A review of current therapeutics targeting the mitochondrial protease ClpP in diffuse midline glioma, H3 K27-altered
- Creator: Jackson, Evangeline R. , Persson, Mika L. , Fish, Cameron J. , Findlay, Izac J. , Mueller, Sabine , Nazarian, Javad , Hulleman, Esther , van der Lugt, Jasper , Duchatel, Ryan J. , Dun, Matthew D.
- Resource Type: journal article
- Date: 2024
Assessment of the impact of direct in vitro PFAS treatment on mouse spermatozoa.
- Creator: Calvert, Leah , Martin, Jacinta H. , Green, Mark P. , Nixon, Brett , Anderson, Amanda L. , Bernstein, Ilana R. , Burke, Nathan D. , De Iuliis, Geoffry N. , Eamens, Andrew L. , Dun, Matthew D. , Turner, Brett D. , Roman, Shaun D.
- Resource Type: journal article
- Date: 2024
Current status and advances to improving drug delivery in diffuse intrinsic pontine glioma
- Creator: Arms, Lauren M. , Duchatel, Ryan J. , Jackson, Evangeline R. , Sobrinho, Pedro Garcia , Dun, Matthew D. , Hua, Susan
- Resource Type: journal article
- Date: 2024
Diffuse midline glioma, H3K27-altered: illuminating the dark side of the moon
- Creator: Dun, Matthew D. , Odia, Yazmin , Arrillaga-Romany, Isabel
- Resource Type: journal article
- Date: 2024
Management of patients with diffuse intrinsic pontine glioma in Australia and New Zealand: Australian and New Zealand Children's Haematology/Oncology Group position statement
- Creator: Valvi, Santosh , Manoharan, Neevika , Mateos, Marion K. , Hassall, Timothy E. G. , Ziegler, David S. , McCowage, Geoffrey B. , Dun, Matthew D. , Eisenstat, David D. , Gottardo, Nicholas G. , Hansford, Jordan R.
- Resource Type: journal article
- Date: 2024
Pharmaco-phosphoproteomic analysis of cancer-associated KIT mutations D816V and V560G
- Creator: Murray, Heather C. , Miller, Kasey , Dun, Matthew D. , Verrills, Nicole M.
- Resource Type: journal article
- Date: 2024
Phosphoproteomic analysis of the adaption of epididymal epithelial cells to corticosterone challenge
- Creator: Skerrett-Byrne, David A. , Stanger, Simone J. , Dun, Matthew D. , Pang, Terence Y. , Nixon, Brett , Trigg, Natalie A. , Anderson, Amanda L. , Sipilä, Petra , Bernstein, Ilana R. , Lord, Tessa , Schjenken, John E. , Murray, Heather C. , Verrills, Nicole M.
- Resource Type: journal article
- Date: 2024
PI3K/mTOR is a therapeutically targetable genetic dependency in diffuse intrinsic pontine glioma
- Creator: Duchatel, Ryan J. , Jackson, Evangeline R. , Kearney, Padraic S. , Jamaluddin, M. Fairuz B. , Douglas, Alicia M. , Beitaki, Tyrone , McEwen, Holly P. , Persson, Mika L. , Hocke, Emily A. , Jain, Vaibhav , Aksu, Michael , Manning, Elizabeth E. , Parackal, Sarah G. , Murray, Heather C. , Verrills, Nicole M. , Hua, Susan , Cairns, Murray J. , Alvaro, Frank , Dayas, Christopher V. , Dun, Matthew D. , Hua, S , de Bock, CE , Colino-Sanguino, Y , Kiltschewskij, Dylan , Valdes-Mora, F , Tsoli, M , Ziegler, DS , Cairns, MJ , Raabe, EH , Vitanza, NA , Hulleman, E , Phoenix, TN , Koschmann, C , Alvaro, F , Findlay, Izac J. , Dayas, CV , Tinkle, CL , Wheeler, H , Whittle, JR , Eisenstat, DD , Firestein, R , Mueller, S , Valvi, S , Hansford, JR , Ashley, DM , Mannan, Abdul , Gregory, SG , Kilburn, LB , Nazarian, J , Cain, JE , Dun, MD , Staudt, Dilana E. , Thomas, Bryce C. , Germon, Zacary P. , Laternser, Sandra
- Resource Type: journal article
- Date: 2024
The oncolytic adenovirus Delta-24-RGD in combination with ONC201 induces a potent antitumor response in pediatric high-grade and diffuse midline glioma models
- Creator: de la Nava, Daniel , Ausejo-Mauleon, Iker , Tallon-Cobos, Antonio Carlos , Hernandez-Osuna, Reyes , Marco-Sanz, Javier , Dhandapani, Laasya , Hervás-Corpión, Irati , Becher, Oren J. , Nazarian, Javad , Mueller, Sabine , Phoenix, Timothy N. , van der Lugt, Jasper , Laspidea, Virginia , Hernaez, Mikel , Guruceaga, E , Koschmann, C , Venneti, S , Allen, JE , Dun, Matthew D. , Fueyo, J , Gomez-Manzano, C , Perez-Larraya, JG , Patiño-García, A , Gonzalez-Huarriz, Marisol , Labiano, S , Alonso, MM , Lacalle, Andrea , Casares, Noelia , Zalacain, Marta , Marrodan, Lucía , García-Moure, Marc , Ochoa, Maria C.
- Resource Type: journal article
- Date: 2024
Blockade of ROS production inhibits oncogenic signaling in acute myeloid leukemia and amplifies response to precision therapies
- Creator: Germon, Zacary P. , Sillar, Jonathan R. , McLachlan, Tabitha , Schjenken, John E. , Skerrett-Byrne, David A. , Huang, Honggang , Melo-Braga, Marcella N. , Plank, Maximillan W. , Alvaro, Frank , Chamberlain, Janis , De Iuliis, Geoff , Aitken, R. John , Mannan, Abdul , Nixon, Brett , Wei, AH , Enjeti, Anoop K. , Huang, Y , Lock, RB , Larsen, MR , Lee, Heather , Vaghjiani, V , Cain, JE , de Bock, CE , Duchatel, Ryan J. , Verrills, Nicole M. , Dun, Matthew D. , Staudt, Dilana , Murray, Heather C. , Findlay, Izac J. , Jackson, Evangeline R. , McEwen, Holly P. , Douglas, Alicia M.
- Resource Type: journal article
- Date: 2023
CAR T cell therapies for diffuse midline glioma
- Creator: Thomas, Bryce C. , Staudt, Dilana E. , Douglas, Alicia M. , Monje, Michelle , Vitanza, Nicholas A. , Dun, Matthew D.
- Resource Type: journal article
- Date: 2023
Clinical efficacy of ONC201 in H3K27M-mutant diffuse midline gliomas is driven by disruption of integrated metabolic and epigenetic pathways
- Creator: Venneti, Sriram , Kawakibi, Abed Rahman , Ramage, Samuel , Chi, Andrew , Wen, Patrick Y. , Arrillaga-Romany, Isabel , Batchelor, Tracy T. , Butowski, Nicholas A. , Sumrall, Ashley , Shonka, Nicole , Harrison, Rebecca A. , de Groot, John , Ji, Sunjong , Mehta, M , Hall, MD , Daghistani, D , Cloughesy, TF , Ellingson, BM , Beccaria, K , Varlet, P , Kim, MM , Umemura, Y , Garton, H , Waszak, Sebastian M. , Franson, A , Schwartz, J , Jain, R , Kachman, M , Baum, H , Burant, CF , Mottl, SL , Cartaxo, RT , John, V , Messinger, D , Sweha, StefanR , Qin, T , Peterson, E , Sajjakulnukit, P , Ravi, K , Waugh, A , Walling, D , Ding, Y , Xia, Z , Schwendeman, A , Hawes, D , Mota, Mateus , Yang, F , Judkins, AR , Wahl, D , Lyssiotis, CA , de la Nava, D , Alonso, MM , Eze, A , Spitzer, J , Schmidt, SV , Duchatel, Ryan J. , Pun, Matthew , Dun, Matthew D. , Cain, JE , Jiang, L , Stopka, SA , Baquer, G , Regan, MS , Filbin, MG , Agar, NYR , Zhao, L , Kumar-Sinha, C , Deogharkar, Akash , Mody, R , Chinnaiyan, A , Kurokawa, R , Pratt, D , Yadav, VN , Grill, J , Kline, C , Mueller, S , Resnick, A , Nazarian, J , Chung, Chan , Allen, JE , Odia, Y , Gardner, SL , Koschmann, C , Tarapore, Rohinton S.
- Resource Type: journal article
- Date: 2023
Crosstalk between DNA methylation and hypoxia in acute myeloid leukaemia
- Creator: Humphries, Sam , Bond, Danielle R. , Germon, Zacary P. , Keely, Simon , Enjeti, Anoop K. , Dun, Matthew D. , Lee, Heather J.
- Resource Type: journal article
- Date: 2023
Generation and multi-dimensional profiling of a childhood cancer cell line atlas defines new therapeutic opportunities
- Creator: Sun, Claire Xin , Daniel, Paul , Adjumain, Shazia , Sun, Christie , Chong, Wai Chin , Fernando, Dasun , Drinkwater, Caroline , Tourchi, Motahhareh , Habarakada, Dilru , Sooraj, Dhanya , Carvalho, Diana , Storm, Phillip B. , Bradshaw, Gabrielle , Baubet, Valerie , Sayles, LC , Fernandez, E , Nguyen, T , Pörksen, M , Doan, A , Crombie, DE , Panday, M , Zhukova, N , Dun, Matthew D. , Shi, Hui , Ludlow, LE , Day, B , Stringer, BW , Neeman, N , Rubens, JA , Raabe, EH , Vinci, M , Tyrrell, V , Fletcher, JI , Ekert, PG , Loi, Melissa , Dumevska, B , Ziegler, DS , Tsoli, M , Syed Sulaiman, NF , Loh, AHP , Low, SYY , Sweet-Cordero, EA , Monje, M , Resnick, A , Jones, C , Chew, Nicole , Downie, P , Williams, B , Rosenbluh, J , Gough, D , Cain, JE , Firestein, R , Parackal, Sarah , Tsui, Vanessa , Liang, Yuqing , Koptyra, Mateusz
- Resource Type: journal article
- Date: 2023
Synergistic Targeting of DNA-PK and KIT Signaling Pathways in KIT Mutant Acute Myeloid Leukemia
- Creator: Murray, Heather C. , Miller, Kasey , Brzozowski, Joshua S. , Kahl, Richard G. S. , Smith, Nathan D. , Humphrey, Sean J. , Dun, Matthew D. , Verrills, Nicole M.
- Resource Type: journal article
- Date: 2023
Therapeutic HDAC inhibition in hypermutant diffuse intrinsic pontine glioma.
- Creator: Noll, Alyssa , Myers, Carrie , Winter, Conrad , Pakiam, Fiona , Leary, Sarah E. S. , Cole, Bonnie L. , Jackson, Evangeline R. , Dun, Matthew D. , Foster, Jessica B. , Evans, Myron K. , Pattwell, Siobhan S. , Olson, James M. , Biery, Matthew C. , Vitanza, Nicholas A. , Meechan, Michael , Tahiri, Sophie , Rajendran, Asmitha , Berens, Michael E. , Paine, Danyelle , Byron, Sara , Zhang, Jiaming
- Resource Type: journal article
- Date: 2023
Therapeutic targeting of prenatal pontine ID1 signaling in diffuse midline glioma
- Creator: Messinger, Dana , Harris, Micah K. , Qin, Tingting , Mullan, Brendan , Siada, Ruby , Ravindran, Ramya , Niculcea, Michael , Dowling, Abigail R. , Bradin, Joshua , Ginn, Kevin F. , Gener, Melissa A. H. , Dorris, Kathleen , Cummings, Jessica R. , Vitanza, Nicholas A. , Schmidt, SV , Spitzer, J , Li, J , Filbin, MG , Cao, X , Castro, MG , Lowenstein, PR , Mody, R , Chinnaiyan, A , Thomas, Chase , Desprez, PY , McAllister, S , Dun, Matthew D. , Hawkins, C , Waszak, SM , Venneti, S , Koschmann, C , Yadav, VN , Yang, Tao , Sweha, Stefan R. , Woo, Rinette , Siddaway, Robert , Burkert, Martin , Stallard, Stefanie
- Resource Type: journal article
- Date: 2023
Translational considerations for immunotherapy clinical trials in pediatric neuro-oncology
- Creator: Foster, Jessica B. , Alonso, Marta M. , Sayour, Elias , Davidson, Tom B. , Persson, Mika L. , Dun, Matthew D. , Kline, Cassie , Mueller, Sabine , Vitanza, Nicholas A. , van der Lugt, Jasper
- Resource Type: journal article
- Date: 2023
Assessment of the Emerging Threat Posed by Perfluoroalkyl and Polyfluoroalkyl Substances to Male Reproduction in Humans
- Creator: Calvert, Leah , Green, Mark P. , De Iuliis, Geoffry N. , Dun, Matthew D. , Turner, Brett D. , Clarke, Bradley O. , Eamens, Andrew L. , Roman, Shaun D. , Nixon, Brett
- Resource Type: journal article
- Date: 2022
B-cell Lymphoma 6 (BCL6): From Master Regulator of Humoral Immunity to Oncogenic Driver in Pediatric Cancers
- Creator: McLachlan, Tabitha , Matthews, William C. , Dun, Matthew D. , Jackson, Evangeline R. , Staudt, Dilana E. , Douglas, Alicia M. , Findlay, Izac J. , Persson, Mika L. , Duchatel, Ryan J. , Mannan, Abdul , Germon, Zacary P.
- Resource Type: journal article
- Date: 2022