- Title
- A review of the effects of chronic arsenic exposure on adverse pregnancy outcomes
- Creator
- Milton, Abul H.; Hussain, Sumaira; Akter, Shahnaz; Rahman, Mijanur; Mouly, Tafzila A.; Mitchell, Kane
- Relation
- International Journal of Environmental Research and Public Health Vol. 14, Issue 6, no. 556
- Publisher Link
- http://dx.doi.org/10.3390/ijerph14060556
- Publisher
- MDPI AG
- Resource Type
- journal article
- Date
- 2017
- Description
- Exposure to arsenic has a number of known detrimental health effects but impact on pregnancy outcomes is not as widely recognized. This narrative review examines existing epidemiological evidence investigating the association between arsenic exposure via drinking water and adverse pregnancy outcomes. We reviewed published epidemiological studies from around the world on impact of chronic arsenic exposure on spontaneous abortion, stillbirth, neonatal death, post neonatal death, low birth weight and preterm baby. Plausible mechanisms of arsenic toxicity causing adverse pregnancy outcomes were also determined through literature review. There is convincing evidence to support the association between high inorganic arsenic exposure (>50 ppb) and spontaneous abortion, stillbirth and low birth weight. Limitations of certain studies include study design, small sample size, recall constraints and exposure assessment. There needs to be further research investigating the dose metered impact of arsenic exposure on pregnancy outcomes. Further research on impact of low–moderate arsenic concentration exposure on pregnancy outcomes will allow for appropriate public health policy recommendations.
- Subject
- arsenic; pregnancy outcomes; chronic exposure; drinking water
- Identifier
- http://hdl.handle.net/1959.13/1348189
- Identifier
- uon:30167
- Identifier
- ISSN:1660-4601
- Rights
- This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).
- Language
- eng
- Full Text
- Reviewed
- Hits: 5575
- Visitors: 5798
- Downloads: 341
Collections
Goal 3: Good Health and Well-Being
| Thumbnail | File | Description | Size | Format | |||
|---|---|---|---|---|---|---|---|
| View Details Download | ATTACHMENT02 | Publisher version (open access) | 299 KB | Adobe Acrobat PDF | View Details Download |