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Zhang, Xu Dong

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Inhibition of MEK blocks GRP78 up-regulation and enhances apoptosis induced by ER stress in gastric cancer cells 122 114 0
OBATOCLAX and ABT-737 induce ER stress responses in human melanoma cells that limit induction of apoptosis 84 82 0
Autophagy facilitates TLR4- and TLR3-triggered migration and invasion of lung cancer cells through the promotion of TRAF6 ubiquitination 23 19 0
Human melanoma cells selected for resistance to apoptosis by prolonged exposure to tumor necrosis factor-related apoptosis-inducing ligand are more vulnerable to necrotic cell death induced by cisplatin 55 51 0
Evidence for upregulation of Bim and the splicing factor SRp55 in melanoma cells from patients treated with selective BRAF inhibitors 56 52 3
TRIM16 inhibits proliferation and migration through regulation of interferon beta 1 in melanoma cells 52 40 0
Involvement of endoplasmic reticulum stress in docetaxel-induced JNK-dependent apoptosis of human melanoma 147 143 0
Melanoma cell sensitivity to docetaxal-induced apoptosis is determined by class III β-tubulin levels 98 89 0
Guidelines for the use and interpretation of assays for monitoring autophagy 17 7 0
Up-regulation of Mcl-1 is critical for survival of human melanoma cells upon endoplasmic reticulum stress 147 134 0
Applications of nanotechnology for melanoma treatment, diagnosis, and theranostics 52 50 1
Lactate dehydrogenase 5 expression in melanoma increases with disease progression and is associated with expression of Bcl-XL and Mcl-1, but not Bcl-2 proteins 97 96 0
Progression in melanoma is associated with decreased expression of death receptors for tumor necrosis factor–related apoptosis-inducing ligand 108 97 0
MEK-independent survival of B-RAFV600E melanoma cells selected for resistance to apoptosis induced by the RAF inhibitor PLX4720 62 54 1
Treatment combinations targeting apoptosis to improve immunotherapy of melanoma 84 79 2
PI(4,5)P2 5-phosphatase A regulates PI3K/Akt signalling and has a tumour suppressive role in human melanoma 255 244 1
Obesity and melanoma: exploring molecular links 17 14 0
Adaptation to ER stress as a driver of malignancy and resistance to therapy in human melanoma 86 78 3
Noxa upregulation by oncogenic activation of MEK/ERK through CREB promotes autophagy in human melanoma cells 22 21 0
Inhibition of endoplasmic reticulum stress-induced apoptosis of melanoma cells by the ARC protein 79 77 0
Human melanoma cells under endoplasmic reticulum stress acquire resistance to microtubule-targeting drugs through XBP-1-mediated activation of Akt 136 130 0
Sustained IRE1 and ATF6 signaling is important for survival of melanoma cells undergoing ER stress 10 8 0
The BH3-mimetic ABT-737 sensitizes human melanoma cells to apoptosis induced by selective BRAF inhibitors but does not reverse acquired resistance 15 13 0
Antiproliferative effects of continued mitogen-activated protein kinase pathway inhibition following acquired resistance to BRAF and/or MEK inhibition in melanoma 94 87 1
Contrasting effects of Nutlin-3 on TRAIL- and Docetaxel-induced Apoptosis due to upregulation of TRAIL-R2 and Mcl-1 in human melanoma cells 159 155 0
MicroRNA-149*, a p53-responsive microRNA, functions as an oncogenic regulator in human melanoma 104 98 1
Dissecting the signaling pathways that mediate cancer in PTEN and LKB1 double-knockout mice 0 0 0
Expression of glucose-regulated stress protein GRP78 is related to progression of melanoma 104 93 0
INPP4B is upregulated and functions as an oncogenic driver through SGK3 in a subset of melanomas 1 1 0
Insulin induces drug resistance in melanoma through activation of the PI3K/Akt pathway 39 37 0
Human melanoma cells under endoplasmic reticulum stress are more susceptible to apoptosis induced by the BH3 mimetic obatoclax 147 142 0
Palmitoylation of CD36/FAT regulates the rate of its post-transcriptional processing in the endoplasmic reticulum 134 122 0
Overcoming resistance to apoptosis in cancer therapy 98 86 0
Small molecular weight variants of p53 are expressed in human melanoma cells and are induced by the DNA-damaging agent cisplatin 149 141 0
Modulation of NOXA and MCL-1 as a strategy for sensitizing melanoma cells to the BH3-mimetic ABT-737 6 6 0
TRAIL-induced apoptosis of human melanoma cells involves activation of caspase-4 58 54 0
Nucleotide excision repair gene expression after cisplatin treatment in melanoma 150 136 0
The application of fungal beta-glucans for the treatment of colon cancer 20 17 0
Dual processing of FAT1 cadherin protein by human melanoma cells generates distinct protein products 328 296 18
Inhibition of apoptosis facilitates necrosis induced by cisplatin in gastric cancer cells 155 147 0
Translational control of tumor necrosis factor-related apoptosis-inducing ligand death receptor expression in melanoma cells 78 77 0
Regulators of global genome repair do not respond to DNA damaging therapy but correlate with survival in melanoma 103 98 3
2-Deoxy-D-glucose enhances TRAIL-induced apoptosis in human melanoma cells through XBP-1-mediated up-regulation of TRAIL-R2 217 203 6
Macrophage migration inhibitory factor engages PI3K/Akt signalling and is a prognostic factor in metastatic melanoma 26 20 0
Suppression of endoplasmic reticulum stress-induced invasion and migration of breast cancer cells through the downregulation of heparanase 32 30 1
Low expression of microRNA-146b-5p and microRNA-320d predicts poor outcome of large B-cell lymphoma treated with cyclophosphamide, doxorubicin, vincristine, and prednisone 36 28 3
Loss of PI(4,5)P₂ 5-phosphatase A contributes to resistance of human melanoma cells to RAF/MEK inhibitors 67 64 1
Glucose-regulated protein 78 antagonizes cisplatin and adriamycin in human melanoma cells 125 116 0
The emerging important role of microRNAs in the pathogenesis, diagnosis and treatment of human cancers 32 30 0
Metabolic approaches to treatment of melanoma 128 119 4
Activation of Jun N-terminal kinase is a mediator of vincristine-induced apoptosis of melanoma cells 237 226 0
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