Please use this identifier to cite or link to this item: http://hdl.handle.net/1959.13/27570
- Trisphaerolide A, a novel polyketide from the Dominican sponge Erylus trisphaerus
van Altena , Ian;
van Soest , Rob;
Andersen, Raymond J.
- The structure of trisphaerolide A (1), a mildly cytotoxic metabolite isolated from extracts of the marine sponge Erylus trisphaerus collected in Dominica, has been elucidated by detailed analysis of spectroscopic data. Trisphaerolide A (1) has a putative polyketide biogenesis, incorporating a rare variant on the standard pathway, which involves the addition of methyl branches arising from C-2 carbons of acetate units to chain carbons that arise from C-1 of acetate units.
- Journal of Natural Products Vol. 66, Issue 4, p. 561-563
- Publisher Link
- American Chemical Society
- Resource Type
- journal article