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Date: 2015
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.13/1335138
Description: Human spermatozoa are compromised by production of reactive oxygen species (ROS), and detection of ROS in spermatozoa is important for the diagnosis of male infertility. The probes 2',7'-dichlorohydro... More
Reviewed: Reviewed
Date: 2015
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.13/1338329
Description: Oxidative stress is known to compromise human sperm function and to activate the intrinsic apoptotic cascade in these cells.One of the key features of oxidatively stressed spermatozoa is the induction... More
Reviewed: Reviewed
Date: 2013
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.13/1300225
Description: DNA repair has long been considered impossible in human spermatozoa due to the high level of DNA compaction observed in these cells. However, detailed examination of the base excision repair pathway i... More
Reviewed: Reviewed
Date: 2013
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.13/1300170
Description: The discovery of a truncated base excision repair pathway in human spermatozoa mediated by OGG1 has raised questions regarding the effect of mutations in critical DNA repair genes on the integrity of ... More
Reviewed: Reviewed
Date: 2012
Language: eng
Resource Type: book chapter
Identifier: http://hdl.handle.net/1959.13/1336644
Description: Oxidation of lipids can be a blessing or a curse as far as spermatozoa are concerned. Beatitudes are conferred via the oxidative generation of oxysterols, which then drive sperm capacitation by promot... More
Date: 2011
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.13/1325349
Description: Background: The purpose of this study was to optimize the electrophoretic conditions that should be used for the effective isolation of functional human spermatozoa and to determine whether this metho... More
Reviewed: Reviewed
Creators: Aitken, R. J.
Date: 2011
Language: eng
Resource Type: book chapter
Identifier: http://hdl.handle.net/1959.13/1046149
Description: The development of safe, effective, efficient methods for the isolation of human spermatozoa is a major feature of current research into the optimization of assisted conception therapy. The objective ... More
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Date: 2011
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.13/1062927
Description: Oxidative stress in the male germ line is thought to affect male fertility and impact upon normal embryonic development. Accordingly, fertility specialists are actively exploring the diagnosis of such... More
Reviewed: Reviewed
Date: 2010
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.13/931915
Description: The purpose of this study was to examine the impact of prolactin (PRL) on human sperm function, in light of a recent proteomic analysis indicating that these cells express the PRL receptor (PRLR). Imm... More
Reviewed: Reviewed
Date: 2010
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.13/927454
Description: Male infertility is a relatively common condition affecting 1 in 20 men of reproductive age. The etiology of this condition is thought to involve the excessive generation of reactive oxygen species by... More
Reviewed: Reviewed
Date: 2009
Resource Type: journal article
Identifier: uon:7946
Description: Background: In recent times there has been some controversy over the impact of electromagnetic radiation on human health. The significance of mobile phone radiation on male reproduction is a key eleme... More
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Reviewed: Reviewed
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Date: 2006
Resource Type: journal article
Identifier: uon:1079
Description: Context: Defective sperm function is the largest defined cause of human infertility; however, the etiology of this condition is poorly understood. Although oxidative stress is acknowledged as a key co... More
Reviewed: Reviewed
Date: 2006
Resource Type: journal article
Identifier: uon:1163
Description: Context: Oxidative stress in the male germ line has been associated with poor fertility, impaired embryonic development, miscarriage, and childhood disease. Such stress is known to be associated with ... More
Reviewed: Reviewed
Date: 2005
Language: eng
Resource Type: journal article
Identifier: uon:27
Description: Background: Optimization of assisted conception outcomes involves the development of rapid, safe, effective techniques for the isolation of functional human spermatozoa free from significant DNA damag... More
Reviewed: Reviewed
Date: 2005
Resource Type: journal article
Identifier: uon:1630
Description: BACKGROUND: Optimization of assisted conception outcomes involves the development of rapid, safe, effective techniques for the isolation of functional human spermatozoa free from significant DNA damag... More
Reviewed: Reviewed