- Title
- No effect of anodal transcranial direct current stimulation over the motor cortex on response-related ERPs during a conflict task
- Creator
- Conley, Alexander C.; Fulham, W. R.; Marquez, J. L.; Parsons, Mark W.; Karayanidis, Frini
- Relation
- Frontiers in Human Neuroscience Vol. 10
- Publisher Link
- http://dx.doi.org/10.3389/fnhum.2016.00384
- Publisher
- Frontiers Research Foundation
- Resource Type
- journal article
- Date
- 2016
- Description
- Anodal transcranial direct current stimulation (tDCS) over the motor cortex is considered a potential treatment for motor rehabilitation following stroke and other neurological pathologies. However, both the context under which this stimulation is effective and the underlying mechanisms remain to be determined. In this study, we examined the mechanisms by which anodal tDCS may affect motor performance by recording event-related potentials (ERPs) during a cued go/nogo task after anodal tDCS over dominant primary motor cortex (M1) in young adults (Experiment 1) and both dominant and non-dominant M1 in older adults (Experiment 2). In both experiments, anodal tDCS had no effect on either response time (RT) or response-related ERPs, including the cue-locked contingent negative variation (CNV) and both target-locked and response-locked lateralized readiness potentials (LRP). Bayesian model selection analyses showed that, for all measures, the null effects model was stronger than a model including anodal tDCS vs. sham. We conclude that anodal tDCS has no effect on RT or response-related ERPs during a cued go/nogo task in either young or older adults.
- Subject
- transcranial direct current stimulation; event-related potential; contingent negative variation; lateralized readiness potential; P300; ageing
- Identifier
- http://hdl.handle.net/1959.13/1337488
- Identifier
- uon:27854
- Identifier
- ISSN:1662-5161
- Rights
- © 2016 Conley, Fulham, Marquez, Parsons and Karayanidis. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution and reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
- Language
- eng
- Full Text
- Reviewed
- Hits: 3408
- Visitors: 3671
- Downloads: 294
Collections
Goal 3: Good Health and Well-Being
| Thumbnail | File | Description | Size | Format | |||
|---|---|---|---|---|---|---|---|
| View Details Download | ATTACHMENT02 | Publisher version (open access) | 1 MB | Adobe Acrobat PDF | View Details Download |