Utilisation of MR spectroscopy and diffusion weighted imaging in predicting and monitoring of breast cancer response to chemotherapy

Title: Utilisation of MR spectroscopy and diffusion weighted imaging in predicting and monitoring of breast cancer response to chemotherapy
Creator: Leong, Kin Men; Lau, Peter; Ramadan, Saadallah
Relation: Journal of Medical Imaging and Radiation Oncology Vol. 59, p. 268-277
Publisher Link: http://dx.doi.org/10.1111/1754-9485.12310
Publisher: Blackwell Publishing
Resource Type: journal article
Date: 2015
Description: Summary: Neoadjuvant chemotherapy (NACT) is the standard treatment option for breast cancer as more data shows that pathologic complete response (pCR) after NACT correlates with improved prognosis. MRI is accepted as the best imaging modality for evaluating the response to NACT in many studies as compared with clinical examination and other imaging modalities. In vivo magnetic resonance spectroscopy (MRS) and diffusion-weighted imaging (DWI) studies have both emerged as potential tools to provide early response indicators based on the changes in the metabolites and the apparent diffusion coefficient (ADC) respectively. In this review article, we aim to discuss the strength and limitations of MRS and DWI in monitoring of early response breast cancer to NACT.
Subject: breast cancer; diffusion weighted imaging; magnetic resonance imaging; magnetic resonance spectroscopy; neoadjuvant chemotherapy
Identifier: http://hdl.handle.net/1959.13/1327332
Identifier: uon:25640
Identifier: ISSN:1754-9477
Language: eng
Reviewed

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