- Title
- Computed tomography derived bone density measurement in the diabetic foot
- Creator
- Barwick, Alex; Tessier, John; Mirow, James; de Jonge, Xanne Janse; Chuter, Vivienne
- Relation
- Journal of Foot and Ankle Research Vol. 10, no. 11
- Publisher Link
- http://dx.doi.org/10.1186/s13047-017-0192-7
- Publisher
- BioMed Central
- Resource Type
- journal article
- Date
- 2017
- Description
- Background: The accurate and reliable measurement of foot bone density is challenging and there is currently no gold standard technique. Such measurement is particularly valuable in populations at risk of foot bone pathology such as in those with long term diabetes. With research and development, computed tomography may prove to be a useful tool for this assessment. The aim of this study was to establish the reliability of a novel method of foot bone density measurement in people with diabetes using computed tomography. Methods: Ten feet in people with diabetes were scanned with computed tomography twice with repositioning. Bone density (in Hounsfield units) was assessed in the trabecular and cortical bone in all tarsals and metatarsals. Reliability was assessed with intra-class correlation coefficients (95% confidence intervals), limits of agreement and standard error of measurement. Results: The reliability of the trabecular density of most bones was excellent with intra-class correlation coefficients ranging from 0.68 to 0.91. Additionally, cortical bone density showed fair to good reliability at the talus (0.52), calcaneus (0.59), navicular (0.70), cuboid (0.69), intermediate cuneiform (0.46) and first metatarsal (0.61). Conclusions: The study established the reliability of a practical method of assessing the trabecular and cortical foot bone density using computed tomography scanning. This methodology may be useful in the investigation of foot bone disease occurring in diabetes and its early diagnosis, intervention and assessment of treatment efficacy. Further development of this method is warranted.
- Subject
- bone; diabetes; foot; reliability
- Identifier
- http://hdl.handle.net/1959.13/1353054
- Identifier
- uon:31015
- Identifier
- ISSN:1757-1146
- Rights
- © The Author(s). 2017 Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
- Language
- eng
- Full Text
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