- Title
- Is there a difference between EQ-5D and SF-6D in the clinical setting? a comparative study on the quality of life measured by AIMS2-SF, EQ-5D and SF-6D scales for osteoarthritis patients
- Creator
- Zhang, Fang; Yang, Yu; Huang, Tao; Zhang, Yiye; Zhao, Li; Li, Shuchuen
- Relation
- International Journal of Rheumatic Diseases Vol. 21, Issue 6, p. 1185-1192
- Publisher Link
- http://dx.doi.org/10.1111/1756-185X.12907
- Publisher
- Wiley-Blackwell
- Resource Type
- journal article
- Date
- 2018
- Description
- Background: The use of both generic and disease-specific instruments in assessing quality of life (QoL) in subjects may pose a barrier in a busy clinical setting with heavy case load. Our current study attempted to evaluate the responsiveness of generic scales, EQ-5D and SF-6D, as compared with a disease-specific instrument, AIM2-SF, in patients with osteoarthritis, to judge which of the two generic instruments would be more suitable to be used alone in the clinical setting. Methods: Correlation tests with Pearson correlation coefficient were carried out between EQ-5D and SF-6D scales, and AIMS2-SF scale for both 100 first-diagnosed osteoarthritis patients and 22 patients with two follow-up interviews. Multivariate stepwise regression analysis was further performed on the impact of dimensions that affect the change of QoL. Results: In the evaluation of QoL for 100 patients with osteoarthritis by the EQ-5D scale, anxiety was the dimension with the highest sensitivity; while the SF-6D scale had higher sensitivity on two dimensions of psychological health and role limitations. Therefore, SF-6D would appear more suitable for evaluating QoL of arthritis patients at first presentation. For patients at follow-up interviews, EQ-5D scale maintained the highest sensitivity on anxiety and SF-6D scale only had high sensitivity on the psychological health dimension. As such, the two scales would have equivalent effects for the patients at follow-up interviews. In comparison, all the dimensions of SF-6D showed significant correlation with practically every dimension of AIMS2-SF. Hence, the overall results indicate SF-6D may be more suitable for use in patients with clinical osteoarthritis.
- Subject
- AIMS2-SF; correlation; EQ-5D; osteoarthritis; quality of life; SF-6D
- Identifier
- http://hdl.handle.net/1959.13/1409433
- Identifier
- uon:36023
- Identifier
- ISSN:1756-1841
- Language
- eng
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