- Title
- Hysterectomy and perceived physical function in middle-aged Australian women: a 20-year population-based prospective cohort study
- Creator
- Wilson, Louise F.; Pandeya, Nirmala; Byles, Julie; Mishra, Gita D.
- Relation
- ARC.CE170100005 http://purl.org/au-research/grants/arc/CE170100005
- Relation
- Quality of Life Research Vol. 27, Issue 6, p. 1501-1511
- Publisher Link
- http://dx.doi.org/10.1007/s11136-018-1812-9
- Publisher
- Springer
- Resource Type
- journal article
- Date
- 2018
- Description
- Purpose: Hysterectomy is one of the most common gynaecological procedures worldwide. Changes in endocrine function may impact age-associated decline in physical function and these changes may be accelerated by hysterectomy. The aim of this study was to investigate associations between hysterectomy status and self-reported physical function limitations. Methods: Our study sample (n = 8624) came from the mid-cohort (born 1945-1950) of the Australian Longitudinal Study on Women's Health (ALSWH). Self-report of physical function was measured by the Physical Functioning (PF) subscale of the Medical Outcomes Study Short Form Health Survey (SF-36) over seven surveys (1998-2016), categorised into substantial, moderate and minimal PF-limitations. The associations between hysterectomy status and de novo substantial or moderate PF-limitations versus minimal PF-limitations were investigated using log-multinomial regression. Results: By Survey 8 (2016), 20% of the study sample had a hysterectomy with ovarian conservation (hysterectomy only) and 9% had a hysterectomy and both ovaries removed (hysterectomy-bilateral oophorectomy). Women with a hysterectomy only had a small increase in risk of substantial PF-limitations (versus minimal PF-limitations) compared to women with no hysterectomy (relative risk [RR]: 1.13; 95% confidence interval [95% CI] 1.00-1.27); the point estimate was stronger for women with a hysterectomy-bilateral oophorectomy (RR: 1.26; 95% CI 1.09-1.46). In a supplementary analysis, the increased risk of substantial PF-limitations was seen only in women who had surgery before the age of 45 years. Conclusions: Compared to women with no hysterectomy, women with hysterectomy-bilateral oophorectomy were at increased risk of substantial PF-limitations versus minimal PF-limitations over 18 years of follow-up.
- Subject
- hysterectomy; physical function; bilateral oophorectomy; SF36; women’s health
- Identifier
- http://hdl.handle.net/1959.13/1407631
- Identifier
- uon:35754
- Identifier
- ISSN:0962-9343
- Rights
- This is a post-peer-review, pre-copyedit version of an article published in Archives of Women’s Mental Health. The final authenticated version is available online at: http://dx.doi.org/10.1007/s11136-018-1812-9.
- Language
- eng
- Full Text
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