- Title
- The therapeutic potential of the labdane diterpenoid forskolin
- Creator
- Salehi, Bahare; Staniak, Mariola; Czopek, Katarzyna; Stepien, Anna; Dua, Kamal; Wadhwa, Ridhima; Chellappan, Dinesh Kumar; Sytar, Oksana; Brestic, Marian; Bhat, Namrata Ganesh; Kumar, Nanjangud Venkatesh Anil; Contreras, Maria del Mar; Sharopov, Farukh; Cho, William C.; Sharifi-Rad, Javad
- Relation
- Applied Sciences Vol. 9, Issue 19, no. 4089
- Publisher Link
- http://dx.doi.org/10.3390/app9194089
- Publisher
- MDPI AG
- Resource Type
- journal article
- Date
- 2019
- Description
- Forskolin is mainly found in the root of a plant called Coleus forskohlii (Willd.) Briq., which has been used in the traditional medicine of Indian Ayurvedic and Southeast Asia since ancient times. Forskolin is responsible for the pharmacological activity of this species. Forskolin is a labdane diterpenoid with a wide biological effect. Several studies suggested a positive role of forskolin on heart complications, respiratory disorders, high blood pressure, obesity, and asthma. There are numerous clinical and pre-clinical studies representing the effect of forskolin on the above-mentioned disorders but more clinical studies need to be performed to support its efficacy.
- Subject
- forskolin; plant secondary metabolites; Coleus forskohlii; cAMP pathway; SDG 3; Sustainable Development Goals
- Identifier
- http://hdl.handle.net/1959.13/1445404
- Identifier
- uon:42579
- Identifier
- ISSN:2076-3417
- Language
- eng
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