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Date: 2014
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.13/1295774
Description: Calcium ions act as messengers in a broad range of processes such as learning, apoptosis, and muscular movement. The transient profile and the temporal accumulation of calcium signals have been sugges... More
Reviewed: Reviewed
Date: 2013
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.13/1036523
Description: Here we investigate how ß-adrenergic stimulation of the heart alters regulation of ryanodine receptors (RyRs) by intracellular Ca²⁺ and Mg²⁺ and the role of these changes in SR Ca²⁺ release. RyRs were... More
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Date: 2013
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.13/1301017
Description: The factors responsible for the regulation of regenerative calcium-induced calcium release (CICR) during Ca²⁺ spark evolution remain unclear. Cardiac ryanodine receptor (RyR) gating in rats and sheep ... More
Reviewed: Reviewed
Date: 2007
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.13/804201
Description: Fertilisation in ascidians triggers a series of periodic rises in cytosolic Ca²⁺ that are essential for release from metaphase I arrest and progression through meiosis II. These sperm-triggered Ca²⁺ o... More
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Date: 2007
Language: eng
Resource Type: journal article
Identifier: uon:6549
Description: Oocytes from higher chordates, including man and nearly all mammals, arrest at metaphase of the second meiotic division before fertilization. This arrest is due to an activity that has been termed 'Cy... More
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Reviewed: Reviewed
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Date: 2000
Language: eng
Resource Type: journal article
Identifier: uon:6571
Description: A soluble phospholipase C (PLC) from boar sperm generates InsP₃and hence causes Ca²⁺ release when added to sea urchin egg homogenate. This PLC activity is associated with the ability of sperm extracts... More
Reviewed: Reviewed
Creators: Jones, Keith T.
Date: 1998
Language: eng
Resource Type: journal article
Identifier: uon:6594
Description: At fertilization the union of the sperm and egg has two important functions: it brings together their genetic components and it triggers embryonic development. It is oNen assumed that only the genetic... More
Reviewed: Reviewed
Date: 1998
Language: eng
Resource Type: journal article
Identifier: uon:6600
Description: Activation during fertilization in all animal oocytes is mediated by Ca²⁺ changes. In mammals, a series of Ca²⁺ oscillations is observed lasting a number of hours (Miyazaki et al., 1993; Swann and Ozi... More
Reviewed: Reviewed
Date: 1998
Language: eng
Resource Type: journal article
Identifier: uon:6548
Description: Mouse sperm-egg fusion was examined using twophoton and confocal microscopy. A delay of several minutes occurred between the first observable event of fusion (which was the diffusion of Ca²⁺-sensitive... More
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Date: 1997
Language: eng
Resource Type: journal article
Identifier: uon:6596
Description: Ca²⁺ oscillations can be induced in mammalian eggs and somatic cells by microinjection of a cytosolic sperm protein factor. The nature of the sperm factor-induced Ca²⁺ signaling was investigated by ad... More
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Reviewed: Reviewed
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Date: 1997
Language: eng
Resource Type: journal article
Identifier: uon:6585
Description: At fertilization periodic Ca²⁺ oscillations release oocytes from meiotic arrest. The present study examined whether these oscillations have a long-term role in pre- and postimplantation development, i... More
Reviewed: Reviewed
Date: 1996
Keyword: Ca²⁺ | embryos | mitosis | mouse | mitotic
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.13/804180
Description: We have used Ca²⁺-sensitive fluorescent dyes to monitor intracellular Ca²⁺ during mitosis in one-cell mouse embryos. We find that fertilized embryos generate Ca²⁺ transients at nuclear envelope breakd... More
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Date: 1996
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.13/804305
Description: Ca²⁺ release mechanisms in oocytes are highly sensitive and a number of agents including sperm and inositol trisphosphate (IP₃) generate Ca²⁺ transients. Recently it was shown that this sensitivity de... More
Reviewed: Reviewed
Date: 1996
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.13/804162
Description: Oogenesis involves the production of an oocyte that can undergo fertilization and support early development. The stimulus that initiates embryogenesis is an increase in the concentration of intracellu... More
Reviewed: Reviewed
Date: 1995
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.13/804161
Description: Fertilization of mature mouse oocytes triggered highly repetitive Ca²⁺ oscillations lasting 2-3 h. However, immature oocytes generated only two or three oscillations, which ceased within 1 h. Developm... More
Reviewed: Reviewed
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