- Title
- Role of omega-3 fatty acids in weight loss and maintenance
- Creator
- Garg, Manohar L.; Wood, Lisa G.
- Relation
- The Omega-3 Fatty Acid Deficiency Syndrome: Opportunities for Disease Prevention p. 233-246
- Relation
- Nutrition and Diet Research Progress
- Relation
- https://www.novapublishers.com/catalog/product_info.php?products_id=38881
- Publisher
- Nova Science Publishers
- Resource Type
- book chapter
- Date
- 2013
- Description
- A main function of adipose tissue is to store surplus energy however providing mechanical support and cushioning vital organs for protection from injury and extremes of weather conditions are equally important functions of body fat. However, excess body fat (overweight/obesity), particularly in the abdominal region has been associated with adverse health effects including diabetes mellitus and cardiovascular disease. In recent years, adipose tissue has been recognized as an endocrine gland actively secreting hormones, cytokines and other regulatory substances that play important role in energy balance, glucose metabolism, regulation of blood pressure and the immune system. Development of obesity is also characterized by a chronic low grade inflammation in the adipose tissue. Epidemiological and interventional studies suggest that bioactive food components such as LCn-3PUFA (eicosapentaenoic acid, EPA and docosahexeanoic acid, DHA) can modulate the inflammatory process and assist in weight loss and/or slow-down weight gain. Expression of genes involved in fat synthesis and oxidation in adipose tissue, coupled with increase in satiety hormones and enhanced blood flow to muscles, appear to mediate weight loss following LCn-3PUFA supplementation. Recent research has also raised the possibility that LCn-3PUFA supplementation may have differential effects on weight loss and body composition in males versus female subjects. Precise mechanisms by which LCn-3PUFA hasten weight loss and/or suppress weight gain merit further investigation, as does the role of EPA versus DHA in weight management.
- Subject
- omega-3 fatty acids; weight loss; weight loss maintenance; adipose tissue
- Identifier
- http://hdl.handle.net/1959.13/1337263
- Identifier
- uon:27804
- Identifier
- ISBN:9781624177033
- Language
- eng
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