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Creators: Laver, Derek R.
Date: 2010
Language: eng
Resource Type: book chapter
Identifier: http://hdl.handle.net/1959.13/932330
Description: This chapter gives the current picture of how calcium release channels (ryanodine receptors, RyRs) in the sarcoplasmic reticulum (SR) are regulated by intracellular ligands. The review focuses on Ca²⁺... More
Creators: Laver, Derek R.
Date: 2009
Resource Type: journal article
Identifier: uon:7011
Description: The ryanodine receptors form the calcium release channel in the membrane of the sarcoplasmic reticulum (SR, the main intracellular Ca²⁺ store). The importance of ryanodine receptors (RyRs) to cardiac ... More
Reviewed: Reviewed
Date: 2008
Resource Type: journal article
Identifier: uon:5571
Description: The clustering of cardiac RyR mutations, linked to sudden cardiac death (SCD), into several regions in the amino acid sequence underlies the hypothesis that these mutations interfere with stabilising ... More
Reviewed: Reviewed
Creators: Laver, Derek R.
Date: 2007
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.13/44498
Description: 1. In muscle, intracellular calcium concentration, hence skeletal muscle force and cardiac output, is regulated by uptake and release of calcium from the sarcoplasmic reticulum. The ryanodine receptor... More
Reviewed: Reviewed
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