Clinical staging: a necessary step in the development of improved animal models of mood disturbance?

Title: Clinical staging: a necessary step in the development of improved animal models of mood disturbance?
Creator: Walker, Frederick Rohan; James, Morgan H.; Hickie, Ian B.; McGorry, Patrick D.
Relation: International Journal of Neuropsychopharmacology Vol. 17, Issue 3, p. 491-495
Publisher Link: http://dx.doi.org/10.1017/S1461145713001107
Publisher: Oxford University Press
Resource Type: journal article
Date: 2014
Description: Recently, it has been suggested that the clinical staging approach be considered a serious alternative framework for conceptualising mood related psychopathology. The fundamental difference between clinical staging and the now dominant categorical diagnostic framework is that the entire illness trajectory becomes relevant, as opposed to simply the end-stage. The concept of disease trajectory has significant implications for animal models of psychopathology, and particularly for animal models of depression. This article will introduce and discuss the implications of the clinical staging approach for those undertaking research using animal models of mood disturbance.
Subject: animal models of depression; clinical staging; depression; mood disorders
Identifier: http://hdl.handle.net/1959.13/1065560
Identifier: uon:17867
Identifier: ISSN:1469-5111
Language: eng
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