- Title
- Correlation of 3D-planned and measured dosimetry of photon and electron craniospinal radiation in a pediatric anthropomorphic phantom
- Creator
- Hood, Claire; Kron, Tomas; Hamilton, Chris; Callan, Scott; Howlett, Steve; Alvaro, F.; Back, M.
- Relation
- Radiotherapy and Oncology Vol. 77, no. 1, p. 111-116
- Publisher
- Elsevier
- Resource Type
- journal article
- Date
- 2005
- Description
- Background and Purpose: Improved radiotherapy techniques in pediatric craniospinal therapy (CSRT) strive to reduce risks of late morbidity. Using a pediatric anthropomorphic phantom, this research correlated measured target and normal tissue dose to that predicted from a 3D planning system (3D-RTP). Patients and Methods: A pediatric anthropomorphic phantom was planned following French Society of Pediatric Oncology (SFOP) protocols. Thermoluminescent detectors (TLDs) were used to perform dosimetric measurements during treatment. 4 and 6 MV photon fields with multi leaf collimation (MLC) or custom blocks were compared to 3D-RTP computer (ADAC Pinnacle) predictions for cranial fields. Spinal dosimetry was studied using photons (4 and 6 MV) and electrons (9 and 12 MeV). Results: 3D-RTP predictions generally concurred with dose received in cranial and spinal sites. The measured dose was over-predicted significantly by the 3D-RTP in the anterior cranial fossa. Normal tissue doses were reduced when treating the spine using megavoltage electron beams instead of photons. Conclusions: Treating the spinal field with electrons minimises the risk of pulmonary sequelae, however electron energy selection is critical to achieve adequate spinal field coverage. Despite adhering to a major trial protocol guideline, dose at the floor of the anterior cranial fossa remains a potential clinical problem and 3D-RTP do not predict this well. © 2005 Elsevier Ireland Ltd. All rights reserved.
- Subject
- Craniospinal; Dosimetry; Electron beam; Medulloblastoma; Radiotherapy
- Identifier
- http://hdl.handle.net/1959.13/25127
- Identifier
- uon:275
- Identifier
- ISSN:0167-8140
- Language
- eng
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