Lung cancer is one of the most common malignancies in the world. In Australia, lung cancer accounts for 8500 new cases pa, the fifth most common cancer. In addition it is seldom ever cured, with the vast majority of patients succumbing from their disease, accounting for 7000 deaths pa in Australia, the commonest cause of cancer death. In developed countries like Australia, trends in smoking habits are leading to decreasing incidence but it still has a substantial health impact. On the contrary lung cancer has a sharply increasing incidence in developing countries, where it is destined to become a major health problem, including in many Asia Pacific region countries. Most cases of lung cancer are classified as non-small cell lung cancer (NSCLC).