- Title
- Modelling Genetic Benefits and Financial Costs of Integrating Biobanking into the Captive Management of Koalas
- Creator
- Howell, Lachlan G.; Johnston, Stephen D.; O'Brien, Justine K.; Frankham, Richard; Rodger, John C.; Ryan, Shelby A.; Beranek, Chad T.; Clulow, John; Hudson, Donald. S.; Witt, Ryan R.
- Relation
- Animals Vol. 12, Issue 8, no. 990
- Publisher Link
- http://dx.doi.org/10.3390/ani12080990
- Publisher
- MDPI AG
- Resource Type
- journal article
- Date
- 2022
- Description
- Zoo and wildlife hospital networks are set to become a vital component of Australia’s contemporary efforts to conserve the iconic and imperiled koala (Phascolarctos cinereus). Managed breeding programs held across zoo-based networks typically face high economic costs and can be at risk of adverse genetic effects typical of unavoidably small captive colonies. Emerging evidence suggests that biobanking and associated assisted reproductive technologies could address these economic and genetic challenges. We present a modelled scenario, supported by detailed costings, where these technologies are optimized and could be integrated into conservation breeding programs of koalas across the established zoo and wildlife hospital network. Genetic and economic modelling comparing closed captive koala populations suggest that supplementing them with cryopreserved founder sperm using artificial insemination or intracytoplasmic sperm injection could substantially reduce inbreeding, lower the required colony sizes of conservation breeding programs, and greatly reduce program costs. Ambitious genetic retention targets (maintaining 90%, 95% and 99% of source population heterozygosity for 100 years) could be possible within realistic cost frameworks, with output koalas suited for wild release. Integrating biobanking into the zoo and wildlife hospital network presents a cost-effective and financially feasible model for the uptake of these tools due to the technical and research expertise, captive koala colonies, and ex situ facilities that already exist across these networks.
- Subject
- assisted reproductive technologies; artifical reproductive technologies; biobanking; captive breeding; genetirc diversity; genome resource banking
- Identifier
- http://hdl.handle.net/1959.13/1487481
- Identifier
- uon:52161
- Identifier
- ISSN:2076-2615
- Rights
- © 2022 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
- Language
- eng
- Full Text
- Reviewed
- Hits: 1386
- Visitors: 1457
- Downloads: 80
| Thumbnail | File | Description | Size | Format | |||
|---|---|---|---|---|---|---|---|
| View Details Download | ATTACHMENT02 | Publisher version (open access) | 700 KB | Adobe Acrobat PDF | View Details Download |