Anaphase-promoting complex control in female mouse meiosis

Title: Anaphase-promoting complex control in female mouse meiosis
Creator: Jones, Keith T.
Relation: ARC, NHMRC
Relation: Cell Cycle in Development p. 343-363
Publisher Link: http://dx.doi.org/10.1007/978-3-642-19065-0_15
Publisher: Springer-Verlag
Resource Type: book chapter
Date: 2011
Description: Entry into, and passage through, the two meiotic divisions of the oocyte has to be highly coordinated to ensure proper segregation of chromosomes. This coordination ensures that the hallmark stops and starts of the meiotic process occur at the right time to prevent aneuploidy. The Anaphase-Promoting Complex is an activity mostly studied in the mitotic cell cycle division, where it has essential functions during mitosis. As detailed here the Anaphase-Promoting Complex also plays vital roles in controlling at least three meiotic events: maintenance of prophase I arrest, timely and faithful segregation of homologous chromosomes in meiosis I, and the meiotic arrest following ovulation.
Subject: oocytes; meiosis; mice; anaphase-promoting
Identifier: http://hdl.handle.net/1959.13/1316595
Identifier: uon:23214
Identifier: ISBN:9783642190643
Language: eng

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