- Title
- Diet and COPD: A Gut Feeling About Pathogenesis
- Creator
- Dowling, Laura R. C.; Scott, Hayley A.
- Relation
- Chronic Obstructive Pulmonary Disease: Journal of the COPD Foundation Vol. 11, Issue 2, p. 133-135
- Publisher Link
- http://dx.doi.org/10.15326/jcopdf.2024.0508
- Publisher
- C O P D Foundation
- Resource Type
- journal article
- Date
- 2024
- Description
- Chronic obstructive pulmonary disease (COPD) is one of the leading causes of morbidity and mortality worldwide. Consequently, there is an urgent need to determine modifiable risk factors that contribute to both its development and progression. Dietary intake is being increasingly recognized as a potential modifiable risk factor for COPD, as research indicates it has a key role in the development of a wide range of other chronic health conditions including cardiovascular disease, type 2 diabetes, and metabolic syndrome.1-3 However, research investigating the impact of diet on lung disease is extremely limited. Fruits and vegetables are one dietary component that may reduce the risk of lung disease, as they are high in antioxidants such as anthocyanins, beta-carotene, and lycopene, which have been identified to play a role in reducing oxidative stress and protecting against oxidant-mediated inflammation.4 Fruits and vegetables are also a major source of dietary fiber, which is known to modulate the gut microbiome.5 Both the gut microbiome and bacterial metabolites produced in the gut are recognized for their involvement in immune signaling and have been shown to have a role in the progression of other airway diseases, including asthma.6
- Subject
- Chronic obstructive pulmonary disease (COPD); plant-based diet; gut microbiota; A Priori Diet Quality Score
- Identifier
- http://hdl.handle.net/1959.13/1501450
- Identifier
- uon:55139
- Identifier
- ISSN:2372-952X
- Language
- eng
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