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Date: 2009
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.13/807212
Description: Mature mammalian eggs are ovulated arrested at meiotic metaphase II. Sperm break this arrest by an oscillatory Ca²⁺ signal that is necessary and sufficient for the two immediate events of egg activati... More
Reviewed: Reviewed
Date: 2007
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.13/44517
Description: The spastic mouse has a naturally occurring glycine receptor (GlyR) mutation that disrupts synaptic input in both motor and sensory pathways. Here we use the spastic mouse to examine how this altered ... More
Reviewed: Reviewed
Creators: Lee, Yun Hwa
Date: 2008
Language: eng
Resource Type: thesis
Identifier: http://hdl.handle.net/1959.13/33073
Description: Research Doctorate - Doctor of Philosophy
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Date: 2004
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.13/804172
Description: Metaphase II-arrested mouse eggs are stimulated to complete meiosis by sperm-induced Ca²⁺ spiking. The Ca²⁺ signal causes activation of the E3 ligase anaphasepromoting complex/cyclosome (APC), leading... More
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Reviewed: Reviewed
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Date: 1998
Language: eng
Resource Type: journal article
Identifier: uon:6548
Description: Mouse sperm-egg fusion was examined using twophoton and confocal microscopy. A delay of several minutes occurred between the first observable event of fusion (which was the diffusion of Ca²⁺-sensitive... More
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Reviewed: Reviewed
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Date: 1996
Keyword: Ca²⁺ | embryos | mitosis | mouse | mitotic
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.13/804180
Description: We have used Ca²⁺-sensitive fluorescent dyes to monitor intracellular Ca²⁺ during mitosis in one-cell mouse embryos. We find that fertilized embryos generate Ca²⁺ transients at nuclear envelope breakd... More
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Reviewed: Reviewed
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Date: 2004
Language: eng
Resource Type: conference paper
Identifier: http://hdl.handle.net/1959.13/32684
Description: Prior to fertilisation, mammalian spermatozoa undergo a series of molecular and biochemical events that render them capable of interacting with the oocyte. This process, termed capacitation, has been ... More
Date: 2010
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.13/923291
Description: Primordial germ cells (PGCs) are embryonic progenitors for the gametes. In the gastrulating mouse embryo, a small group of cells begin expressing a unique set of genes and so commit to the germline. O... More
Reviewed: Reviewed
Date: 2004
Language: eng
Resource Type: journal article
Identifier: uon:6574
Description: Mammalian eggs naturally arrest at metaphase of the second meiotic division, until sperm triggers a series of Ca²⁺ spikes that result in activation of the anaphase-promoting complex/cyclosome (APC/C).... More
Reviewed: Reviewed
Date: 2009
Resource Type: journal article
Identifier: uon:7891
Description: Upon ejaculation, spermatozoa undergo a series of post-translational modifications in a process known as capacitation in order to prepare for fertilization. In the absence of capacitation, fertilizati... More
Reviewed: Reviewed
Date: 2011
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.13/936944
Description: The mode of synaptic transmission in the vestibular periphery, between type I hair cells and their associated calyx terminal, has been the subject of much debate. The close and extensive apposition of... More
Reviewed: Reviewed
Creators: Roy, Tammie K.
Date: 2011
Language: eng
Resource Type: thesis
Identifier: http://hdl.handle.net/1959.13/927259
Description: Research Doctorate - Doctor of Philosophy (PhD)
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Date: 2010
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.13/932385
Description: The process of vestibular compensation includes both behavioral and neuronal recovery after unilateral loss of peripheral vestibular organs. The mechanisms that underlie this process are poorly unders... More
Reviewed: Reviewed
Date: 2008
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.13/43409
Description: Rationale: Although epidemiological studies have linked asthma susceptibility and severity to polymorphisms in human glutathione transferase Pi (GSTP) 1, there is no direct evidence for a functional i... More
Reviewed: Reviewed
Date: 2005
Resource Type: journal article
Identifier: uon:1255
Description: Fertilization is a unique and exquisitely choreographed cellular interaction between the male and female gamete that results in the creation of a genetically unique individual. Despite the fundamental... More
Reviewed: Reviewed