- Title
- Functional dyspepsia
- Creator
- Talley, Nicholas J.; Ford, Alexander C.
- Relation
- New England Journal of Medicine Vol. 373, Issue 19, p. 1853-1863
- Publisher Link
- http://dx.doi.org/10.1056/NEJMra1501505
- Publisher
- Massachusetts Medical Society
- Resource Type
- journal article
- Date
- 2015
- Description
- Dyspepsia is a constellation of symptoms referable to the gastroduodenal region of the upper gastrointestinal tract. Functional dyspepsia, a relapsing and remitting disorder, is the most common cause of these symptoms. The current standard for the diagnosis of functional dyspepsia is the Rome III criteria, developed by the Rome III Committees, a multinational group of experts in the field, first convened in 1990, that meets regularly to review and revise the diagnostic criteria for all functional gastrointestinal disorders. In most patients with functional dyspepsia, the natural history is chronic and fluctuating, with periods of time when the patient is asymptomatic followed by episodes of symptom relapse. Data from population-based studies suggest that, during extended follow-up, approximately 15 to 20% of people with functional dyspepsia have persistent symptoms and 50% have resolution of symptoms; in the remaining 30 to 35% of patients symptoms will fluctuate and meet the criteria for another functional gastrointestinal disorder.81 Despite the chronic nature of functional dyspepsia, there is no evidence to suggest that it is associated with decreased survival.
- Subject
- functional dyspepsia; Helicobacter pylori; gastroparesis; review
- Identifier
- http://hdl.handle.net/1959.13/1329918
- Identifier
- uon:26272
- Identifier
- ISSN:0028-4793
- Language
- eng
- Reviewed
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