Ahmed, Shahana , Healey, Catherine S. , Shah, Mitul , Gorman, Maggie , Martin, Lynn , Hodgson, Shirley V. , Beckmann, Matthias W. , Ekici, Arif B. , Fasching, Peter A. , Marquart, Louise , Hein, Alexander , Rübner, Matthias , Czene, Kamilla , Darabi, Hatef , Hall, Per , Li, Jingmei , Dörk, Thilo , Dürst, Matthias , Hillemanns, Peter , Runnebaum, Ingo B. , Webb, Penelope M. , Amant, Frederic , Annibali, Daniela , Depreeuw, Jeroen , Lambrechts, Diether , Neven, Patrick , Cunningham, Julie M. , Dowdy, Sean C. , Goode, Ellen L. , Fridley, Brooke L. , Winham, Stacey J. , Attia, John , Njølstad, Tormund S. , Salvesen, Helga B. , Trovik, Jone , Werner, Henrica M. J. , Ashton, Katie A. , Otton, Geoffrey , Proietto, Anthony , Mints, Miriam , Tham, Emma , Bolla, Manjeet K. , Medland, Sarah E. , Michailidou, Kyriaki , Wang, Qin , Tyrer, Jonathan P. , Hopper, John L. , Peto, Julian , Swerdlow, Anthony J. , Burwinkel, Barbara , Brenner, Hermann , Meindl, Alfons , Brauch, Hiltrud , Cheng, Timothy , Lindblom, Annika , Chang-Claude, Jenny , Couch, Fergus J. , Giles, Graham G. , Kristensen, Vessela N. , Cox, Angela , Pharoah, Paul D. P. , Tomlinson, Ian , Dunning, Alison M. , Easton, Douglas F. , Dennis, Joe , Thompson, Deborah J. , Spurdle, Amanda B. , Holliday, Elizabeth G. , McEvoy, Mark
- Resource Type: journal article
- Date: 2016
Candidate locus analysis of the TERT-CLPTM1L cancer risk region on chromosome 5p15 identifies multiple independent variants associated with endometrial cancer risk
- Creator: Carvajal-Carmona, Luis G. , O Mara, Tracy A. , Pooley, Karen , Beesley, Jonathan , Cheng, Timothy , Jones, Angela , Howarth, Kimberley , Martin, Lynn , Gorman, Maggie , Hodgson, Shirley , National Study of Endometrial Cancer Genetics Group (NSECG) , . , The Australian National Endometrial Cancer Study Group (ANECS), . , Painter, Jodie N. , Wentzensen, Nicholas , Fasching, Peter A. , Hein, Alexander , Beckmann, Matthias W. , Renner, Stefan P. , Dörk, Thilo , Hillemanns, Peter , Dürst, Matthias , Runnebaum, Ingo , Lambrechts, Diether , Lose, Felicity A. , Coenegrachts, Lieve , Schrauwen, Stefanie , Amant, Frederic , Winterhoff, Boris , Dowdy, Sean C. , Goode, Ellen L. , Teoman, Attila , Salvesen, Helga B. , Trovik, Jone , Njolstad, Tormund S. , Dennis, Joe , Werner, Henrica M. J. , Scott, Rodney J. , Ashton, Katie , Proietto, Tony , Otton, Geoffrey , Wersäll, Ofra , Mints, Miriam , Tham, Emma , RENDOCAS, , Hall, Per , Michailidou, Kyriaki , Czene, Kamila , Liu, Jianjun , Li, Jingmei , Hopper, John L. , Southey, Melissa C. , Australian Ovarian Cancer Study (AOCS), . , Ekici, Arif B. , Ruebner, Matthias , Johnson, Nichola , Peto, Julian , Tyrer, Jonathan P. , Burwinkel, Barbara , Marme, Frederik , Brenner, Hermann , Dieffenbach, Aida K. , Meindl, Alfons , Brauch, Hiltrud , The GENICA Network, . , Lindblom, Annika , Depreeuw, Jeroen , Moisse, Matthieu , Ahmed, Shahana , Chang-Claude, Jenny , Rudolph, Anja , Couch, Fergus J. , Olson, Janet E. , Giles, Graham G. , Bruinsma, Fiona , Cunningham, Julie M. , Fridley, Brooke L. , Børresen-Dale, Anne-Lise , Kristensen, Vessela N. , Ferguson, Kaltin , Cox, Angela , Swerdlow, Anthony J. , Orr, Nicholas , Bolla, Manjeet K. , Wang, Qin , Palmieri Weber, Rachel , Chen, Zhihua , Shah, Mitul , Pharoah, Paul D. P. , Dunning, Alison M. , Healey, Catherine S. , Tomlinson, Ian , Easton, Douglas F. , Spurdle, Amanda B. , Thompson, Deborah J.
- Resource Type: journal article
- Date: 2015
Comprehensive genetic assessment of the ESR1 locus identifies a risk region for endometrial cancer
- Creator: O'Mara, Tracy A. , Glubb, Dylan M. , Ashton, Katie , Proietto, Tony , Otton, Geoffrey , Shah, Mitul , Ahmed, Shahana , Healey, Catherine S. , Gorman, Maggie , Martin, Lynn , National Study of Endometrial Cancer Genetics Group (NSECG), , Hodgson, Shirley , Painter, Jodie N. , Fasching, Peter A. , Hein, Alexander , Beckmann, Matthias W. , Ekici, Arif B. , Hall, Per , Czene, Kamila , Darabi, Hatef , Li, Jingmei , Dürst, Matthias , Runnebaum, Ingo , Cheng, Timothy , Hillemanns, Peter , Dörk, Thilo , Lambrechts, Diether , Depreeuw, Jeroen , Annibali, Daniela , Amant, Frederic , Zhao, Hui , Goode, Ellen L. , Dowdy, Sean C. , Fridley, Brooke L. , Dennis, Joe , Winham, Stacey J. , Salvesen, Helga B. , Njølstad, Tormund S. , Trovik, Jone , Werner, Henrica M. J. , Tham, Emma , Liu, Tao , Mints, Miriam , RENDOCAS, , Bolla, Manjeet K. , Australian National Endometrial Cancer Study Group (ANECS), , Michailidou, Kyriaki , Tyrer, Jonathan P. , Wang, Qin , Hopper, John L. , AOCS Group, , Peto, Julian , Swerdlow, Anthony J. , Burwinkel, Barbara , Brenner, Hermann , Meindl, Alfons , Attia, John , Brauch, Hiltrud , Lindblom, Annika , Chang-Claude, Jenny , Couch, Fergus J. , Giles, Graham G. , Kristensen, Vessela N. , Cox, Angela , Pharoah, Paul D. P. , Dunning, Alison M. , Tomlinson, Ian , Holliday, Elizabeth G. , Easton, Douglas F. , Thompson, Deborah J. , Spurdle, Amanda B. , McEvoy, Mark , Scott, Rodney J.
- Resource Type: journal article
- Date: 2015
Fine-mapping of the HNF1B multicancer locus identifies candidate variants that mediate endometrial cancer risk.
- Creator: Painter, Jodie N. , O'Mara, Tracy A. , Healey, Catherine S. , Fridley, Brooke L. , Børresen-Dale, Anne-Lise , Kristensen, Vessela N. , Cox, Angela , Swerdlow, Anthony J. , Orr, Nicholas , Bolla, Manjeet K. , Wang, Qin , Palmieri Weber, Rachel , Chen, Zhihua , Kaufmann, Susanne , Shah, Mitul , French, Juliet D. , Pharoah, Paul D. P. , Dunning, Alison M. , Tomlinson, Ian , Easton, Douglas F. , Edwards, Stacey L. , Thompson, Deborah J. , Spurdle, Amanda B. , Hillman, Kristine M. , Walpole, Carina , Moya, Leire , Pollock, Pamela , Jones, Angela , Howarth, Kimberley , Martin, Lynn , Gorman, Maggie , Batra, Jyotsna , Hodgson, Shirley , National Study of Endometrial Cancer Genetics Group (NSECG) , CHIBCHA Consortium , De Polanco, Ma. Magdalena Echeverry , Sans, Monica , Carracedo, Angel , Castellvi-Bel, Sergi , Rojas-Martinez, Augusto , Santos, Erika , Teixeira, Manuel R. , Cheng, Timothy , Carvajal-Carmona, Luis , Shu, Xiao-Ou , Long, Jirong , Zheng, Wei , Xiang, Yong-Bing , The Australian National Endometrial Cancer Study Group (ANECS) , Montgomery, Grant W. , Webb, Penelope M. , Scott, Rodney J. , McEvoy, Mark , Lose, Felicity A. , Attia, John , Holliday, Elizabeth , Martin, Nicholas G. , Nyholt, Dale R. , Henders, Anjali K. , Fasching, Peter A. , Hein, Alexander , Beckmann, Matthias W. , Renner, Stefan P. , Dörk, Thilo , Dennis, Joe , Hillemanns, Peter , Dürst, Matthias , Runnebaum, Ingo , Lambrechts, Diether , Coenegrachts, Lieve , Schrauwen, Stefanie , Amant, Frederic , Winterhoff, Boris , Dowdy, Sean C. , Goode, Ellen L. , Michailidou, Kyriaki , Teoman, Attila , Salvesen, Helga B. , Trovik, Jone , Njolstad, Tormund S. , Werner, Henrica M. J. , Ashton, Katie , Proietto, Tony , Otton, Geoffrey , Tzortzatos, Gerasimos , Mints, Miriam , Tyrer, Jonathan P. , Tham, Emma , RENDOCAS , Hall, Per , Czene, Kamila , Liu, Jianjun , Li, Jingmei , Hopper, John L. , Southey, Melissa C. , Australian Ovarian Cancer Study (AOCS) , Ekici, Arif B. , Ahmed, Shahana , Ruebner, Matthias , Johnson, Nicola , Peto, Julian , Burwinkel, Barbara , Marme, Frederik , Brenner, Hermann , Dieffenbach, Aida K. , Miendl, Alfons , Brauch, Hiltrud , The GENICA Network, , Ferguson, Kaltin , Lindblom, Annika , Depreeuw, Jeroen , Moisse, Matthieu , Chang-Claude, Jenny , Rudolph, Anja , Couch, Fergus J. , Olsen, Janet E. , Giles, Graham G. , Bruinsma, Fiona , Cunnigham, Julie M.
- Resource Type: journal article
- Date: 2015
Meta-analysis of genome-wide association studies identifies common susceptibility polymorphisms for colorectal and endometrial cancer near SH2B3 and TSHZ1
- Creator: Cheng, Timothy H. T. , Thompson, Deborah , Hopper, John , Tomlinson, Ian , Jenkins, Mark , Lindor, Noralane M. , Newcomb, Polly A. , Gallinger, Steve , Conti, David , Schumacher, Fred , Casey, Graham , Giles, Graham G. , Pharoah, Paul , Painter, Jodie , Peto, Julian , Cox, Angela , Swerdlow, Anthony , Couch, Fergus , Cunningham, Julie M. , Goode, Ellen L. , Winham, Stacey J. , Lambrechts, Diether , Fasching, Peter , Burwinkel, Barbara , O'Mara, Tracy , Brenner, Hermann , Brauch, Hiltrud , Chang-Claude, Jenny , Salvesen, Helga B. , Kristensen, Vessela , Darabi, Hatef , Li, Jingmei , Liu, Tao , Lindblom, Annika , Hall, Per , Gorman, Maggie , de Polanco, Magdalena Echeverry , Sans, Monica , Carracedo, Angel , Castellvi-Bel, Sergi , Rojas-Martinez, Augusto , Aguiar Jnr, Samuel , Teixeira, Manuel R. , Dunning, Alison M. , Dennis, Joe , Otton, Geoffrey , Martin, Lynn , Proietto, Tony , Holliday, Elizabeth , Attia, John , Ashton, Katie , Scott, Rodney J. , McEvoy, Mark , Dowdy, Sean C. , Fridley, Brooke L. , Werner, Henrica M. J. , Trovik, Jone , Palles, Claire , Njolstad, Tormund S. , Tham, Emma , Mints, Miriam , Runnebaum, Ingo , Hillemanns, Peter , Dörk, Thilo , Amant, Frederic , Schrauwen, Stefanie , Hein, Alexander , Beckmann, Matthias W. , Jones, Angela , Ekici, Arif , Czene, Kamila , Meindl, Alfons , Bolla, Manjeet K. , Michailidou, Kyriaki , Tyrer, Jonathan P. , Wang, Qin , Ahmed, Shahana , Healey, Catherine S. , Shah, Mitul , Buchanan, Daniel D. , Annibali, Daniela , Depreeuw, Jeroen , Al-Tassan, Nada A. , Harris, Rebecca , Meyer, Brian F. , Whiffin, Nicola , Hosking, Fay J. , Kinnersley, Ben , Farrington, Susan M. , Timofeeva, Maria , Ko Win, Aung , Tenesa, Albert , Campbell, Harry , Haile, Robert W. , Hodgson, Shirley , Carvajal-Carmona, Luis , Cheadle, Jeremy P. , Easton, Douglas , Dunlop, Malcolm , Houlston, Richard , Spurdle, Amanda
- Resource Type: journal article
- Date: 2015
Prediction of breast cancer risk based on profiling with common genetic variants
- Creator: Mavaddat, Nasim , Pharoah, Paul D. P. , Michailidou, Kyriaki , Tyrer, Jonathan , Brook, Mark N. , Bolla, Manjeet K. , Wang, Qin , Dennis, Joe , Dunning, Alison M. , Shah, Mitul , Luben, Robert , Brown, Judith , Bojesen, Stig E. , Nordestgaard, Børge G. , Nielsen, Sune F. , Flyger, Henrik , Czene, Kamila , Darabi, Hatef , Eriksson, Mikael , Peto, Julian , Dos-Santos-Silva, Isabel , Dudbridge, Frank , Scott, Rodney , Yang, Rui
- Resource Type: journal article
- Date: 2015
Genetic variation in mitotic regulatory pathway genes is associated with breast tumor grade
- Creator: Purrington, Kristen S. , Slettedahl, Seth , Carpenter, Jane , Ko, Yon-Dschun , Van Deurzen, Carolien H. M. , Martens, John W. M. , Kriege, Mieke , Figueroa, Jonine D. , Chanock, Stephen J. , Lissowska, Jolanta , Tomlinson, Ian , Kerin, Michael J. , Miller, Nicola , Yannoukakos, Drakoulis , Schneeweiss, Andreas , Tapper, William J. , Gerty, Susan M. , Durcan, Lorraine , Mclean, Catriona , Milne, Roger L. , Baglietto, Laura , dos Santos Silva, Isabel , Fletcher, Olivia , Johnson, Nichola , Haiman, Christopher A. , Van'T Veer, Laura J. , Cornelissen, Sten , Försti, Ast , Torres, Diana , Rüdiger, Thomas , Rudolph, Anja , Flesch-Janys, Dieter , Nickels, Stefan , Weltens, Caroline , Floris, Giuseppe , Fasching, Peter A. , Moisse, Matthieu , Dennis, Joe , Wang, Qin , Dunning, Alison M. , Shah, Mitul , Brown, Judith , Simard, Jacques , Anton-Culver, Hoda , Neuhausen, Susan L. , Hopper, John L. , Mannermaa, Arto , Bogdanova, Natalia , Dörk, Thilo , Zheng, Wei , Radice, Paolo , Jakubowska, Anna , Lubinski, Jan , Devillee, Peter , Brauch, Hiltrud , Hooning, Maartje , García-Closas, Montserrat , Winqvist, Robert , Sawyer, Elinor , Burwinkel, Barbara , Marmee, Frederick , Eccles, Diana M. , Giles, Graham G. , Peto, Julian , Schmidt, Marjanka , Broeks, Annegien , Hamann, Ute , Chang-Claude, Jenny , Brenner, Hermann , Lambrechts, Diether , Pharoah, Paul D. P. , Easton, Douglas , Pankratz, V. Shane , Slager, Susan , Vachon, Celine M. , Couch, Fergus J. , Lindblom, Annika , Chenevix-Trench, Georgia , Benitez, Javier , Bolla, Manjeet K. , Swerdlow, Anthony , Kristensen, Vessela , Guénel, Pascal , Meindl, Alfons , Darabi, Hatef , Eriksson, Michael , Fagerholm, Rainer , Aittomäki, Kristiina , Blomqvist, Carl , Nordestgaard, Børge G. , Michailidou, Kyriaki , Nielsen, Sune F. , Flyger, Henrik , Wang, Xianshu , Olswold, Curtis , Olson, Janet E. , Mulligan, Anna Marie , Knight, Julia A. , Tchatchou, Sandrine , Reed, Malcolm W. R. , Cross, Simon S. , Czene, Kamila , Liu, Jianjun , Li, Jingmei , Humphreys, Keith , Clarke, Christine , Scott, Rodney , ABCTB Investigators , Fostira, Florentia , Fountzilas, George , Konstantopoulou, Irene , Henderson, Brian E. , Nevanlinna, Heli , Schumacher, Frederick , Le Marchand, Loic , Ekici, Arif B. , Hartmann, Arndt , Beckmann, Matthias W. , Hartikainen, Jaana M. , Kosma, Veli-Matti , Kataja, Vesa , Jukkola-Vuarinen, Arja , Pylkäs, Katri , Bojesen, Stig E. , Kauppila, Saila , Dieffenbach, Aida Karina , Stegmaier, Christa , Arndt, Volker , Margolin, Sara , Australian Ovarian Cancer Study Group , kConFab Investigators , Balleine, Rosemary , Perez, Jose Ignacio Arias , Zamora, M. Pilar , Andrulis, Irene L. , Menéndez, Primitiva , Ashworth, Alan , Jones, Michael , Orr, Nick , Arveux, Patrick , Kerbrat, Pierre , Truong, Thérèse , Bugert, Peter , Toland, Amanda E. , Ambrosone, Christine B. , Cox, Angela , Labrèche, France , Goldberg, Mark S. , Dumont, Martine , Ziogas, Argyrios , Lee, Eunjung , Dite, Gillian S. , Apicella, Carmel , Southey, Melissa C. , Long, Jirong , Shrubsole, Martha , Hall, Per , Deming-Halverson, Sandra , Ficarazzi, Fiolmena , Barile, Monica , Peterlongo, Paolo , Durda, Katarzyna , Jaworska-Bieniek, Katarzyna , Tollenaar, Robert A. E. M. , Seynaeve, Caroline , The GENICA Network , Brüning, Thomas
- Resource Type: journal article
- Date: 2014
Genome-wide association study identifies a common variant associated with risk of endometrial cancer
- Creator: Spurdle, Amanda B. , Thompson, Deborah J. , Fahey, Paul , Montgomery, Grant W. , Webb, Penelope M. , Fasching, Peter A. , Beckmann, Matthias W. , Ekici, Arif B. , Hein, Alexander , Lambrechts, Diether , Coenegrachts, Lieve , Vergote, Ignace , Ahmed, Shahana , Amant, Frederic , Salvesen, Helga B. , Trovik, Jone , Njolstad, Tormund S. , Helland, Harald , Scott, Rodney J. , Ashton, Katie , Proietto, Tony , Otton, Geoffrey , National Study of Endometrial Cancer Genetics Group, , Ferguson, Kaltin , Tomlinson, Ian , Gorman, Maggie , Howarth, Kimberley , Hodgson, Shirley , Garcia-Closas, Montserrat , Wentzensen, Nicolas , Yang, Hannah , Chanock, Stephen , Hall, Per , Czene, Kamila , Healey, Catherine S. , Liu, Jianjun , Li, Jingmei , Shu, Xiao-Ou , Zheng, Wei , Long, Jirong , Xiang, Yong-Bing , Shah, Mitul , Morrison, Jonathan , Michailidou, Kyriaki , Pharoah, Paul D. , O'Mara, Tracy , Dunning, Alison M. , Easton, Douglas F. , Walker, Logan C, , Montgomery, Stephen B. , Dermitzakis, Emmanouil T. , Australian National Endometrial Cancer Study Group,
- Resource Type: journal article
- Date: 2011