- Title
- A parallel modelling algorithm for simulating calcium release in cells
- Creator
- Stoddard, Jeremy G.; Welsh, James S.; Laver, Derek R.
- Relation
- 6th IFAC Conference on Foundations of Systems Biology in Engineering (FOSBE 2016). Proceedings of the 6th IFAC Conference on Foundations of Systems Biology in Engineering [presented in IFAC Papers Online, Vol. 49 No. 26] (Magdeburg, Germany 9-12 October, 2016) p. 83-88
- Publisher Link
- http://dx.doi.org/10.1016/j.ifacol.2016.12.107
- Publisher
- International Federation of Control (IFAC)
- Resource Type
- conference paper
- Date
- 2016
- Description
- Using a spatially discretised model structure to represent the behaviour of calcium release sites in a cell, this paper presents a parallel solution algorithm which treats each release site as an independent sub-system, and manages inter-site data communication on a global timestep. When compared to the equivalent single-thread solution algorithm, the parallel method features a negligible reduction in accuracy, and improves computation time scaling from a quadratic, O(n²) to a linear, O(n), with respect to the number of release sites, n, in the model.
- Subject
- parallel; modelling; biology; simulation
- Identifier
- http://hdl.handle.net/1959.13/1335994
- Identifier
- uon:27525
- Identifier
- ISSN:2405-8963
- Language
- eng
- Full Text
- Reviewed
- Hits: 1587
- Visitors: 2157
- Downloads: 423
| Thumbnail | File | Description | Size | Format | |||
|---|---|---|---|---|---|---|---|
| View Details Download | ATTACHMENT02 | Author final version | 449 KB | Adobe Acrobat PDF | View Details Download |