- Title
- Regulating RNA research and CRISPR gene drives to combat biosecurity threats
- Creator
- Faunce, Thomas; Ray, Andrew; Gardiner, Christie; Preiss, Thomas; Burgio, Gaetan
- Relation
- Journal of Law and Medicine Vol. 26, Issue 1, p. 208-213
- Relation
- https://pubmed.ncbi.nlm.nih.gov/30302983
- Publisher
- Lawbook Co.
- Resource Type
- journal article
- Date
- 2018
- Description
- Recent technological breakthroughs in ribonucleic acid (RNA) research and the creation of synthetic gene drives using CRISPR/Cas9 have increased attention on the ethical and legal regulation of this field. RNA is now perceived as not merely a passive carrier of DNA information but especially through its propensity to mutate as a computation engine of cell biology, developmental biology and evolution. Synthetic Gene drives have been hailed as a potential strategy to reduce climate-change-mediated biosecurity threats such as spreading malaria and have attracted significant investment, with the Gates Foundation pledging US$75 million and the Defense Advanced Research Projects Agency awarding US$65 million. Calls for a global moratorium on RNA-mediated genetic engineering may overstate the potential risks of the developing technology, but form a background to the contest between "process"- and "product" -based approaches to regulation, the former purportedly favoured by the public and regulatory agencies and the latter favoured by the broad scientific community and corporate investors. At stake may be the democratic legitimacy of and equitable access to a technology that could be important to reduce the incidence of biosecurity threats both globally and in Australia.
- Subject
- CRISPR; genetic technology regulation; biosecurity; gene splicing; malaria; ribonucleic acid research; SDG 3; SDG 13; SDG 15; Sustainable Development Goals
- Identifier
- http://hdl.handle.net/1959.13/1437187
- Identifier
- uon:40267
- Identifier
- ISSN:1320-159X
- Language
- eng
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