Prophylactic intranasal administration of a TLR2/6 agonist reduces upper respiratory tract viral shedding in a SARS-CoV-2 challenge ferret model
- Creator: Proud, Pamela C. , Tsitoura, Daphne , Watson, Robert J. , Chua, Brendon Y. , Aram, Marilyn J. , Bewley, Kevin R. , Cavell, Breeze E. , Cobb, Rebecca , Dowall, Stuart , Fotheringham, Susan A. , Ho, Catherine M. K. , Lucas, Vanessa , Ngabo, Didier , Rayner, Emma , Ryan, Kathryn A. , Slack, Gillian S. , Thomas, Stephen , Wand, Nadina I. , Yeates, Paul , Demaison, Christophe , Zeng, Weiguang , Holmes, Ian , Jackson, David C. , Bartlett, Nathan W. , Mercuri, Francesca , Carroll, Miles W.
- Resource Type: journal article
- Date: 2021
TLR2-mediated activation of innate responses in the upper airways confers antiviral protection of the lungs
- Creator: Deliyannis, Georgia , Wong, Chinn Yi , McQuilten, Hayley A. , Bachem, Annabell , Clarke, Michele , Jia, Xiaoxiao , Horrocks, Kylie , Zeng, Weiguang , Girkin, Jason , Scott, Nichollas E. , Londrigan, Sarah L. , Reading, Patrick C. , Bartlett, Nathan W. , Kedzierska, Katherine , Brown, Lorena E. , Mercuri, Francesca , Demaison, Christophe , Jackson, David C. , Chua, Brendon Y.
- Resource Type: journal article
- Date: 2021
TLR2-mediated innate immune priming boosts lung anti-viral immunity
- Creator: Girkin, Jason , Loo, Su-Ling , Esneau, Camille , Maltby, Steven , Mercuri, Francesca , Chua, Brendon , Reid, Andrew T. , Veerati, Punnam Chander , Grainge, Chris L. , Wark, Peter A. B. , Knight, Darryl , Jackson, David , Demaison, Christophe , Bartlett, Nathan W.
- Resource Type: journal article
- Date: 2021