- Title
- Repurposing some older drugs that cross the blood-brainier and have potential anticancer activity to provide new treatment options for glioblastoma
- Creator
- Rundle-Thiele, Dayle; Head, Richard; Cosgrove, Leah; Martin, Jennifer H.
- Relation
- British Journal of Clinical Pharmacology Vol. 81, Issue 2, p. 199-209
- Publisher Link
- http://dx.doi.org/10.1111/bcp.12785
- Publisher
- Wiley-Blackwell
- Resource Type
- journal article
- Date
- 2016
- Description
- Glioblastoma is a brain neoplasm with limited 5-year survival rates. Developments of new treatment regimens that improve patient survival in patients with glioblastoma are needed. It is likely that a number of existing drugs used in other conditions have potential anticancer effects that offer significant survival benefit to glioblastoma patients. Identification of such drugs could provide a novel treatment paradigm.
- Subject
- antidepressants; antiepileptic drugs; antihypertensive; beta-blockers; glioblastoma; statins
- Identifier
- http://hdl.handle.net/1959.13/1320313
- Identifier
- uon:24125
- Identifier
- ISSN:0306-5251
- Language
- eng
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