Please use this identifier to cite or link to this item: http://hdl.handle.net/1959.13/917784

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Title
A commercial nutraceutical mix metabolic cell-support (MC-S™) inhibits proliferation of cancer cell lines in vitro
Author/Creator
Clark, D. A.;  Adams, M. C.
Institution
The University of Newcastle. Faculty of Science & Information Technology, School of Environmental and Life Sciences
Description
Metabolic Cell Support (MC-S), now manufactured by Clinical Health Pty Ltd, is an over the counter immune supplement developed in Australia. Rather than using individual bioactive chemicals, a combined highly standardised multipolysaccharide enriched mix of medicinal mushrooms, the herb Astragalus mebranasis and ascorbic acid was formulated so as not to exclude important components of the original herb that may play a role in clinical outcomes. To examine the potential effect of MC-S on cancer, an in vitro proliferation study using diverse types of cancer cell lines was undertaken. Breast (MCF-7), prostate (DU145), melanoma (MM200) and colon (HT29) cancer cells were cultured under controlled standard conditions in the presence of MC-S at varying doses. After 48 and 72 hours of incubation, proliferation was measured using CellTiter 96 AQueous Non-Radioactive Cell proliferation assay kit. Results MC-S significantly inhibited the growth of breast, prostate, melanoma and bowl cancer cells, over a broad range of doses. Conclusions MC-S in this study was shown to inhibit cancer cell growth. This result, along with previous studies identifying immune stimulation properties, suggests that MC-S may offer additional benefit to standard cancer therapies.
Relation
Australian Journal of Medical Herbalism Vol. 21, Issue 2, p. 39-43
Relation
http://www.nhaa.org.au/index.php?option=com_content&view=article&id=360&Itemid=259
Date
2009
Publisher
National Herbalists Association of Australia
Keyword(s)
metabolic cell support (MC-S),;  immune supplement;  cancer;  cell growth
Resource Type
journal article
Identifier
http://hdl.handle.net/1959.13/917784
Identifier
ISSN:1033-8330
Reviewed
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Subject
"Australian Journal of Medical Herbalism"
 
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