Multi-phenotype analyses of hemostatic traits with cardiovascular events reveal novel genetic associations
- Creator: Temprano-Sagrera, Gerard , Sitlani, Colleen M. , Dehghan, Abbas , Heath, Adam S. , Reiner, Alex P. , Johnson, Andrew , Richmond, Anne , Peters, Annette , van Hylckama Vlieg, Astrid , McKnight, Barbara , Psaty, Bruce M. , Hayward, Caroline , Bone, William P. , Holliday, Elizabeth G. , Attia, John , Levi, Christopher R. , Chasman, D , Strachan, DP , Tregouet, DA , Mook-Kanamori, D , Gill, D , Thibord, F , Asselbergs, FW , Martin-Bornez, Miguel , Leebeek, FWG , Rosendaal, FR , Davies, G , Homuth, G , Temprano, G , Campbell, H , Taylor, HA , Bressler, J , Huffman, JE , Rotter, JI , Voight, Benjamin F. , Yao, J , Wilson, JF , Bis, JC , Hahn, JM , Desch, KC , Wiggins, KL , Raffield, LM , Bielak, LF , Yanek, LR , Kleber, ME , Morrison, Alanna C. , Sabater-Lleal, M , Mueller, M , Kavousi, M , Mangino, M , Liu, M , Brown, MR , Conomos, MP , Jhun, MA , Chen, MH , de Maat, MPM , Damrauer, Scott M. , Pankratz, N , Peyser, PA , Elliot, P , Wei, P , Wild, PS , Morange, PE , van der Harst, P , Yang, Q , Le, NQ , Marioni, R , de Vries, Paul S. , Li, R , Damrauer, SM , Cox, SR , Trompet, S , Felix, SB , Völker, U , Tang, W , Koenig, W , Jukema, JW , Guo, X , Smith, Nicholas L. , Lindstrom, S , Wang, L , Smith, EN , Gordon, W , van Hylckama Vlieg, A , de Andrade, M , Brody, JA , Pattee, JW , Haessler, J , Brumpton, BM , Sabater-Lleal, Maria , Chasman, DI , Suchon, P , Turman, C , Germain, M , MacDonald, J , Braekkan, SK , Armasu, SM
- Resource Type: journal article
- Date: 2022
1000 genomes-based meta-analysis identifies 10 novel loci for kidney function
- Creator: Gorski, Mathias , van der Most, Peter J. , Li, Yong , Sedaghat, S , Smith, AV , Sorice, R , Stengel, B , Stracke, S , Strauch, K , Toniolo, D , Uitterlinden, AG , Ulivi, S , Viikari, JS , Tayo, Bamidele , Voelker, U , Vollenweider, P , Voelzke, H , Vuckovic, D , Waldenberger, M , Wang, JJ , Yang, Q , Chasman, DI , Tromp, G , Snieder, H , Tin, Adrienne , Heid, IM , Fox, CS , Koettgen, A , Pattaro, C , Boeger, CA , Fuchsberger, C , Feitosa, Mary F. , Aspelund, Thor , Attia, John , Biffar, Reiner , Bochud, Murielle , Boerwinkle, Eric , Borecki, Ingrid , Teumer, Alexander , Bottinger, Erwin P. , Chen, Ming-Huei , Chouraki, Vincent , Ciullo, Marina , Coresh, Josef , Cornelis, Marilyn C. , Curhan, Gary C. , d'Adamo, Adamo P. , Dehghan, Abbas , Dengler, Laura , Chu, Audrey Y. , Ding, Jingzhong , Eiriksdottir, Gudny , Endlich, K , Enroth, S , Esko, T , Franco, OH , Gasparini, P , Gieger, C , Girotto, G , Gottesman, O , Li, Man , Gudnason, V , Gyllensten, U , Hancock, Stephen J. , Harris, TB , Helmer, C , Hoellerer, S , Hofer, E , Hofman, A , Holliday, Elizabeth , Homuth, G , Mijatovic, Vladan , Hu, FB , Huth, C , Hutri-Kahonen, N , Hwang, S-J , Imboden, M , Johansson, A , Kahonen, M , Koenig, W , Kraemer, H , Kramer, BK , Nolte, Ilja M. , Kumar, A , Kutalik, Z , Lambert, J-C , Launer, LJ , Lehtimaki, T , de Borst, M , Navis, G , Swertz, M , Liu, Y , Lohman, K , Cocca, Massimiliano , Loos, RJF , Lu, Y , Lyytikainen, L-P , McEvoy, Mark A. , Meisinger, C , Meitinger, T , Metspalu, A , Metzger, M , Mihailov, E , Mitchell, P , Taliun, Daniel , Nauck, M , Oldehinkel, AJ , Olden, M , Penninx, BWJH , Pistis, G , Pramstaller, PP , Probst-Hensch, N , Raitakari, OT , Rettig, R , Ridker, PM , Gomez, Felicia , Rivadeneira, F , Robino, A , Rosas, SE , Ruderfer, D , Ruggiero, D , Saba, Y. , Sala, C. , Schmidt, H , Schmidt, R , Scott, Rodney J.
- Resource Type: journal article
- Date: 2017
Comparison of HapMap and 1000 genomes reference panels in a large-scale genome-wide association study
- Creator: de Vries, Paul S. , Sabater-Lleal, Maria , Marioni, Riccardo E. , Steri, Maristella , Weng, Lu-Chen , Pool, Rene , Grossmann, Vera , Brody, Jennifer A. , Venturini, Cristina , Tanaka, Toshiko , Rose, Lynda M. , Oldmeadow, Christopher , Chasman, Daniel I. , Mazur, Johanna , Basu, Saonli , Frånberg, Mattias , Yang, Qiong , Ligthart, Symen , Hottenga, Jouke J. , Rumley, Ann , Mulas, Antonella , de Craen, Anton J. M. , Grotevendt, Anne , Trompet, Stella , Taylor, Kent D. , Delgado, Graciela E. , Kifley, Annette , Lopez, Lorna M. , Berentzen, Tina L. , Mangino, Massimo , Bandinelli, Stefania , Morrison, Alanna C. , Hamsten, Anders , Tofler, Geoffrey , Ahluwalia, Tarunveer S. , de Maat, Moniek P. M. , Draisma, Harmen H. M. , Lowe, Gordon D. , Zoledziewska, Magdalena , Sattar, Naveed , Lackner, Karl J. , Völker, Uwe , McKnight, Barbara , Huang, Jie , Holliday, Elizabeth G. , Teumer, Alexander , McEvoy, Mark A. , Starr, John M. , Hysi, Pirro G. , Hernandez, Dena G. , Guan, Weihua , Rivadeneira, Fernando , McArdle, Wendy L. , Slagboom, P. Eline , Zeller, Tanja , Psaty, Bruce M. , Kleber, Marcus E. , Uitterlinden, André G. , de Geus, Eco J. C. , Stott, David J. , Binder, Harald , Hofman, Albert , Franco, Oscar H. , Rotter, Jerome I. , Ferrucci, Luigi , Spector, Tim D. , Deary, Ian J. , Chen, Ming-Huei , März, Winfried , Greinacher, Andreas , Wild, Philipp S. , Cucca, Francesco , Boomsma, Dorret I. , Watkins, Hugh , Tang, Weihong , Ridker, Paul M. , Jukema, Jan W. , Scott, Rodney J. , Wang, Jie Jin , Mitchell, Paul , Hansen, Torben , O'Donnell, Christopher J. , Smith, Nicholas L. , Strachan, David P. , Dehghan, Abbas , Attia, John R.
- Resource Type: journal article
- Date: 2017
Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function
- Creator: Pattaro, Cristian , Teumer, Alexander , Taliun, Daniel , Wallaschofski, Henri , Vöelzke, Henry , Brenner, Hermann , Kroemer, Heyo K. , Kramer, Holly , Lin, Honghuang , Leach, I. Mateo , Ford, Ian , Guessous, Idris , Rudan, Igor , Olden, Matthias , Prokopenko, Inga , Borecki, Ingrid , Heid, Iris M. , Kolcic, Ivana , Persico, Ivana , Jukema, J. Wouter , Wilson, James F. , Felix, Janine F. , Divers, Jasmin , Lambert, Jean-Charles , Foster, Meredith , Stafford, Jeanette M. , Gaspoz, Jean-Michel , Smith, Jennifer A. , Faul, Jessica D. , Wang, Jie Jin , Ding, Jingzhong , Hirschhorn, Joel N. , Attia, John , Whitfield, John B. , Chalmers, John , Yang, Qiong , Viikari, Jorma , Coresh, Josef , Denny, Joshua C. , Karjalainen, Juha , Fernandes, Jyotika K. , Endlich, Karlhans , Butterbach, Katja , Keene, Keith L. , Lohman, Kurt , Portas, Laura , Chen, Ming-Huei , Launer, Lenore J. , Lyytikäinen, Leo-Pekka , Yengo, Loic , Franke, Lude , Ferrucci, Luigi , Rose, Lynda M. , Kedenko, Lyudmyla , Rao, Madhumathi , Struchalin, Maksim , Kleber, Marcus E. , Pers, Tune H. , Cavalieri, Margherita , Haun, Margot , Cornelis, Marilyn C. , Ciullo, Marina , Pirastu, Mario , de Andrade, Mariza , McEvoy, Mark A. , Woodward, Mark , Adam, Martin , Cocca, Massimiliano , Johnson, Andrew D. , Nauck, Matthias , Imboden, Medea , Waldenberger, Melanie , Pruijm, Menno , Metzger, Marie , Stumvoll, Michael , Evans, Michele K. , Sale, Michele M. , Käehöenen, Mika , Boban, Mladen , Ko, Yi-An , Bochud, Murielle , Rheinberger, Myriam , Verweij, Niek , Bouatia-Naji, Nabila , Martin, Nicholas G. , Hastie, Nick , Probst-Hensch, Nicole , Soranzo, Nicole , Devuyst, Olivier , Raitakari, Olli , Fuchsberger, Christian , Gottesman, Omri , Franco, Oscar H. , Polasek, Ozren , Gasparini, Paolo , Munroe, Patricia B. , Ridker, Paul M. , Mitchell, Paul , Muntner, Paul , Meisinger, Christa , Smit, Johannes H. , Tayo, Bamidele , Kovacs, Peter , Wild, Philipp S. , Froguel, Philippe , Rettig, Rainer , Mäegi, Reedik , Biffar, Reiner , Schmidt, Reinhold , Middelberg, Rita P. S. , Carroll, Robert J. , Penninx, Brenda W. , Gorski, Mathias , Nalls, Michael , Scott, Rodney J. , Katz, Ronit , Sedaghat, Sanaz , Wild, Sarah H. , Kardia, Sharon L. R. , Ulivi, Sheila , Hwang, Shih-Jen , Enroth, Stefan , Kloiber, Stefan , Trompet, Stella , Feitosa, Mary F. , Stengel, Benedicte , Hancock, Stephen J. , Turner, Stephen T. , Rosas, Sylvia E. , Stracke, Sylvia , Harris, Tamara B. , Zeller, Tanja , Zemunik, Tatijana , Lehtimäki, Terho , Illig, Thomas , Isaacs, Aaron , Aspelund, Thor , Nikopensius, Tiit , Esko, Tonu , Tanaka, Toshiko , Gyllensten, Ulf , Völker, Uwe , Emilsson, Valur , Vitart, Veronique , Aalto, Ville , Gudnason, Vilmundur , Dehghan, Abbas , Chouraki, Vincent , Chen, Wei-Min , Igl, Wilmar , März, Winfried , Koenig, Wolfgang , Lieb, Wolfgang , Loos, Ruth J. F. , Liu, Yongmei , Snieder, Harold , Pramstaller, Peter P. , d'Adamo, Pio , Parsa, Afshin , O'Connell, Jeffrey R. , Susztak, Katalin , Hamet, Pavel , Tremblay, Johanne , de Boer, Ian H. , Böger, Carsten A. , Goessling, Wolfram , Chasman, Daniel I. , Köttgen, Anna , Adeyemo, Adebowale , Kao, W. H. Linda , Fox, Caroline S. , ICBP Consortium , AGEN Consortium , CARDIOGRAM , CHARGe-Heart Failure Group , ECHOGen Consortium , Dieffenbach, Aida Karina , Zonderman, Alan B. , Nolte, Ilja M. , van der Most, Peter J. , Chu, Audrey Y. , Wright, Alan F. , Shuldiner, Alan R. , Morrison, Alanna C. , Hofman, Albert , Smith, Albert V. , Dreisbach, Albert W. , Franke, Andre , Uitterlinden, Andre G. , Metspalu, Andres , Tonjes, Anke , Li, Man , Lupo, Antonio , Robino, Antonietta , Johansson, Åsa , Demirkan, Ayse , Kollerits, Barbara , Freedman, Barry I. , Ponte, Belen , Oostra, Ben A. , Paulweber, Bernhard , Kräemer, Bernhard K. , Mijatovic, Vladan , Mitchell, Braxton D. , Buckley, Brendan M. , Peralta, Carmen A. , Hayward, Caroline , Helmer, Catherine , Rotimi, Charles N. , Shaffer, Christian M. , Müeller, Christian , Sala, Cinzia , van Duijn, Cornelia M. , Garnaas, Maija , Saint-Pierre, Aude , Ackermann, Daniel , Shriner, Daniel , Ruggiero, Daniela , Toniolo, Daniela , Lu, Yingchang , Cusi, Daniele , Czamara, Darina , Ellinghaus, David , Siscovick, David S. , Tin, Adrienne , Ruderfer, Douglas , Gieger, Christian , Grallert, Harald , Rochtchina, Elena , Atkinson, Elizabeth J. , Holliday, Elizabeth G. , Boerwinkle, Eric , Salvi, Erika , Bottinger, Erwin P. , Murgia, Federico , Sorice, Rossella , Rivadeneira, Fernando , Ernst, Florian , Kronenberg, Florian , Hu, Frank B. , Navis, Gerjan J. , Curhan, Gary C. , Ehret, George B. , Homuth, Georg , Coassin, Stefan , Thun, Gian-Andri , Li, Yong , Pistis, Giorgio , Gambaro, Giovanni , Malerba, Giovanni , Montgomery, Grant W. , Eiriksdottir, Gudny , Jacobs, Gunnar , Li, Guo , Wichmann, H-Erich , Campbell, Harry , Schmidt, Helena
- Resource Type: journal article
- Date: 2016
Investigating the causal relationship of C-reactive protein with 32 complex somatic and psychiatric outcomes: a large-scale cross-consortium mendelian randomization study
- Creator: Prins, Bram P. , Abbasi, Ali , Valdes, Ana M. , Bras, Jose , Shatunov, Aleksey , Lu, Chen , Han, Buhm , Raychaudhuri, Soumya , Bevan, Steve , Mayes, Maureen D. , Tsoi, Lam C. , Evangelou, Evangelos , Wong, Anson , Nair, Rajan P. , Grant, Stuan F. A. , Polychronakos, Constantin , Radstake, Timothy R. D. , van Heel, David A. , Dunstan, Melanie L. , Wood, Nicholas W. , Al-Chalabi, Ammar , Dehghan, Abbas , Hakonarson, Hakon , Vaez, Ahmad , Markus, Hugh S. , Elder, James T. , Knight, Jo , Arking, Dan E. , Spector, Timothy D. , Koeleman, Bobby P. C. , van Duijn, Cornelia M. , Martin, Javier , Morris, Andrew P. , Weersma, Rinse K. , Nolte, Ilja , Wijmenga, Cisca , Munroe, Patricia B. , Perry, John R. B. , Pouget, Jennie G. , Jamshidi, Yalda , Snieder, Harold , Alizadeh, Behrooz Z. , Tooney, Paul , Franceschini, Nora , Stuart, Philip E. , Guterriez Achury, Javier , Mistry, Vanisha , Bradfield, Jonathan P.
- Resource Type: journal article
- Date: 2016
Maternal plasma folate impacts differential DNA methylation in an epigenome-wide meta-analysis of newborns
- Creator: Joubert, Bonnie R. , den Dekker, Herman T. , Håberg, Siri E. , Reese, Sarah E. , Peters, Marjolein J. , Kulle Andreassen, Bettina , Steegers, Eric A. P. , Nilsen, Roy M. , Vollset, Stein E. , Midttun, Øivind , Ueland, Per M. , Franco, Oscar H. , Felix, Janine F. , Dehghan, Abbas , de Jongste, Johan C. , Wu, Michael C. , Wang, Tianyuan , Peddada, Shyamal D. , Jaddoe, Vincent W. V. , Nystad, Wenche , Duijts, Liesbeth , London, Stephanie J. , Bohlin, Jon , Ligthart, Symen , Beckett, Emma , Tiemeier, Henning , van Meurs, Joyce B. , Uitterlinden, Andre G. , Hofman, Albert
- Resource Type: journal article
- Date: 2016
Genome-wide association study of kidney function decline in individuals of European descent.
- Creator: Gorski, Mathias , Tin, Adreienne , Hamet, Pavel , Köttgen, Anna , Kao, W. H. , Fox, Caroline S. , Böger, Carsten A. , Tremblay, Johanne , Woodward, Marc , Aspelund, Thor , Eiriksdottir, Gudney , Gudnason, Vilmundur , Harris, Tamara B, , Launer, Lenore J. , Smith, Albert V. , Mitchell, Braxton D. , Garnaas, Maija , O'Connell, Jeffrey R. , Shuldiner, Alan R. , Coresh, Josef , Li, Man , Freudenberger, Paul , Hofer, Edith , Schmidt, Helena , Schmidt, Reinhold , Holliday, Elizabeth G. , Mitchell, Paul , McMahon, Gearoid M. , Wang, Jie Jin , de Boer, Ian H, , Li, Guo , Siscovick, David S. , Kutalik, Zoltan , Corre, Tanguy , Vollenweider, Peter , Waeber, Gerard , Gupta, Jayanta , Kanetsky, Peter A, , Chu, Audrey Y, , Hwang, Shih-Jen , Olden, Matthias , Yang, Qiong , de Andrade, Mariza , Atkinson, Elizabeth J. , Kardia, Sharon L. R. , Turner, Stephen T, , Stafford, Jeanette M. , Ding, Jingzhong , Liu, Yongmei , Tayo, Bamidele O. , Barlassina, Cristina , Cusi, Daniele , Salvi, Erika , Staessen, Jan A. , Ridker, Paul M. , Grallert, Harald , Meisinger, Christa , Müller-Nurasyid, Martina , Krämer, Bernhard K. , Kramer, Holly , Pattaro, Cristian , Rosas, Sylvia E. , Nolte, Ilja M. , Penninx, Brenda W. , Snieder, Harold , Fabiola Del Greco, M. , Franke, Andre , Nöthlings, Ute , Lieb, Wolfgang , Bakker, Stehan J. L. , Gansevoort, Ron T. , Teumer, Alexander , van der Harst, Pim , Dehghan, Abbas , Franco, Oscar H. , Hofman, Albert , Rivadeneira, Fernando , Sedaghat, Sanaz , Uitterlinden, Andre G. , Coassin, Stefan , Haun, Margot , Kollerits, Barbara , Chasman, Daniel I. , Kronenberg, Florian , Paulweber, Bernhard , Aumann, Nicole , Endlich, Karlhans , Pietzner, Mike , Völker, Uwe , Rettig, Rainer , Chouraki, Vincent , Helmer, Catherine , Lambert, Jean-Charles , Chalmers, John , Metzger, Marie , Stengel, Benedicte , Lehtimäki, Terho , Lyytikäinen, Leo-Pekka , Raitakari, Olli , Johnson, Andrew , Parsa, Afshin , Bochud, Murielle , Heid, Iris M. , Goessling, Wolfram
- Resource Type: journal article
- Date: 2014
Genome-wide association and functional follow-up reveals new loci for kidney function
- Creator: Pattaro, Cristian , Kottgen, Anna , Li, Man , Uitterlinden, Andre G. , Rivadeneira, Fernando , Aulchenko, Yurii S. , Polasek, Ozren , Hastie, Nick , Vitart, Veronique , Helmer, Catherine , Wang, Jie Jin , Ruggiero, Daniela , Bergmann, Sven , Gao, Xiaoyi , Kahonen, Mika , Viikari, Jorma , Nikopensius, Tiit , Province, Michael , Ketkar, Shamika , Colhoun, Helen , Doney, Alex , Robino, Antonietta , Giulianini, Franco , Kramer, Bernhard K. , Gorski, Mathias , Portas, Laura , Ford, Ian , Buckley, Brendan M. , Adam, Martin , Thun, Gian-Andri , Paulweber, Bernhard , Haun, Margot , Sala, Cinzia , Metzger, Marie , Mitchell, Paul , Yang, Qiong , Ciullo, Marina , King, Stuart K. , Vollenweider, Peter , Raitakari, Olli , Metspalu, Andres , Palmer, Colin , Gasparini, Paolo , Pirastu, Mario , Jukema, J. Wouter , Probst-Hensch, Nicole M. , Hundertmark, Claudia , Kronenberg, Florian , Toniolo, Daniela , Gudnason, Vilmundur , Shuldiner, Alan R. , Coresh, Josef , Schmidt, Reinhold , Ferrucci, Luigi , Siscovick, David S. , van Duijn, Cornelia M. , Borecki, Ingrid , Foster, Meredith C. , Kardia, Sharon L. R. , Liu, Yongmei , Curhan, Gary C. , Rudan, Igor , Gyllensten, Ulf , Wilson, James F. , Franke, Andre , Pramstaller, Peter P. , Retting, Rainer , Prokopenko, Inga , O'Seaghdha, Conall M. , Witteman, Jacqueline C. M. , Hayward, Caroline , Ridker, Paul , Parsa, Afshin , Bochud, Murielle , Heid, Iris M. , Goessling, Wolfram , Chasman, Daniel I. , Kao, W. H. Linda , Fox, Caroline S. , Glazer, Nicole , Isaacs, Aaron , Liu, Ching-Ti , Teumer, Alexander , Smith, Albert V. , O'Connell, Jeffrey R. , Struchalin, Maksim , Tanaka, Toshiko , Li, Guo , Johnson, Andrew D. , Gierman, Hinco J. , Feitosa, Mary , Hwang, Shih-Jen , Atkinson, Elizabeth J. , Garnaas, Maija , Lohman, Kurt , Cornelis, Marilyn C. , Johansson, Asa , Tonjes, Anke , Dehghan, Abbas , Chouraki, Vincent , Holliday, Elizabeth G. , Sorice, Rossella , Kutalik, Zoltan , Lehtimaki, Terho , Boger, Carsten A. , Esko, Tonu , Deshmukh, Harshal , Ulivi, Sheila , Chu, Audrey Y. , Murgia, Federico , Trompet, Stella , Imboden, Medea , Kollerits, Barbara , Pistis, Giorgio , CARDIoGRAM Consortium , Fuchsberger, Christian , ICBP Consortium , CARe Consortium , Wellcome Trust Case Control Consortium 2 (WTCCC2) , Harris, Tamara B. , Launer, Lenore J. , Aspelund, Thor , Eiriksdottir, Gudny , Mitchell, Braxton D. , Boerwinkle, Eric , Schmidt, Helena , Olden, Matthias , Cavalieri, Margherita , Rao, Madhumathi , Hu, Frank B. , Demirkan, Ayse , Oostra, Ben A. , de Andrade, Mariza , Turner, Stephen T. , Ding, Jingzhong , Andrews, Jeanette S. , Freedma, Barry I. , Chen, Ming-Huei , Koenig, Wolfgang , Illig, Thomas , Doring, Angela , Wichmann, H.-Erich , Kolcic, Ivana , Zemunik, Tatijana , Boban, Mladen , Minelli, Cosetta , Wheeler, Heather E. , Igl, Wilmar , Tin, Adrienne , Zaboli, Ghazal , Wild, Sarah H. , Wright, Alan F. , Campbell, Harry , Ellinghaus, David , Nothlings, Ute , Jacobs, Gunnar , Biffar, Reiner , Endlich, Karlhans , Ernst, Florian , Taliun, Daniel , Homuth, Georg , Kroemer, Heyo K. , Nauck, Matthias , Stracke, Sylvia , Volker, Uwe , Volzke, Henry , Kovacs, Peter , Stumvoll, Michael , Magi, Reedik , Hofman, Albert
- Resource Type: journal article
- Date: 2012