https://nova.newcastle.edu.au/vital/access/manager/Index ${session.getAttribute("locale")} 5 https://nova.newcastle.edu.au/vital/access/manager/Repository/uon:48703 Wed 29 Mar 2023 14:08:59 AEDT ]]> https://nova.newcastle.edu.au/vital/access/manager/Repository/uon:50112 Wed 28 Feb 2024 16:20:34 AEDT ]]> https://nova.newcastle.edu.au/vital/access/manager/Repository/uon:53591 Wed 28 Feb 2024 16:00:08 AEDT ]]> https://nova.newcastle.edu.au/vital/access/manager/Repository/uon:53917 Wed 28 Feb 2024 15:39:13 AEDT ]]> https://nova.newcastle.edu.au/vital/access/manager/Repository/uon:53798 Wed 28 Feb 2024 15:24:53 AEDT ]]> https://nova.newcastle.edu.au/vital/access/manager/Repository/uon:45277 0.14). Conclusion: In this secondary analysis of a primary efficacy study, PD was a common comorbidity among those with MDD, but was not a significant predictor of functional outcomes. This study adds to the limited literature on PD in randomized controlled trials for MDD.]]> Wed 26 Oct 2022 17:13:15 AEDT ]]> https://nova.newcastle.edu.au/vital/access/manager/Repository/uon:54877 Wed 20 Mar 2024 13:18:34 AEDT ]]> https://nova.newcastle.edu.au/vital/access/manager/Repository/uon:40895 Wed 20 Jul 2022 09:32:18 AEST ]]> https://nova.newcastle.edu.au/vital/access/manager/Repository/uon:38720 Wed 19 Jan 2022 09:22:02 AEDT ]]> https://nova.newcastle.edu.au/vital/access/manager/Repository/uon:48953 Wed 19 Apr 2023 12:42:21 AEST ]]> https://nova.newcastle.edu.au/vital/access/manager/Repository/uon:38246 Wed 18 Aug 2021 15:42:37 AEST ]]> https://nova.newcastle.edu.au/vital/access/manager/Repository/uon:53778 Wed 13 Mar 2024 19:07:43 AEDT ]]> https://nova.newcastle.edu.au/vital/access/manager/Repository/uon:38764 Wed 13 Mar 2024 14:30:44 AEDT ]]> https://nova.newcastle.edu.au/vital/access/manager/Repository/uon:38833 Wed 13 Mar 2024 13:57:46 AEDT ]]> https://nova.newcastle.edu.au/vital/access/manager/Repository/uon:51966 Wed 13 Mar 2024 07:44:19 AEDT ]]> https://nova.newcastle.edu.au/vital/access/manager/Repository/uon:39815 I² statistic. This systematic review was registered with PROSPERO (CRD42018089279) and the protocol is published. Results: The search yielded 11,640 studies. Subsequent to removing duplicates, 9657 studies were screened at title and abstract stage and 1456 were assessed at full-text stage. Eighteen studies met criteria for inclusion in this review. Meta-analysis did not reveal a significant difference between groups for treatment outcome (standardised mean difference 0.22 [-0.09, 0.54]; I²: 69%, p=0.17) and remission (risk ratio 0.84 [0.64, 1.11]; I²: 51%, p=0.22). Limitations: This review was limited by lack of studies on bipolar disorder. Conclusion: PD comorbidity does not appear to affect treatment efficacy of pharmacological interventions for adults with mood disorders.]]> Wed 10 Aug 2022 13:16:51 AEST ]]> https://nova.newcastle.edu.au/vital/access/manager/Repository/uon:39228 Wed 10 Aug 2022 08:45:34 AEST ]]> https://nova.newcastle.edu.au/vital/access/manager/Repository/uon:55098 Wed 10 Apr 2024 08:44:48 AEST ]]> https://nova.newcastle.edu.au/vital/access/manager/Repository/uon:53619 Wed 07 Feb 2024 14:40:08 AEDT ]]> https://nova.newcastle.edu.au/vital/access/manager/Repository/uon:48387 Wed 06 Mar 2024 14:34:39 AEDT ]]> https://nova.newcastle.edu.au/vital/access/manager/Repository/uon:54615 Wed 06 Mar 2024 10:45:30 AEDT ]]> https://nova.newcastle.edu.au/vital/access/manager/Repository/uon:38160 0.05), and the intervention significantly improved the ASI (all p < 0.05). A more favourable ASI score was associated with improved symptoms of depression, anxiety, stress, QOL-mental and of energy and fatigue (all p < 0.05). The intervention effects on symptoms of depression ([AB; 95%CI] -0.31; - 0.60,-0.11), anxiety (- 0.11; - 0.27,-0.01), stress (- 0.37; - 0.65,-0.174), QOL-mental (0.53; 0.22, 1.01) and ratings of energy and fatigue (0.85; 0.33, 1.63) were mediated by ASI. At 6 months the magnitude of association was larger although the overall pattern of results remained similar. Conclusions: Improvements in the overall physical activity and sleep behaviours of adults partially mediated the intervention effects on mental health and quality of life outcomes. This highlights the potential benefit of improving the overall pattern of physical activity and sleep on these outcomes. Trial registration: Australian New Zealand Clinical Trial Registry: ACTRN12617000680369; ACTRN12617000376347. Universal Trial number: U1111–1194-2680; U1111–1186-6588. Human Research Ethics Committee Approval: H-2016- 0267; H-2016–0181.]]> Wed 04 Aug 2021 18:44:37 AEST ]]> https://nova.newcastle.edu.au/vital/access/manager/Repository/uon:38155 Wed 04 Aug 2021 18:23:45 AEST ]]> https://nova.newcastle.edu.au/vital/access/manager/Repository/uon:38560 Wed 02 Aug 2023 11:51:56 AEST ]]> https://nova.newcastle.edu.au/vital/access/manager/Repository/uon:55237 Wed 01 May 2024 15:42:40 AEST ]]> https://nova.newcastle.edu.au/vital/access/manager/Repository/uon:52870 Tue 31 Oct 2023 10:09:21 AEDT ]]> https://nova.newcastle.edu.au/vital/access/manager/Repository/uon:54411 Tue 27 Feb 2024 13:54:50 AEDT ]]> https://nova.newcastle.edu.au/vital/access/manager/Repository/uon:51132 Tue 22 Aug 2023 15:58:09 AEST ]]> https://nova.newcastle.edu.au/vital/access/manager/Repository/uon:51126 Tue 22 Aug 2023 15:51:43 AEST ]]> https://nova.newcastle.edu.au/vital/access/manager/Repository/uon:51127 Tue 22 Aug 2023 15:51:17 AEST ]]> https://nova.newcastle.edu.au/vital/access/manager/Repository/uon:48545 Tue 21 Mar 2023 15:23:47 AEDT ]]> https://nova.newcastle.edu.au/vital/access/manager/Repository/uon:54318 Tue 20 Feb 2024 15:51:10 AEDT ]]> https://nova.newcastle.edu.au/vital/access/manager/Repository/uon:41593 Tue 19 Sep 2023 13:55:52 AEST ]]> https://nova.newcastle.edu.au/vital/access/manager/Repository/uon:52543 Tue 17 Oct 2023 14:24:24 AEDT ]]> https://nova.newcastle.edu.au/vital/access/manager/Repository/uon:41946 Tue 16 Aug 2022 14:31:48 AEST ]]> https://nova.newcastle.edu.au/vital/access/manager/Repository/uon:49886 Tue 13 Jun 2023 13:22:54 AEST ]]> https://nova.newcastle.edu.au/vital/access/manager/Repository/uon:51612 Tue 12 Sep 2023 13:50:31 AEST ]]> https://nova.newcastle.edu.au/vital/access/manager/Repository/uon:44349 Tue 11 Oct 2022 19:35:23 AEDT ]]> https://nova.newcastle.edu.au/vital/access/manager/Repository/uon:39120 n = 4) while no reason was given in four studies. Seven studies reported that through screening, pharmacists could identify adults with undiagnosed depression. Pharmacists referred adults screening positive for assessment in seven studies and followed up participants in two studies. No study assessed the impact of screening on depressive symptoms or the cost-effectiveness of pharmacists screening for depression. Conclusion: Community pharmacists are able to use depression screening tools to identify undiagnosed adults having symptoms of depression. However, there is little evidence around the impact of this screening on clinical and economic outcomes. Larger, well-designed studies that use a highly accurate, easily administered screening tool and include patient referral and follow-up and pharmacist training are warranted to provide evidence on the impact of community pharmacists screening adults for depression.]]> Tue 10 May 2022 17:14:36 AEST ]]> https://nova.newcastle.edu.au/vital/access/manager/Repository/uon:54155 Tue 06 Feb 2024 12:11:04 AEDT ]]> https://nova.newcastle.edu.au/vital/access/manager/Repository/uon:43849 Tue 04 Oct 2022 11:53:52 AEDT ]]> https://nova.newcastle.edu.au/vital/access/manager/Repository/uon:50659 Tue 01 Aug 2023 13:00:02 AEST ]]> https://nova.newcastle.edu.au/vital/access/manager/Repository/uon:39917 Thu 30 Jun 2022 11:48:31 AEST ]]> https://nova.newcastle.edu.au/vital/access/manager/Repository/uon:39830 Thu 28 Jul 2022 08:36:02 AEST ]]> https://nova.newcastle.edu.au/vital/access/manager/Repository/uon:45240 54) in 2013, and who completed at least 1 follow-up survey (2014–2018), were included (n = 10,977). Poor mental health (Mental Health Inventory-5 ≤ 54) was assessed annually. Baseline (2013) PA was classified as high/moderate/low, and insomnia symptoms (i.e., trouble sleeping) were classified as no insomnia symptoms/insomnia symptoms, with 6 mutually exclusive PA-insomnia symptom groups derived. Associations of PA–insomnia symptom groups with onset of poor mental health were examined using discrete-time proportional-hazards logit-hazard models. Results: There were 2322 new cases of poor mental health (21.2%). Relative to the high PA/no insomnia symptoms group, there were higher odds (odds ratio, 95% confidence interval (95%CI)) of poor mental health among the high PA/insomnia symptoms (OR = 1.87, 95%CI: 1.57–2.23), moderate PA/insomnia symptoms (OR = 1.93, 95%CI: 1.61–2.31), low PA/insomnia symptoms (OR = 2.33, 95%CI: 1.96–2.78), and low PA/no insomnia symptoms (OR = 1.14, 95%CI: 1.01–1.29) groups. Any level of PA combined with insomnia symptoms was associated with increased odds of poor mental health, with the odds increasing as PA decreased. Conclusion: These findings highlight the potential benefit of interventions targeting both PA and insomnia symptoms for promoting mental health. [Final Citation details pending]]]> Thu 27 Oct 2022 12:35:23 AEDT ]]> https://nova.newcastle.edu.au/vital/access/manager/Repository/uon:51873 Thu 21 Sep 2023 10:23:09 AEST ]]> https://nova.newcastle.edu.au/vital/access/manager/Repository/uon:54918 Thu 21 Mar 2024 13:12:47 AEDT ]]> https://nova.newcastle.edu.au/vital/access/manager/Repository/uon:37497 Thu 21 Jan 2021 17:11:20 AEDT ]]> https://nova.newcastle.edu.au/vital/access/manager/Repository/uon:48422 Thu 16 Mar 2023 14:11:06 AEDT ]]> https://nova.newcastle.edu.au/vital/access/manager/Repository/uon:54278 Thu 15 Feb 2024 14:38:24 AEDT ]]> https://nova.newcastle.edu.au/vital/access/manager/Repository/uon:36696 Thu 14 Mar 2024 08:31:28 AEDT ]]> https://nova.newcastle.edu.au/vital/access/manager/Repository/uon:38637 Thu 14 Mar 2024 08:30:25 AEDT ]]> https://nova.newcastle.edu.au/vital/access/manager/Repository/uon:40074 n = 1831) to evaluate if inflammation and central adiposity mediate the relationship between depression and diabetes. Methods: Depression was estimated using a behavior-based diagnostic algorithm, inflammation using venous dried blood spot (DBS) CRP, central adiposity using waist-to-height ratio (WHtR), and uncontrolled diabetes using venous DBS-glycated hemoglobin (HbA1c). Results: The association between depression and uncontrolled diabetes was partially mediated by CRP before but not after WHtR was considered. When WHtR was added to the model, it partially mediated the relationship between diabetes and depression while fully mediating the relationship between depression and CRP. Conclusions: These findings suggest that central adiposity may be a more significant mediator between diabetes and depression than inflammation and account for the relationship between these disorders and inflammation. Depression may cause an increase in central adiposity, which then may lead to diabetes, but the increase in known systemic inflammatory pathways caused by central adiposity may not be the key pathological mechanism.]]> Thu 14 Jul 2022 12:29:11 AEST ]]> https://nova.newcastle.edu.au/vital/access/manager/Repository/uon:53749 Thu 11 Jan 2024 12:14:35 AEDT ]]> https://nova.newcastle.edu.au/vital/access/manager/Repository/uon:39920 Thu 11 Aug 2022 14:36:04 AEST ]]> https://nova.newcastle.edu.au/vital/access/manager/Repository/uon:55127 Thu 11 Apr 2024 11:14:46 AEST ]]> https://nova.newcastle.edu.au/vital/access/manager/Repository/uon:50194 Thu 06 Jul 2023 15:51:19 AEST ]]> https://nova.newcastle.edu.au/vital/access/manager/Repository/uon:38356 Mon 30 Aug 2021 16:11:44 AEST ]]> https://nova.newcastle.edu.au/vital/access/manager/Repository/uon:44797 Mon 24 Oct 2022 09:25:04 AEDT ]]> https://nova.newcastle.edu.au/vital/access/manager/Repository/uon:39178 Mon 23 May 2022 16:23:30 AEST ]]> https://nova.newcastle.edu.au/vital/access/manager/Repository/uon:38656 n = 10,003; 48.3% women; 48.5[15.7] years), core food score in 2013 was associated with MHI-5 (β:0.102, 95%CI: 0.010,0.193) in 2017, while the non-core food score was not (β:-0.030, 95%CI:-0.099,0.160). Depressive symptom score in 2013 was not associated with either food score in 2017. Current/prior diagnosis of depression in 2013 was associated with core (β:-0.198, 95%CI:-0.329,-0.067) but not non-core (β:-0.036, 95%CI: -0.151,0.080) food score in 2017. Limitations: Results may not be generalizable to the whole population due to some selection bias, self-report depression diagnosis may have led to misclassification of previous mental illness, and core and non-core food scores are not validated measures of diet quality. Conclusions: There is a prospective association between core food consumption and depressive symptoms. This association is of small magnitude and we cannot discount insufficient core food consumption reflecting an effect of prior mental illness. Our results suggest that, for depression, public health focus should be on improving core food intake.]]> Mon 23 May 2022 14:22:55 AEST ]]> https://nova.newcastle.edu.au/vital/access/manager/Repository/uon:49541 Mon 22 May 2023 08:45:28 AEST ]]> https://nova.newcastle.edu.au/vital/access/manager/Repository/uon:42344 Mon 22 Aug 2022 13:54:55 AEST ]]> https://nova.newcastle.edu.au/vital/access/manager/Repository/uon:46393 p = .01), 21 minutes more walking (95%CI 2,22 p = .02) and completed 1112 additional steps/day (95%CI 268,1956 p = .01), compared to the first week home. No factors predicted change in activity. At 3 months, greater depression (β 22 mins (95%CI 8,36) p = .004) and slower gait speed (β − 43 mins 95%CI −59,-27 p ≤ 0.001) were associated with more sedentary time and less walking activity, respectively. Conclusions: Sedentary time reduced and walking activity increased between discharge home and 3 months later. Interventions targeting mood and physical function may warrant testing to reduce sedentary behavior 3 months following discharge.]]> Mon 21 Nov 2022 14:45:55 AEDT ]]> https://nova.newcastle.edu.au/vital/access/manager/Repository/uon:51077 Mon 21 Aug 2023 11:09:07 AEST ]]> https://nova.newcastle.edu.au/vital/access/manager/Repository/uon:41915 14). Limitations: The lack of a control group and the absence of a complete clinical assessment at the follow-up limit the interpretability of our results. Conclusions: Our data driven analysis suggest insomnia heterogeneity can be categorized into sub-classes by depression, anxiety, and stress symptoms. In addition, insomnia patients with stress and depression symptoms maintained highest percentage of clinical depression at the end-of-treatment and insomnia at follow-up, in comparison with others classes. Stress and depression symptoms should be considered risk factors that play an important role in the long-term outcome of CBT-I.]]> Mon 15 Aug 2022 16:00:33 AEST ]]> https://nova.newcastle.edu.au/vital/access/manager/Repository/uon:46279 Mon 14 Nov 2022 15:35:09 AEDT ]]> https://nova.newcastle.edu.au/vital/access/manager/Repository/uon:46203 Mon 14 Nov 2022 11:29:55 AEDT ]]> https://nova.newcastle.edu.au/vital/access/manager/Repository/uon:46195 Mon 14 Nov 2022 11:16:05 AEDT ]]> https://nova.newcastle.edu.au/vital/access/manager/Repository/uon:50952 overall) detected no genome-wide significant hits and showed low single nucleotide polymorphism (SNP) heritability (1.66%, 95% CI = 0.84-2.48%, n_effective = 132,260). Stratified analyses indicated rater-based heterogeneity in genetic effects, with self-reported internalizing symptoms showing the highest heritability (5.63%, 95% CI = 3.08%-8.18%). The contribution of additive genetic effects on internalizing symptoms appeared to be stable over age, with overlapping estimates of SNP heritability from early childhood to adolescence. Genetic correlations were observed with adult anxiety, depression, and the well-being spectrum (|r_g| > 0.70), as well as with insomnia, loneliness, attention-deficit/hyperactivity disorder, autism, and childhood aggression (range |r_g| = 0.42-0.60), whereas there were no robust associations with schizophrenia, bipolar disorder, obsessive-compulsive disorder, or anorexia nervosa. Conclusion: Genetic correlations indicate that childhood and adolescent internalizing symptoms share substantial genetic vulnerabilities with adult internalizing disorders and other childhood psychiatric traits, which could partially explain both the persistence of internalizing symptoms over time and the high comorbidity among childhood psychiatric traits. Reducing phenotypic heterogeneity in childhood samples will be key in paving the way to future GWAS success.]]> Mon 14 Aug 2023 14:36:09 AEST ]]> https://nova.newcastle.edu.au/vital/access/manager/Repository/uon:50230 Mon 10 Jul 2023 14:00:54 AEST ]]> https://nova.newcastle.edu.au/vital/access/manager/Repository/uon:52335 Mon 09 Oct 2023 14:50:31 AEDT ]]> https://nova.newcastle.edu.au/vital/access/manager/Repository/uon:37946 Mon 05 Jul 2021 19:19:42 AEST ]]> https://nova.newcastle.edu.au/vital/access/manager/Repository/uon:51396 Mon 04 Sep 2023 14:43:02 AEST ]]> https://nova.newcastle.edu.au/vital/access/manager/Repository/uon:51391 Mon 04 Sep 2023 13:47:42 AEST ]]> https://nova.newcastle.edu.au/vital/access/manager/Repository/uon:53541 Mon 04 Dec 2023 15:52:08 AEDT ]]> https://nova.newcastle.edu.au/vital/access/manager/Repository/uon:50072 Fri 30 Jun 2023 11:20:33 AEST ]]> https://nova.newcastle.edu.au/vital/access/manager/Repository/uon:50557 Fri 28 Jul 2023 10:53:26 AEST ]]> https://nova.newcastle.edu.au/vital/access/manager/Repository/uon:46474 N = 220) with current depressive symptoms and alcohol misuse were recruited from the DAISI project, a randomised controlled trial with four treatment arms. PTSD symptoms were assessed at baseline by the Posttraumatic Stress Diagnostic Scale and again at the 3-month assessment. Results: McNemars t-test assessed for changes in PTSD symptom severity and PTSD symptom clusters at the 3-month assessment. Repeated measures multivariate analysis of variance assessed for changes in PTSD symptoms, by DAISI treatment allocation. At the 3-month assessment, participants with PTSD reported significant reductions in PTSD symptoms (except intrusion) and a lower rate of PTSD, and responded better to integrated depression-alcohol misuse CBT than to the alcohol/depression single-focussed or brief interventions. Conclusion: Integrated depression and alcohol misuse CBT may be effective for PTSD symptoms, but intrusions may need to be addressed specifically.]]> Fri 25 Nov 2022 15:45:27 AEDT ]]> https://nova.newcastle.edu.au/vital/access/manager/Repository/uon:46590 Fri 25 Nov 2022 15:00:37 AEDT ]]> https://nova.newcastle.edu.au/vital/access/manager/Repository/uon:39813 Fri 24 Jun 2022 09:35:06 AEST ]]> https://nova.newcastle.edu.au/vital/access/manager/Repository/uon:51925 Fri 22 Sep 2023 11:00:16 AEST ]]> https://nova.newcastle.edu.au/vital/access/manager/Repository/uon:38673 N = 27). At cutoff 10, the PHQ-8 was less sensitive by 0.02 (−0.06 to 0.00) and more specific by 0.01 (0.00 to 0.01) among those studies (N = 27), with similar results for studies that used other types of interviews (N = 27). For all 54 primary studies combined, across all cutoffs, the PHQ-8 was less sensitive than the PHQ-9 by 0.00 to 0.05 (0.03 at cutoff 10), and specificity was within 0.01 for all cutoffs (0.00 to 0.01). Conclusions: PHQ-8 and PHQ-9 total scores were similar. Sensitivity may be minimally reduced with the PHQ-8, but specificity is similar.]]> Fri 22 Apr 2022 15:27:36 AEST ]]> https://nova.newcastle.edu.au/vital/access/manager/Repository/uon:39167 Fri 20 May 2022 16:17:36 AEST ]]> https://nova.newcastle.edu.au/vital/access/manager/Repository/uon:53849 Fri 19 Jan 2024 10:25:16 AEDT ]]> https://nova.newcastle.edu.au/vital/access/manager/Repository/uon:53135 Fri 17 Nov 2023 11:57:26 AEDT ]]> https://nova.newcastle.edu.au/vital/access/manager/Repository/uon:48460 .05) in the number of MoodGYM modules completed between the two groups. Discussion and conclusion: The current trial found no benefit to providing a brief online intervention for hazardous alcohol consumption alongside one for depression among people experiencing these co-occurring disorders. Further, the finding that adding an online intervention for drinking to one for depression led to a small reduction in the number of times the interventions were accessed implies the need for caution when deciding how best to provide online help to those with co-occurring depression and hazardous alcohol consumption. Trial Registration: ClinicalTrials.gov NCT03421080.]]> Fri 17 Mar 2023 12:07:36 AEDT ]]> https://nova.newcastle.edu.au/vital/access/manager/Repository/uon:39704 Fri 17 Jun 2022 16:56:05 AEST ]]> https://nova.newcastle.edu.au/vital/access/manager/Repository/uon:47232 Fri 16 Dec 2022 12:08:56 AEDT ]]> https://nova.newcastle.edu.au/vital/access/manager/Repository/uon:39119 Fri 16 Dec 2022 12:01:46 AEDT ]]> https://nova.newcastle.edu.au/vital/access/manager/Repository/uon:51743 Fri 15 Sep 2023 18:13:44 AEST ]]> https://nova.newcastle.edu.au/vital/access/manager/Repository/uon:40583 Fri 15 Jul 2022 10:46:19 AEST ]]> https://nova.newcastle.edu.au/vital/access/manager/Repository/uon:49424 Fri 12 May 2023 15:09:21 AEST ]]> https://nova.newcastle.edu.au/vital/access/manager/Repository/uon:49368 Fri 12 May 2023 12:49:06 AEST ]]> https://nova.newcastle.edu.au/vital/access/manager/Repository/uon:51537 Fri 08 Sep 2023 13:06:14 AEST ]]> https://nova.newcastle.edu.au/vital/access/manager/Repository/uon:51535 Fri 08 Sep 2023 12:31:27 AEST ]]> https://nova.newcastle.edu.au/vital/access/manager/Repository/uon:51508 Fri 08 Sep 2023 12:04:19 AEST ]]> https://nova.newcastle.edu.au/vital/access/manager/Repository/uon:51498 Fri 08 Sep 2023 11:55:55 AEST ]]> https://nova.newcastle.edu.au/vital/access/manager/Repository/uon:45715 Fri 04 Nov 2022 09:31:10 AEDT ]]> https://nova.newcastle.edu.au/vital/access/manager/Repository/uon:38253 Fri 03 Sep 2021 14:46:19 AEST ]]>